Search Results - "Bilodeau, François"
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Correction to “NHC-Catalyzed Intramolecular Redox Amidation for the Synthesis of Functionalized Lactams”
Published in Organic letters (21-06-2024)Get full text
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Increased Dairy Product Intake Alters Serum Metabolite Profiles in Subjects at Risk of Developing Type 2 Diabetes
Published in Molecular nutrition & food research (01-10-2019)“…Scope Metabolomics is increasingly used to identify biomarkers of diet or chronic diseases, such as type 2 diabetes. Yet, metabolite signatures following dairy…”
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3
Dimensional reduction of a 3D thermoelectric model to create a reliable and time-efficient 2D model representing an aluminum electrolysis cell
Published in International journal of heat and mass transfer (01-03-2023)“…•New detailed protocol for creating a 2D model from a 3D thermoelectric model.•Protocol for model reduction adapted to 4.0 industrial revolution.•Digital twin…”
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NHC-Catalyzed Intramolecular Redox Amidation for the Synthesis of Functionalized Lactams
Published in Organic letters (17-12-2010)“…A very efficient NHC-catalyzed lactamization reaction is reported. For most cases, the ring expansion reaction proceeds to cleanly furnish five- and…”
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Marginal Impact of Brown Seaweed Ascophyllum nodosum and Fucus vesiculosus Extract on Metabolic and Inflammatory Response in Overweight and Obese Prediabetic Subjects
Published in Marine drugs (26-02-2022)“…The objective of the present study was to test whether a brown seaweed extract rich in polyphenols combined with a low-calorie diet would induce additional…”
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6
Trans Fatty Acids Suppress TNF-α-Induced Inflammatory Gene Expression in Endothelial (HUVEC) and Hepatocellular Carcinoma (HepG2) Cells
Published in Lipids (01-04-2017)“…Trans fatty acids (TFA) intake has been linked to cardiovascular diseases and liver diseases; yet the effect of TFA on inflammation remains controversial…”
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Mercury Export From Freshwater to Estuary: Carbocentric Science Elucidates the Fate of a Toxic Compound in Aquatic Boreal Environments
Published in Frontiers in environmental science (23-06-2021)“…The chemistry of mercury in freshwater systems, particularly man-made reservoirs, has received a great deal of attention owing to the high toxicity of the most…”
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Industrial and Ruminant Trans-Fatty Acids-Enriched Diets Differentially Modulate the Microbiome and Fecal Metabolites in C57BL/6 Mice
Published in Nutrients (01-03-2023)“…Industrially originated trans-fatty acids (I- FAs), such as elaidic acid (EA), and ruminant trans-fatty acids (R- FAs), such as -palmitoleic acid (TPA), may…”
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9
Fragment-Based Phenotypic Lead Discovery To Identify New Drug Seeds That Target Infectious Diseases
Published in ACS chemical biology (19-11-2021)“…Fragment-based lead discovery has emerged over the last decades as one of the most powerful techniques for identifying starting chemical matter to target…”
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Analysis of F2-isoprostanes in plasma of pregnant women by HPLC-MS/MS using a column packed with core-shell particles
Published in Journal of lipid research (01-05-2013)“…Plasma F2-isoprostanes (F2-isoPs) are reliable biomarkers of oxidative stress. Several possible F2-isoPs are generated by the oxidation of arachidonic acid…”
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Long chain omega-3 fatty acids and their oxidized metabolites are associated with reduced prostate tumor growth
Published in Prostaglandins, leukotrienes and essential fatty acids (01-01-2021)“…•The enriched ω−3 diet did not reduce oxidative stress overall in tumors but favored ω−3 rather than ω−6 LC-PUFA derived isoprostanes.•Neuroprostanes are…”
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Docosahexaenoic acid-rich algae oil supplementation in mothers of preterm infants is associated with a modification in breast milk oxylipins profile
Published in Lipids in health and disease (14-07-2023)“…Oxylipins are derived from enzymatic and non-enzymatic oxidation of n-3 and n-6 long-chain polyunsaturated fatty acids. They are known to be involved in…”
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High dairy products intake modifies the correlation between α-tocopherol levels and serum proteins related to lipid metabolism in subjects at risk of type 2 diabetes
Published in Journal of functional foods (01-01-2023)“…[Display omitted] •Increasing dietary fat intake could improve α-tocopherol bioavailability.•Proteomics offer a useful approach for identifying protein…”
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Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV‑1
Published in ACS medicinal chemistry letters (10-04-2014)“…An assay recapitulating the 3′ processing activity of HIV-1 integrase (IN) was used to screen the Boehringer Ingelheim compound collection. Hit-to-lead and…”
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Impact of cryopreservation and reactive oxygen species on DNA integrity, lipid peroxidation, and functional parameters in ram sperm
Published in Molecular reproduction and development (01-07-2007)“…Assisted reproduction using frozen‐thawed semen has practical advantages, although cryopreservation is detrimental to sperm fertility in most mammals. We…”
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Maternal vitamin D, oxidative stress, and pre‐eclampsia
Published in International journal of gynecology and obstetrics (01-09-2021)“…Objective To examine the associations between risk of pre‐eclampsia and pregnancy levels of maternal 25‐hydroxyvitamin D (25[OH]D) and oxidative stress…”
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Remodeling of lipid landscape in high fat fed very-long chain acyl-CoA dehydrogenase null mice favors pro-arrhythmic polyunsaturated fatty acids and their downstream metabolites
Published in Biochimica et biophysica acta. Molecular basis of disease (01-12-2023)“…Very-long chain acyl-CoA dehydrogenase (VLCAD) catalyzes the initial step of mitochondrial long chain (LC) fatty acid β-oxidation (FAO). Inherited VLCAD…”
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Alterations of fatty acid profiles in gestational diabetes and influence of the diet
Published in Maturitas (01-05-2017)“…Highlights • Higher saturated fatty acids (FA) and lower polyunsaturated FA levels in blood are characteristics of gestational diabetes mellitus (GDM). • FA…”
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Impact of Dairy Intake on Plasma F2-IsoProstane Profiles in Overweight Subjects with Hyperinsulinemia: A Randomized Crossover Trial
Published in Nutrients (18-06-2021)“…F2-IsoProstanes (F2-IsoPs) are major biomarkers of oxidative stress and are associated with type 2 diabetes (T2D). Further, plasma levels of F2-IsoPs may be…”
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Modulation of the biomarkers of inflammation and oxidative stress by ruminant trans fatty acids and dairy proteins in vascular endothelial cells (HUVEC)
Published in Prostaglandins, leukotrienes and essential fatty acids (01-11-2017)“…This study aimed to determine whether dairy macronutrients alter markers of inflammation and oxidative stress in endothelial cells. Human endothelial cells…”
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