Search Results - "Binder, Matthew"

Semi-natural housing rescues social behavior and reduces repetitive exploratory behavior of BTBR autistic-like mice by Binder, Matthew S., Bordey, Angelique

“…Environmental enrichment confers numerous benefits when implemented in murine models and can reduce behavioral symptomatology in models of disease, such as…”
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The roles of molecular chaperones in regulating cell metabolism by Binder, Matthew J., Pedley, Anthony M.

“…Fluctuations in nutrient and biomass availability, often as a result of disease, impart metabolic challenges that must be overcome in order to sustain cell…”
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Reducing Filamin A Restores Cortical Synaptic Connectivity and Early Social Communication Following Cellular Mosaicism in Autism Spectrum Disorder Pathways by Binder, Matthew S, Escobar, Iris, Xu, Youfen, Sokolov, Aidan M, Zhang, Longbo, Bordey, Angélique

“…Communication in the form of nonverbal, social vocalization, or crying is evolutionary conserved in mammals and is impaired early in human infants that are…”
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The Novel Somatosensory Nose-Poke Adapted Paradigm (SNAP) Is an Effective Tool to Assess Differences in Tactile Sensory Preferences in Autistic-Like Mice by Binder, Matthew S., Bordey, Angelique

“…One of the most prevalent deficits in autism spectrum disorder (ASD) are sensitivities to sensory stimuli. Despite the prevalence of sensory deficits in…”
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Evaluating the DeepSqueak and Mouse Song Analyzer vocalization analysis systems in C57BL/6J, FVB.129, and FVB neonates by Binder, Matthew S., Pranske, Zachary J., Lugo, Joaquin N.

“…Communication is an essential behavior in mammals. Alterations in communication (neonatal crying) characterize numerous human neurodevelopmental conditions…”
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Dietary rescue of adult behavioral deficits in the Fmr1 knockout mouse by Nolan, Suzanne O, Hodges, Samantha L, Binder, Matthew S, Smith, Gregory D, Okoh, James T, Jefferson, Taylor S, Escobar, Brianna, Lugo, Joaquin N

“…The current study aimed to further address important questions regarding the therapeutic efficacy of omega-3 fatty acids for various behavioral and neuroimmune…”
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An Acute Seizure Prior to Memory Reactivation Transiently Impairs Associative Memory Performance in C57BL/6J Mice by Binder, Matthew S, Kim, Andrew D, Lugo, Joaquin N

“…Memory deficits significantly decrease an individual's quality of life and are a pervasive comorbidity of epilepsy. Despite the various distinct processes of…”
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NS‐Pten knockout mice show sex‐ and age‐specific differences in ultrasonic vocalizations by Binder, Matthew S., Lugo, Joaquin N.

“…Objective The goal of this study was to identify changes in quantitative and qualitative aspects of neonatal ultrasonic vocalizations USVs in neuron‐subset…”
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NS-Pten adult knockout mice display both quantitative and qualitative changes in urine-induced ultrasonic vocalizations by Binder, Matthew S., Jones, Dalton G., Hodges, Samantha L., Lugo, Joaquin N.

“…•NS-Pten KO mice display both quantitative and qualitative changes in USVs.•NS-Pten KO mice emit USVs of a lower peak frequency than WT mice.•NS-Pten KO’s emit…”
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CD-1 Outbred Mice Produce Less Variable Ultrasonic Vocalizations Than FVB Inbred Mice, While Displaying a Similar Developmental Trajectory by Binder, Matthew S., Shi, Hannah D., Bordey, Angelique

“…The production of ultrasonic vocalizations (USVs) in neonatal mice is a critical means of communication that is used to elicit maternal care. Alterations in…”
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Agomelatine Is Unable to Attenuate Kainic Acid–Induced Deficits in Early Life Communicative Behavior by Binder, Matthew S., Pranske, Zachary J., Hodges, Samantha L., Womble, Paige D., Kwok, Eliesse M., Quintero, Saul I., Kim, Andrew D., Narvaiz, David A., Lugo, Joaquin N.

“…ABSTRACT Early life seizures are associated with a variety of behavioral comorbidities. Among the most prevalent of these are deficits in communication…”
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Neonatal immune stimulation results in sex‐specific changes in ultrasonic vocalizations but does not affect seizure susceptibility in neonatal mice by Santana‐Coelho, Danielle, Pranske, Zachary J., Nolan, Suzanne O., Hodges, Samantha L., Binder, Matthew S., Womble, Paige D., Narvaiz, David A., Muhammad, Ilyasah, Lugo, Joaquin N.

