Search Results - "Bilton, Rebecca"
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Prevalence and Preventability of Adverse Medicine Events in a Sample of Australian Aged-Care Residents: A Secondary Analysis of Data from the ReMInDAR Trial
Published in Drug safety (01-05-2023)“…Background Aged care residents are vulnerable to the harmful effects of medicines; however, data on the prevalence and preventability of adverse medicine…”
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Risk factors predictive of adverse drug events and drug-related falls in aged care residents: secondary analysis from the ReMInDAR trial
Published in Drugs & aging (01-01-2023)“…Background Residents of aged-care facilities have high rates of adverse drug events. This study aimed to identify risk factors for adverse drug events in…”
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Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways
Published in Proceedings of the National Academy of Sciences - PNAS (04-03-2008)“…Cells adapt to hypoxia by a cellular response, where hypoxia-inducible factor 1α (HIF-1α) becomes stabilized and directly activates transcription of downstream…”
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The quality of care delivered to residents in long-term care in Australia: an indicator-based review of resident records (CareTrack Aged study)
Published in BMC medicine (23-01-2024)“…This study estimated the prevalence of evidence-based care received by a population-based sample of Australian residents in long-term care (LTC) aged ≥…”
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Medicine-related problems: A recurrent issue among residents living in nursing homes
Published in Frontiers in pharmacology (29-08-2022)“…To examine the incidence and nature of medicine-related problems over time experienced by nursing home residents. We analyzed records collected in the Reducing…”
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Pharmacists as patient advocates: A series of case studies illustrating the impacts of a regular pharmacist service in residential aged care (nursing homes)
Published in Exploratory research in clinical and social pharmacy (01-06-2023)“…Medicine-related problems are common in older people living in residential aged care facilities (RACFs). Recognising the significant medicine-related problems,…”
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Frailty trajectory over one year among residential aged care (nursing home) residents
Published in Frontiers in medicine (03-11-2022)“…Objectives Large population-based studies examining frailty trajectory found a linear increase in frailty over time. The pattern in which frailty changes over…”
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HIF-1: master and commander of the hypoxic world: A pharmacological approach to its regulation by siRNAs
Published in Biochemical pharmacology (15-09-2004)“…The hypoxia-inducible factor-1 (HIF-1) is primarily involved in the sensing and adapting of cells to changes in the O 2 level, which is essential for their…”
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The subtle side to hypoxia inducible factor (HIFα) regulation
Published in European journal of biochemistry (01-03-2003)“…The transcription factor hypoxia inducible factor α‐subunit (HIFα) is pivotal in the cellular response to the stress of hypoxia. Post‐translational…”
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Exploring what matters to residents of Australian aged care facilities with the Happy Life Index: comparison of qualitative responses between pre- and mid-Covid-19 pandemic time points
Published in Quality of life research (01-08-2023)“…Purpose This study analysed data from a national survey of people living in Australian Residential Aged Care Facilities (RACFs) reporting on what is the best…”
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The Batten Disease Gene Product (CLN3p) Is a Golgi Integral Membrane Protein
Published in Human molecular genetics (01-03-1999)“…Batten disease (juvenile neuronal ceroid lipofuscinosis) is a recessive neurodegenerative disorder of childhood. The gene, CLN3, was recently identified and…”
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Using wrist-worn accelerometers to identify the impact of medicines with anticholinergic or sedative properties on sedentary time: A 12-month prospective analysis
Published in Maturitas (01-06-2023)“…•The effects of medicines on physical function have not been quantified.•We studied the association between medicine changes and 24-hour activity…”
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Direct health and residential care costs of people living with dementia in Australian residential aged care
Published in International journal of geriatric psychiatry (01-07-2018)“…Objectives This analysis estimates the whole‐of‐system direct costs for people living with dementia in residential care by using a broad health and social care…”
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Effect of an ongoing pharmacist service to reduce medicine-induced deterioration and adverse reactions in aged-care facilities (nursing homes): a multicentre, randomised controlled trial (the ReMInDAR trial)
Published in Age and ageing (01-04-2022)“…Abstract Objective To assess the effectiveness of a pharmacist-led intervention using validated tools to reduce medicine-induced deterioration and adverse…”
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Reducing medicine-induced deterioration and adverse reactions (ReMInDAR) trial: study protocol for a randomised controlled trial in residential aged-care facilities assessing frailty as the primary outcome
Published in BMJ open (22-04-2020)“…IntroductionMany medicines have adverse effects which are difficult to detect and frequently go unrecognised. Pharmacist monitoring of changes in signs and…”
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HIF-1: master and commander of the hypoxic world
Published in Biochemical pharmacology (01-09-2004)Get full text
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Activation of HIF-1α in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway
Published in Journal of cellular physiology (01-01-2009)“…Accumulation of HIF‐1α during normoxic conditions at high cell density has previously been shown to occur and can be used to stabilize HIF‐1α protein in the…”
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Arrest-defective-1 Protein, an Acetyltransferase, Does Not Alter Stability of Hypoxia-inducible Factor (HIF)-1α and Is Not Induced by Hypoxia or HIF
Published in The Journal of biological chemistry (02-09-2005)“…The hypoxia-inducible factor (HIF) is a key player in a transcriptional pathway that controls the hypoxic response of mammalian cells. Post-translational…”
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