Search Results - "Binder, Raquel A."

TMEM41B is a host factor required for the replication of diverse coronaviruses including SARS-CoV-2 by Trimarco, Joseph D, Heaton, Brook E, Chaparian, Ryan R, Burke, Kaitlyn N, Binder, Raquel A, Gray, Gregory C, Smith, Clare M, Menachery, Vineet D, Heaton, Nicholas S

“…Antiviral therapeutics are a front-line defense against virally induced diseases. Because viruses frequently mutate to escape direct inhibition of viral…”
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Minding the margins: Evaluating the impact of COVID-19 among Latinx and Black communities with optimal qualitative serological assessment tools by Binder, Raquel A, Matta, Angela M, Forconi, Catherine S, Oduor, Cliff I, Bedekar, Prajakta, Patrone, Paul N, Kearsley, Anthony J, Odwar, Boaz, Batista, Jennifer, Forrester, Sarah N, Leftwich, Heidi K, Cavacini, Lisa A, Moormann, Ann M

“…COVID-19 disproportionately affected minorities, while research barriers to engage underserved communities persist. Serological studies reveal infection and…”
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Clinical Utility of SARS-CoV-2 Serological Testing and Defining a Correlate of Protection by Sobhani, Kimia, Cheng, Susan, Binder, Raquel A, Mantis, Nicholas J, Crawford, James M, Okoye, Nkemakonam, Braun, Jonathan G, Joung, Sandy, Wang, Minhao, Lozanski, Gerard, King, Christopher L, Roback, John D, Granger, Douglas A, Boppana, Suresh B, Karger, Amy B

“…Herein, we review established clinical use cases for SARS-CoV-2 antibody measures, which include diagnosis of recent prior infection, isolating high titer…”
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A pan-coronavirus RT-PCR assay for rapid viral screening of animal, human, and environmental specimens by Wang, Xinye, Xiu, Leshan, Binder, Raquel A., Toh, Teck-Hock, Lee, Jeffrey Soon-Yit, Ting, Jakie, Than, Son T., Qi, Wenhao, Coleman, Kristen K., Perera, David, Ma, Maijuan, Gray, Gregory C.

“…We examined a collection of 386 animal, 451 human, and 109 archived bioaerosol samples with a new pan-species coronavirus molecular assay. Thirty-eight (4.02%)…”
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Viral genome-based Zika virus transmission dynamics in a paediatric cohort during the 2016 Nicaragua epidemic by Sun, Haoyang, Binder, Raquel A., Dickens, Borame, de Sessions, Paola Florez, Rabaa, Maia A., Ho, Eliza Xin Pei, Cook, Alex R, Carrillo, Fausto Bustos, Monterrey, Jairo Carey, Kuan, Guillermina, Balmaseda, Angel, Ooi, Eng Eong, Harris, Eva, Sessions, October M.

“…Nicaragua experienced a large Zika epidemic in 2016, with up to 50% of the population in Managua infected. With the domesticated Aedes aegypti mosquito as its…”
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Leptospirosis infections among hospital patients, Sarawak, Malaysia by Hii, King-Ching, Robie, Emily R., Saihidi, Izreena, Berita, Antoinette, Alarja, Natalie A., Xiu, Leshan, Merchant, James A., Binder, Raquel A., Goh, Johnny Keh-Tun, Guernier-Cambert, Vanina, Galán, Diego, Gregory, Michael J., Gray, Gregory C.

“…Abstract Background Leptospirosis diagnoses have increased in Sarawak, Malaysia in recent years. Methods To better understand the burden of disease and…”
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Environmental and Aerosolized Severe Acute Respiratory Syndrome Coronavirus 2 Among Hospitalized Coronavirus Disease 2019 Patients by Binder, Raquel A, Alarja, Natalie A, Robie, Emily R, Kochek, Kara E, Xiu, Leshan, Rocha-Melogno, Lucas, Abdelgadir, Anfal, Goli, Sumana V, Farrell, Amanda S, Coleman, Kristen K, Turner, Abigail L, Lautredou, Cassandra C, Lednicky, John A, Lee, Mark J, Polage, Christopher R, Simmons, Ryan A, Deshusses, Marc A, Anderson, Benjamin D, Gray, Gregory C

“…Abstract During April and May 2020, we studied 20 patients hospitalized with coronavirus disease 2019 (COVID-19), their hospital rooms (fomites and aerosols),…”
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Dengue and Zika virus infections in children elicit cross-reactive protective and enhancing antibodies that persist long term by Katzelnick, Leah C, Zambrana, Jose Victor, Elizondo, Douglas, Collado, Damaris, Garcia, Nadezna, Arguello, Sonia, Mercado, Juan Carlos, Miranda, Tatiana, Ampie, Oscarlett, Mercado, Brenda Lopez, Narvaez, César, Gresh, Lionel, Binder, Raquel A, Ojeda, Sergio, Sanchez, Nery, Plazaola, Miguel, Latta, Krista, Schiller, Amy, Coloma, Josefina, Carrillo, Fausto Bustos, Narvaez, Federico, Halloran, M Elizabeth, Gordon, Aubree, Kuan, Guillermina, Balmaseda, Angel, Harris, Eva