“…Neuroinflammation during the neonatal period has been linked to disorders such as autism and epilepsy. In this study, we investigated the early life behavioral…”
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Prenatal High-Fat Diet Rescues Communication Deficits in Fmr1 Mutant Mice in a Sex-Specific Manner by Nolan, Suzanne O, Hodges, Samantha L, Okoh, James T, Binder, Matthew S, Lugo, Joaquin N

“…Using high-throughput analysis methods, the present study sought to determine the impact of prenatal high-fat dietary manipulations on isolation-induced…”
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Rapamycin, but not minocycline, significantly alters ultrasonic vocalization behavior in C57BL/6J pups in a flurothyl seizure model by Hodges, Samantha L., Womble, Paige D., Kwok, Eliesse M., Darner, Alyssa M., Senger, Savannah S., Binder, Matthew S., Faust, Amanda M., Condon, Siena M., Nolan, Suzanne O., Quintero, Saul I., Lugo, Joaquin N.

“…[Display omitted] •Early-life seizures increased ultrasonic vocalization (USV) quantity in female mice.•Rapamycin reduced USV emission and duration in both…”
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Vitamin D supplementation positively affects activity but impairs stimulus response behavior in an age and sex specific manner in C57BL/6 mice by Narvaiz, David A., Kwok, Eliesse M., Hodges, Samantha L., Binder, Matthew S., Nolan, Suzanne O., Pranske, Zachary J., Senger, Savannah, Herrera, Rebecca, Lugo, Joaquin N.

“…Several studies have begun to demonstrate the possible cognitive and physiological benefits of a fortified vitamin D diet. However, the behavioral effects of a…”
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A single early-life seizure results in long-term behavioral changes in the adult Fmr1 knockout mouse by Hodges, Samantha L., Reynolds, Conner D., Nolan, Suzanne O., Huebschman, Jessica L., Okoh, James T., Binder, Matthew S., Lugo, Joaquin N.

“…•Early-life seizures increased repetitive behavior in adult wild type (WT) mice.•Repetitive behavior in Fmr1 knockout mice was not exacerbated following…”
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Lipopolysaccharide-induced inflammation leads to acute elevations in pro-inflammatory cytokine expression in a mouse model of Fragile X syndrome by Hodges, Samantha L., Nolan, Suzanne O., Tomac, Lindsay A., Muhammad, Ilyasah D.A., Binder, Matthew S., Taube, Joseph H., Lugo, Joaquin N.

“…•Acute elevations in IL-1β and IL-6 expression in Fmr1 knock out (KO) mice.•No differences detected in cytokine expression 24 h post-immune stimulation.•Fmr1…”
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A vitamin D enriched diet attenuates sex-specific behavioral deficits, increases the lifespan, but does not rescue bone abnormalities in a mouse model of cortical dysplasia by Womble, Paige D., Hodges, Samantha L., Nolan, Suzanne O., Binder, Matthew S., Holley, Andrew J., Herrera, Rebecca, Senger, Savannah, Kwok, Eliesse, Narviaz, David A., Faust, Amanda, Hernandez-Zegada, Christian J., Kwon, Ronald Y., Lugo, Joaquin N.

“…[Display omitted] •Vitamin D enriched diet attenuated hypoactivity and rearing in the open-field test.•Vitamin D enriched diet increased percent survival in…”
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A flurothyl-induced seizure does not disrupt hippocampal memory reconsolidation in C57BL/6 J mice by Binder, Matthew S., Prankse, Zachary J., Kim, Andrew D., Hodges, Samantha L., Narvaiz, David A., Womble, Paige D., Lugo, Joaquin N.

“…Memory deficits are a prevalent and pervasive comorbidity of epilepsy that significantly decrease an individual’s quality of life. Numerous studies have…”
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A comparison of the Avisoft (5.2) and Ultravox (2.0) recording systems: Implications for early-life communication and vocalization research by Binder, Matthew S., Hernandez-Zegada, Christian J., Potter, Christian T., Nolan, Suzanne O., Lugo, Joaquin N.

“…[Display omitted] •Avisoft detected more vocalizations overall than Ultravox.•Avisoft detected more total vocalizations at 50, 60, and 70 kHz than…”
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