Search Results - "Bimpisidis, Zisis"

Increased sucrose consumption in mice gene-targeted for Vmat2 selectively in NeuroD6-positive neurons of the ventral tegmental area by Bimpisidis, Zisis, Serra, Gian Pietro, König, Niclas, Wallén-Mackenzie, Åsa

“…Ventral tegmental area (VTA) dopamine (DA) neurons are implicated in reward processing, motivation, reward prediction error, and in substance use disorder…”
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Selective Knockout of the Vesicular Monoamine Transporter 2 (Vmat2) Gene in Calbindin2/Calretinin-Positive Neurons Results in Profound Changes in Behavior and Response to Drugs of Abuse by König, Niclas, Bimpisidis, Zisis, Dumas, Sylvie, Wallén-Mackenzie, Åsa

“…The vesicular monoamine transporter 2 (VMAT2) has a range of functions in the central nervous system, from sequestering toxins to providing conditions for…”
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Levodopa-induced abnormal involuntary movements correlate with altered permeability of the blood-brain-barrier in the basal ganglia by Lerner, Renata P., Francardo, Veronica, Fujita, Koji, Bimpisidis, Zisis, Jourdain, Vincent A., Tang, Chris C., Dewey, Stephen L., Chaly, Thomas, Cenci, M. Angela, Eidelberg, David

“…Chronic levodopa treatment leads to the appearance of dyskinesia in the majority of Parkinson’s disease patients. Neurovascular dysregulation in putaminal and…”
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Modulating mGluR5 and 5-HT1A/1B receptors to treat l-DOPA-induced dyskinesia: Effects of combined treatment and possible mechanisms of action by Iderberg, Hanna, Rylander, Daniella, Bimpisidis, Zisis, Cenci, M. Angela

“…l-DOPA-induced dyskinesia (LID) is a major complication of the pharmacotherapy of Parkinson's disease. Emerging approaches to the treatment of LID include…”
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Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio by Papathanou, Maria, Creed, Meaghan, Dorst, Matthijs C, Bimpisidis, Zisis, Dumas, Sylvie, Pettersson, Hanna, Bellone, Camilla, Silberberg, Gilad, Lüscher, Christian, Wallén-Mackenzie, Åsa

“…Expression of the gene encoding the Vesicular glutamate transporter 2 (VGLUT2) in midbrain dopamine (DA) neurons enables these neurons to co-release glutamate…”
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Dissociation of metabolic and hemodynamic levodopa responses in the 6-hydroxydopamine rat model by Lerner, Renata P., Bimpisidis, Zisis, Agorastos, Stergiani, Scherrer, Sandra, Dewey, Stephen L., Cenci, M. Angela, Eidelberg, David

“…Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and in…”
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Immunology and microbiology: how do they affect social cognition and emotion recognition? by Barcik, Weronika, Chiacchierini, Giulia, Bimpisidis, Zisis, Papaleo, Francesco

“…•Microglia and astrocytes can modulate social behavior in mice and humans in a neurodevelopmental-dependent way.•Peripheral immune system can influence social…”
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Mechanisms of dopamine D1 receptor-mediated ERK1/2 activation in the parkinsonian striatum and their modulation by metabotropic glutamate receptor type 5 by Fieblinger, Tim, Sebastianutto, Irene, Alcacer, Cristina, Bimpisidis, Zisis, Maslava, Natallia, Sandberg, Sabina, Engblom, David, Cenci, M Angela

“…In animal models of Parkinson's disease, striatal overactivation of ERK1/2 via dopamine (DA) D1 receptors is the hallmark of a supersensitive molecular…”
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Neurocircuitry of Reward and Addiction: Potential Impact of Dopamine-Glutamate Co-release as Future Target in Substance Use Disorder by Bimpisidis, Zisis, Wallén-Mackenzie, Åsa

“…Dopamine-glutamate co-release is a unique property of midbrain neurons primarily located in the ventral tegmental area (VTA). Dopamine neurons of the VTA are…”
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Lactoferrin- and antitransferrin-modified liposomes for brain targeting of the NK3 receptor agonist senktide: Preparation and in vivo evaluation by De Luca, Maria Antonietta, Lai, Francesco, Corrias, Francesco, Caboni, Pierluigi, Bimpisidis, Zisis, Maccioni, Elias, Fadda, Anna Maria, Di Chiara, Gaetano

“…[Display omitted] The aim of this work was to evaluate the capability of lactoferrin- and antitransferrin-modified long circulating liposomes to deliver the…”
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Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid by De Luca, M.A., Bimpisidis, Z., Melis, M., Marti, M., Caboni, P., Valentini, V., Margiani, G., Pintori, N., Polis, I., Marsicano, G., Parsons, L.H., Di Chiara, G.

