Search Results - "Bilmen, Jonathan G"

Inhibition of the type 1 inositol 1,4,5-trisphosphate receptor by 2-aminoethoxydiphenylborate by Bilmen, Jonathan G, Michelangeli, Francesco

“…2-Aminoethoxydiphenylborate (2-APB) inhibits the extent of inositol 1,4,5-trisphosphate (InsP 3)-induced Ca 2+ release from cerebellar microsomes with a…”
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The novel rapid formulation of intravenous dantrolene (NPJ5008) versus standard dantrolene (Dantrium®): A clinical part-randomised phase 1 study in healthy volunteers by Ng Kwet Shing, Richard H, Clayton, Lucy B, Smith, Samuel L, Watson, Marc J, McKenzie, Litza M, Chalmers, David P, Whitaker, Gareth, Bilmen, Jonathan G

“…Delays in treating anaesthesia-induced malignant hyperthermia increase risks of complications and death. NPJ5008 is a novel formulation of the indicated…”
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The inhibition of the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase by macrocyclic lactones and cyclosporin A by Bilmen, Jonathan G, Wootton, Laura L, Michelangeli, Francesco

“…The pharmacology of macrocyclic lactones is varied, with many beneficial effects in treating disease processes. FK-506, rapamycin and ascomycin have been…”
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Malignant hyperthermia by Hopkins, Philip M, Gupta, Pawan K, Bilmen, Jonathan G

“…Malignant hyperthermia (MH) is a form of heat illness caused by increased heat generation exceeding the body's capacity for heat loss. It is classified…”
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The mechanism of inhibition of the sarco/endoplasmic reticulum Ca2+ ATPase by paxilline by Bilmen, Jonathan G, Wootton, Laura L, Michelangeli, Francesco

“…Paxilline, an indole alkaloid mycotoxin from Penicillium paxilli, is an inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA). Paxilline inhibited…”
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Inhibition of SERCA Ca2+ pumps by 2‐aminoethoxydiphenyl borate (2‐APB) by Bilmen, Jonathan G., Wootton, Laura L., Godfrey, Rita E., Smart, Oliver S., Michelangeli, Francesco

“…2‐Aminoethoxydiphenyl Borate (2‐APB) has been extensively used recently as a membrane permeable modulator of inositol‐1,4,5‐trisphosphate‐sensitive Ca2+…”
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Inhibition of the SERCA Ca2+ pumps by curcumin by Bilmen, Jonathan G., Khan, Shahla Zafar, Javed, Masood‐ul‐Hassan, Michelangeli, Francesco

“…Curcumin is a compound derived from the spice, tumeric. It is a potent inhibitor of the SERCA Ca2+ pumps (all isoforms), inhibiting Ca2+‐dependent ATPase…”
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Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB). 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites by Bilmen, Jonathan G, Wootton, Laura L, Godfrey, Rita E, Smart, Oliver S, Michelangeli, Francesco

“…2-Aminoethoxydiphenyl Borate (2-APB) has been extensively used recently as a membrane permeable modulator of inositol-1,4,5-trisphosphate-sensitive Ca2+…”
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The mechanism of inhibition of the sarco/endoplasmic reticulum Ca 2+ ATPase by paxilline by Bilmen, Jonathan G, Wootton, Laura L, Michelangeli, Francesco

“…Paxilline, an indole alkaloid mycotoxin from Penicillium paxilli, is an inhibitor of the sarco/endoplasmic reticulum Ca 2+ ATPase (SERCA). Paxilline inhibited…”
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Subtype identification and functional properties of inositol 1,4,5-trisphosphate receptors in heart and aorta by Tovey, Stephen C., Dyer, Jeanette L., Godfrey, Rita E., Khan, Shahla Zafar, Bilmen, Jonathan G., Mezna, Mokdad, Michelangeli, Francesco

“…One of the major mechanisms by which hormones elevate intracellular Ca2+levels is by generating the second messenger inositol 1,4,5-trisphosphate (InsP3),…”
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Inhibition of SERCA Ca 2+ pumps by 2‐aminoethoxydiphenyl borate (2‐APB): 2‐APB reduces both Ca 2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca 2+ ‐binding sites by Bilmen, Jonathan G., Wootton, Laura L., Godfrey, Rita E., Smart, Oliver S., Michelangeli, Francesco

“…2‐Aminoethoxydiphenyl Borate (2‐APB) has been extensively used recently as a membrane permeable modulator of inositol‐1,4,5‐trisphosphate‐sensitive Ca 2+…”
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Inhibition of the SERCA Ca 2+ pumps by curcumin: Curcumin putatively stabilizes the interaction between the nucleotide‐binding and phosphorylation domains in the absence of ATP by Bilmen, Jonathan G., Khan, Shahla Zafar, Javed, Masood‐ul‐Hassan, Michelangeli, Francesco

“…Curcumin is a compound derived from the spice, tumeric. It is a potent inhibitor of the SERCA Ca 2+ pumps (all isoforms), inhibiting Ca 2+ ‐dependent ATPase…”
Get full text