“…Dengue virus serotypes 1 to 4 (DENV1–4) and Zika virus (ZIKV) are mosquito-borne flaviviruses that induce both virus-specific and broadly reactive antibodies…”
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A RT-PCR assay for the detection of coronaviruses from four genera by Xiu, Leshan, Binder, Raquel A., Alarja, Natalie A., Kochek, Kara, Coleman, Kristen K., Than, Son T., Bailey, Emily S., Bui, Vuong N., Toh, Teck-Hock, Erdman, Dean D., Gray, Gregory C.

“…•We developed a diagnostic to detect all CoVs from the four main genera.•This assay can detect and identify all previously recognized CoVs and any future…”
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Six Decades of Human Adenovirus Type 4 Infections Reviewed: Increasing Infections Among Civilians Are a Matter of Concern by Coleman, Kristen K, Robie, Emily R, Abdelgadir, Anfal, Kozhumam, Arthi S, Binder, Raquel A, Gray, Gregory C

“…Abstract Human adenovirus type 4 (HAdV-E4) frequently causes epidemics among military and civilian populations. We conducted a systematic review of 144…”
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Live SARS‐CoV‐2 is difficult to detect in patient aerosols by Robie, Emily R., Abdelgadir, Anfal, Binder, Raquel A., Gray, Gregory C.

“…Circumstantial evidence indicates that aerosol transmission is a likely contributor to the current pandemic, 1‐3 yet research teams have had difficulty…”
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SARS-CoV-2 Serosurveys: How Antigen, Isotype and Threshold Choices Affect the Outcome by Binder, Raquel A, Fujimori, Gavin F, Forconi, Catherine S, Reed, George W, Silva, Leandro S, Lakshmi, Priya Saikumar, Higgins, Amanda, Cincotta, Lindsey, Dutta, Protiva, Salive, Marie-Claire, Mangolds, Virginia, Anya, Otuwe, Calvo Calle, J Mauricio, Nixon, Thomas, Tang, Qiushi, Wessolossky, Mireya, Wang, Yang, Ritacco, Dominic A, Bly, Courtney S, Fischinger, Stephanie, Atyeo, Caroline, Oluoch, Peter O, Odwar, Boaz, Bailey, Jeffrey A, Maldonado-Contreras, Ana, Haran, John P, Schmidt, Aaron G, Cavacini, Lisa, Alter, Galit, Moormann, Ann M

“…Evaluating the performance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological assays and clearly articulating the utility of selected…”
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Development of flow cytometry‐based assays to assess the ability of antibodies to bind to SARS‐CoV‐2‐infected and spike‐transfected cells and mediate NK cell degranulation by Mielke, Dieter, Stanfield‐Oakley, Sherry, Jha, Shalini, Keyes, Taylor, Zalaquett, Adam, Dunn, Brooke, Rodgers, Nicole, Oguin, Thomas, Sempowski, Greg D., Binder, Raquel A., Gray, Gregory C., Karuna, Shelly, Corey, Lawrence, Hural, John, Tomaras, Georgia D., Pollara, Justin, Ferrari, Guido

“…Since the beginning of the SARS‐CoV‐2 pandemic, antibody responses and antibody effector functions targeting SARS‐CoV‐2‐infected cells have been understudied…”
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Pseudo-outbreak of adenovirus in bronchoscopy suite by Seidelman, Jessica L, Akinboyo, Ibukunoluwa C, Taylor, Bonnie, Henshaw, Nancy G, Abdelgadir, Anfal, Gray, Gregory C, Smith, Becky A, Lewis, Sarah S

“…The clinical and infection control specimens were examined with eSensor Respiratory Viral Panel (RVP; GenMark Diagnostics, Carlsbad, CA) platform using the…”
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Environmental and Aerosolized SARS-CoV-2 Among Hospitalized COVID-19 Patients by Binder, Raquel A, Alarja, Natalie A, Robie, Emily R, Kochek, Kara E, Xiu, Leshan, Rocha-Melogno, Lucas, Abdelgadir, Anfal, Goli, Sumana V, Farrell, Amanda S, Coleman, Kristen K, Turner, Abigail L, Lautredou, Cassandra C, Lednicky, John A, Lee, Mark J, Polage, Christopher R, Simmons, Ryan A, Deshusses, Marc A, Anderson, Benjamin D, Gray, Gregory C

