Search Results - "Binaschi, Anna"
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Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon Vectors
Published in PloS one (08-03-2016)“…Brain-derived neurotrophic factor (BDNF) has been found to produce pro- but also anti-epileptic effects. Thus, its validity as a therapeutic target must be…”
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2
Localized delivery of fibroblast growth factor-2 and brain-derived neurotrophic factor reduces spontaneous seizures in an epilepsy model
Published in Proceedings of the National Academy of Sciences - PNAS (28-04-2009)“…A loss of neurons is observed in the hippocampus of many patients with epilepsies of temporal lobe origin. It has been hypothesized that damage limitation or…”
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3
Bystander effect on brain tissue of mesoangioblasts producing neurotrophins
Published in Cell transplantation (01-01-2012)“…Neurotrophic factors (NTFs) are involved in the regulation of neuronal survival and function and, thus, may be used to treat neurological diseases associated…”
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4
On the role of somatostatin in seizure control: clues from the hippocampus
Published in Reviews in the neurosciences (2003)“…The role of the hippocampal somatostatin (somatotropin release-inhibiting factor, SRIF) system in the control of partial complex seizures is discussed in this…”
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MicroRNA profiles in hippocampal granule cells and plasma of rats with pilocarpine-induced epilepsy – comparison with human epileptic samples
Published in Scientific reports (18-09-2015)“…The identification of biomarkers of the transformation of normal to epileptic tissue would help to stratify patients at risk of epilepsy following brain injury…”
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Impairment of GABA release in the hippocampus at the time of the first spontaneous seizure in the pilocarpine model of temporal lobe epilepsy
Published in Experimental neurology (01-07-2014)“…The alterations in GABA release have not yet been systematically measured along the natural course of temporal lobe epilepsy. In this work, we analyzed GABA…”
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Personalized Needles for Microinjections in the Rodent Brain
Published in Journal of visualized experiments (24-01-2018)“…Microinjections have been used for a long time for the delivery of drugs or toxins within specific brain areas and, more recently, they have been used to…”
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Personalized Needles for Microinjections in the Rodent Brain
Published in Journal of visualized experiments (24-01-2018)Get full text
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9
FGF-2 Overexpression Increases Excitability and Seizure Susceptibility but Decreases Seizure-Induced Cell Loss
Published in The Journal of neuroscience (03-12-2008)“…Fibroblast growth factor 2 (FGF-2) has multiple, pleiotropic effects on the nervous system that include neurogenesis, neuroprotection and neuroplasticity…”
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10
Silencing Status Epilepticus-Induced BDNF Expression with Herpes Simplex Virus Type-1 Based Amplicon Vectors: e0150995
Published in PloS one (01-03-2016)“…Brain-derived neurotrophic factor (BDNF) has been found to produce pro- but also anti-epileptic effects. Thus, its validity as a therapeutic target must be…”
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11
Kainate seizures increase nociceptin/orphanin FQ release in the rat hippocampus and thalamus: a microdialysis study
Published in Journal of neurochemistry (01-10-2004)“…The neuropeptide nociceptin/orphanin FQ (N/OFQ) has been suggested to play a facilitatory role in kainate seizure expression. Furthermore, mRNA levels for the…”
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Involvement of the Neuropeptide Nociceptin/Orphanin FQ in Kainate Seizures
Published in The Journal of neuroscience (15-11-2002)“…The neuropeptide nociceptin/orphanin FQ (N/OFQ) has been shown to modulate neuronal excitability and neurotransmitter release. Previous studies indicate that…”
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13
Delayed epileptogenesis in nociceptin/orphanin FQ-deficient mice
Published in Neuroreport (06-05-2003)“…The neuropeptide nociceptin/orphanin FQ (N/OFQ) is implicated in many biological functions, including nociception, locomotor activity, stress and anxiety,…”
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14
Kindled seizure-evoked somatostatin release in the hippocampus: inhibition by MK-801
Published in Neuroreport (28-09-2000)“…The aim of this study was to evaluate the contribution of ionotropic glutamate receptors to kindled seizure-evoked somatostatin release in the hippocampus,…”
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