“…The synthetic cannabinoid 1-pentyl-3-(1-naphthoyl)-indole (JWH-018) has been detected in about 140 samples of a smokable herbal mixture termed “Spice”. JWH-018…”
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Midbrain Gene Screening Identifies a New Mesoaccumbal Glutamatergic Pathway and a Marker for Dopamine Cells Neuroprotected in Parkinson’s Disease by Viereckel, Thomas, Dumas, Sylvie, Smith-Anttila, Casey J. A., Vlcek, Bianca, Bimpisidis, Zisis, Lagerström, Malin C., Konradsson-Geuken, Åsa, Wallén-Mackenzie, Åsa

“…The ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) of the midbrain are associated with Parkinson’s disease (PD), schizophrenia, mood…”
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Lesion of medial prefrontal dopamine terminals abolishes habituation of accumbens shell dopamine responsiveness to taste stimuli by Bimpisidis, Zisis, De Luca, Maria Antonietta, Pisanu, Augusta, Di Chiara, Gaetano

“…Taste stimuli increase extracellular dopamine (DA) in the nucleus accumbens (NAc) and in the medial prefrontal cortex (mPFC). This effect shows single‐trial…”
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Differential effects of gaseous versus injectable anesthetics on changes in regional cerebral blood flow and metabolism induced by l-DOPA in a rat model of Parkinson's disease by Bimpisidis, Zisis, Öberg, Carl M., Maslava, Natallia, Cenci, M. Angela, Lundblad, Cornelia

“…Preclinical imaging of brain activity requires the use of anesthesia. In this study, we have compared the effects of two widely used anesthetics, inhaled…”
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Cannabinoid facilitation of behavioral and biochemical hedonic taste responses by De Luca, M.A., Solinas, M., Bimpisidis, Z., Goldberg, S.R., Di Chiara, G.

“…Cannabinoid receptor agonists are known to stimulate feeding in humans and animals and this effect is thought to be related to an increase in food…”
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6-Hydroxydopamine rat model by Lerner, Renata P, Bimpisidis, Zisis, Agorastos, Stergiani, Scherrer, Sandra, Dewey, Stephen L, Cenci, M. Angela, Eidelberg, David

“…Abstract Dissociation of vasomotor and metabolic responses to levodopa has been observed in human subjects with Parkinson's disease (PD) studied with PET and…”
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The NeuroD6 Subtype of VTA Neurons Contributes to Psychostimulant Sensitization and Behavioral Reinforcement by Bimpisidis, Zisis, König, Niclas, Stagkourakis, Stefanos, Zell, Vivien, Vlcek, Bianca, Dumas, Sylvie, Giros, Bruno, Broberger, Christian, Hnasko, Thomas S, Wallén-Mackenzie, Åsa

“…Reward-related behavior is complex and its dysfunction correlated with neuropsychiatric illness. Dopamine (DA) neurons of the ventral tegmental area (VTA) have…”
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Endocannabinoid 2-Arachidonoylglycerol Self-Administration by Sprague-Dawley Rats and Stimulation of in vivo Dopamine Transmission in the Nucleus Accumbens Shell by De Luca, Maria Antonietta, Valentini, Valentina, Bimpisidis, Zisis, Cacciapaglia, Fabio, Caboni, Pierluigi, Di Chiara, Gaetano

“…2-Arachidonoylglycerol (2-AG) is the most potent endogenous ligand of brain cannabinoid CB1 receptors and is synthesized on demand from…”
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Mechanisms of Dopamine D1 Receptor-Mediated ERK1/2 Activation in the Parkinsonian Striatum and Their Modulation by Metabotropic Glutamate Receptor Type 5 by Fieblinger, Tim, Sebastianutto, Irene, Alcacer, Cristina, Bimpisidis, Zisis, Maslava, Natallia, Sandberg, Sabina, Engblom, David, Cenci, Maria Angela

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Influence of morphine sensitization on the responsiveness of mesolimbic and mesocortical dopamine transmission to appetitive and aversive gustatory stimuli by De Luca, Maria Antonietta, Bimpisidis, Zisis, Bassareo, Valentina, Di Chiara, Gaetano

“…Rationale Repeated treatment with morphine has been shown to sensitize rats to its stimulant effects on motor activity and mesolimbic dopamine (DA)…”
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