“…During April and May 2020, we studied 20 hospitalized COVID-19 patients, their hospital rooms (fomites and aerosols), and their close contacts for molecular…”
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The Serological Sciences Network (SeroNet) for COVID-19: Depth and Breadth of Serology Assays and Plans for Assay Harmonization by Karger, Amy B, Brien, James D, Christen, Jayne M, Dhakal, Santosh, Kemp, Troy J, Klein, Sabra L, Pinto, Ligia A, Premkumar, Lakshmanane, Roback, John D, Binder, Raquel A, Boehme, Karl W, Boppana, Suresh, Cordon-Cardo, Carlos, Crawford, James M, Daiss, John L, Dupuis, 2nd, Alan P, Espino, Ana M, Firpo-Betancourt, Adolfo, Forconi, Catherine, Forrest, J Craig, Girardin, Roxie C, Granger, Douglas A, Granger, Steve W, Haddad, Natalie S, Heaney, Christopher D, Hunt, Danielle T, Kennedy, Joshua L, King, Christopher L, Krammer, Florian, Kruczynski, Kate, LaBaer, Joshua, Lee, F Eun-Hyung, Lee, William T, Liu, Shan-Lu, Lozanski, Gerard, Lucas, Todd, Mendu, Damodara Rao, Moormann, Ann M, Murugan, Vel, Okoye, Nkemakonam C, Pantoja, Petraleigh, Payne, Anne F, Park, Jin, Pinninti, Swetha, Pinto, Amelia K, Pisanic, Nora, Qiu, Ji, Sariol, Carlos A, Simon, Viviana, Song, Lusheng, Steffen, Tara L, Stone, E Taylor, Styer, Linda M, Suthar, Mehul S, Thomas, Stefani N, Thyagarajan, Bharat, Wajnberg, Ania, Yates, Jennifer L, Sobhani, Kimia

“…In October 2020, the National Cancer Institute (NCI) Serological Sciences Network (SeroNet) was established to study the immune response to COVID-19, and "to…”
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Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies by Figueiredo, Jane C, Hirsch, Fred R, Kushi, Lawrence H, Nembhard, Wendy N, Crawford, James M, Mantis, Nicholas, Finster, Laurel, Merin, Noah M, Merchant, Akil, Reckamp, Karen L, Melmed, Gil Y, Braun, Jonathan, McGovern, Dermot, Parekh, Samir, Corley, Douglas A, Zohoori, Namvar, Amick, Benjamin C, Du, Ruofei, Gregersen, Peter K, Diamond, Betty, Taioli, Emanuela, Sariol, Carlos, Espino, Ana, Weiskopf, Daniela, Gifoni, Alba, Brien, James, Hanege, William, Lipsitch, Marc, Zidar, David A, Scheck McAlearney, Ann, Wajnberg, Ania, LaBaer, Joshua, Yvonne Lewis, E, Binder, Raquel A, Moormann, Ann M, Forconi, Catherine, Forrester, Sarah, Batista, Jennifer, Schieffelin, John, Kim, Dongjoo, Biancon, Giulia, VanOudenhove, Jennifer, Halene, Stephanie, Fan, Rong, Barouch, Dan H, Alter, Galit, Pinninti, Swetha, Boppana, Suresh B, Pati, Sunil K, Latting, Misty, Karaba, Andrew H, Roback, John, Sekaly, Rafick, Neish, Andrew, Brincks, Ahnalee M, Granger, Douglas A, Karger, Amy B, Thyagarajan, Bharat, Thomas, Stefani N, Klein, Sabra L, Cox, Andrea L, Lucas, Todd, Furr-Holden, Debra, Key, Kent, Jones, Nicole, Wrammerr, Jens, Suthar, Mehul, Yu Wong, Serre, Bowman, Natalie M, Simon, Viviana, Richardson, Lynne D, McBride, Russell, Krammer, Florian, Rana, Meenakshi, Kennedy, Joshua, Boehme, Karl, Forrest, Craig, Granger, Steve W, Heaney, Christopher D, Knight Lapinski, Maria, Wallet, Shannon, Baric, Ralph S, Schifanella, Luca, Lopez, Marcos, Fernández, Soledad, Kenah, Eben, Panchal, Ashish R, Britt, William J, Sanz, Iñaki, Dhodapkar, Madhav, Ahmed, Rafi, Bartelt, Luther A, Markmann, Alena J, Lin, Jessica T, Hagan, Robert S, Wolfgang, Matthew C, Skarbinski, Jacek

“…Abstract Background Global efforts are needed to elucidate the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the underlying…”
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Analysis of Diagnostics (Part II): Prevalence, Linear Independence, and Unsupervised Learning by Patrone, Paul N, Binder, Raquel A, Forconi, Catherine S, Moormann, Ann M, Kearsley, Anthony J

“…This is the second manuscript in a two-part series that uses diagnostic testing to understand the connection between prevalence (i.e. number of elements in a…”
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Analysis of Diagnostics (Part I): Prevalence, Uncertainty Quantification, and Machine Learning by Patrone, Paul N, Binder, Raquel A, Forconi, Catherine S, Moormann, Ann M, Kearsley, Anthony J

“…Diagnostic testing provides a unique setting for studying and developing tools in classification theory. In such contexts, the concept of prevalence, i.e. the…”
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