Search Results - "Billingham, Margaret"

Cardiovascular pathology at the crossroads: the dilemma of cardiac pathologists by Billingham, Margaret E

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Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection by Stewart, Susan, Winters, Gayle L, Fishbein, Michael C, Tazelaar, Henry D, Kobashigawa, Jon, Abrams, Jacki, Andersen, Claus B, Angelini, Annalisa, Berry, Gerald J, Burke, Margaret M, Demetris, Anthony J, Hammond, Elizabeth, Itescu, Silviu, Marboe, Charles C, McManus, Bruce, Reed, Elaine F, Reinsmoen, Nancy L, Rodriguez, E Rene, Rose, Alan G, Rose, Marlene, Suciu-Focia, Nicole, Zeevi, Adriana, Billingham, Margaret E

“…In 1990, an international grading system for cardiac allograft biopsies was adopted by the International Society for Heart Transplantation. This system has…”
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Rapamycin reverses chronic graft vascular disease in a novel cardiac allograft model by POSTON, R. S, BILLINGHAM, M, HOYT, E. G, POLLARD, J, SHORTHOUSE, R, MORRIS, R. E, ROBBINS, R. C

“…Chronic graft vascular disease (CGVD) in cardiac allografts has been defined as a slowly evolving vasculopathy unresponsive to conventional immunosuppression…”
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Pharmacodynamics of Mycophenolate Mofetil after Heart Transplantation: New Mechanisms of Action and Correlations with Histologic Severity of Graft Rejection by Barten, Markus J., Van Gelder, Teun, Gummert, Jan F., Boeke, Katrin, Shorthouse, Randi, Billingham, Margaret E., Morris, Randall E.

“…The primary mechanism of action in vivo of mycophenolate mofetil (MMF) is believed to be inhibition of lymphocyte proliferation. We used novel assays of…”
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Pharmacodynamics of mycophenolic acid in heart allograft recipients: Correlation of lymphocyte proliferation and activation with pharmacokinetics and graft histology by GUMMERT, Jan F, BARTEN, Markus J, VAN GELDER, Teun, BILLINGHAM, Margaret E, MORRIS, Randall E

“…Assays of drug blood levels are used for therapeutic immunosuppressive drug monitoring (pharmacokinetics, PK). We monitored lymphocyte functions…”
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Induction of nitric oxide synthase in the human cardiac allograft is associated with contractile dysfunction of the left ventricle by LEWIS, N. P, TSAO, P. S, BILLINGHAM, M. E, VALANTINE, H. A, FOWLER, M. B, RICKENBACHER, P. R, CHUN XUE, JOHNS, R. A, HAYWOOD, G. A, VON DER LEYEN, H, TRINDADE, P. T, COOKE, J. P, HUNT, S. A

“…The mechanisms underlying cardiac contractile dysfunction after transplantation remain poorly defined. Previous work has revealed that inducible nitric oxide…”
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Incidence of myocarditis in peripartum cardiomyopathy by Rizeq, Mona N., Rickenbacher, Peter R., Fowler, Michael B., Billingham, Margaret E.

“…Peripartum cardiomyopathy (PC), an uncommon cause of pospartum heart failure, is defined as a cardiomyopathy presenting in the last trimester of pregnancy or…”
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Sustained suppression of peripheral blood immune functions by treatment with mycophenolate mofetil correlates with reduced severity of cardiac allograft rejection by Klupp, Jochen, van Gelder, Teun, Dambrin, Camille, Regieli, Jakub J, Boeke, Katrin, Billingham, Margaret E, Morris, Randall E

“…We tested the hypothesis that sustained suppression of immune functions by mycophenolate mofetil (MMF) throughout the dosing interval reduces the severity of…”
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Transplant coronary artery disease: A novel model independent of cellular alloimmune response by CANTIN, Bernard, PEIZHONG WEN, DENING ZHU, DAI, Michelle, PANCHAL, Shyam N, BILLINGHAM, Margaret E, GWATHMEY, Judith K, VALANTINE, Hannah A

“…Allograft coronary atherosclerosis (TxCAD) is the leading cause of death after the first year after transplantation. TxCAD is believed to be a form of chronic…”
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Accuracy of biplane and multiplane transesophageal echocardiography in diagnosis of typical acute aortic dissection and intramural hematoma by Keren, Andre, Kim, Charles B., Hu, Bob S., Eyngorina, Irina, Billingham, Margaret E., Mitchell, R.Scott, Miller, D.Craig, Popp, Richard L., Schnittger, Ingela

“…Objectives. The purpose of this study was to evaluate the diagnostic accuracy of biplane and multiplane transesophageal echocardiography in patients with…”
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Effects of Increased ICAM-1 on Reperfusion Injury and Chronic Graft Vascular Disease by Poston, Robert S, Billingham, Margaret E, Pollard, Jeffrey, Hoyt, E.Grant, Robbins, Robert C

“…Background. The purpose of this study was to assess the impact of increased donor cardiac intercellular adhesion molecule (ICAM-1) expression on both…”
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Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts by Bristow, M R, Ginsburg, R, Minobe, W, Cubicciotti, R S, Sageman, W S, Lurie, K, Billingham, M E, Harrison, D C, Stinson, E B

“…To identify the role of the myocardial beta-adrenergic pathway in congestive heart failure, we examined beta-adrenergic-receptor density, adenylate cyclase and…”
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Cardiac transplantation: The Stanford experience in the cyclosporine era by Sarris, George E., Moore, Kathleen A., Schroeder, John S., Hunt, Sharon A., Fowler, Michael B., Valantine, Hannah B., Vagelos, Randall H., Billingham, Margaret E., Oyer, Philip E., Stinson, Edward B., Reitz, Bruce A., Shumway, Norman E.

“…We analyzed our experience with 496 patients who underwent primary cardiac transplantation since the introduction of cyclosporine immunosuppression (Dec. 16,…”
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Granzyme A and perforin as markers for rejection in cardiac transplantation by Griffiths, G M, Namikawa, R, Mueller, C, Liu, C C, Young, J D, Billingham, M, Weissman, I

“…The use of granzyme A and perforin as markers for rejection after cardiac transplantation has been investigated. Using in situ hybridization we have detected…”
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Heart-lung transplantation: successful therapy for patients with pulmonary vascular disease by Reitz, B A, Wallwork, J L, Hunt, S A, Pennock, J L, Billingham, M E, Oyer, P E, Stinson, E B, Shumway, N E

“…We report our initial experience with three patients who received heart-lung transplants. The primary immunosuppressive agent used was cyclosporin A, although…”
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Dose-effect and structure-function relationships in doxorubicin cardiomyopathy by Bristow, M R, Mason, J W, Billingham, M E, Daniels, J R

“…The cardiomyopathy (CM) produced by the anticancer drug doxorubicin (DXR) (Adriamycin) provides a unique opportunity to analyze dose-effect and…”
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Lipofuscin and Lipid Oxidation in Human Coronary Endothelium by Joris, Isabelle, Billingham, Margaret E, Underwood, Jean M, Majno, Guido

“…Coronary artery endothelium was studied in 13 human hearts removed in the course of heart transplants. Plasma cholesterol ranged from 60 to 240 mg/dl (median…”
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Nodular endocardial infiltrates (Quilty lesions) cause significant variability in diagnosis of ISHLT Grade 2 and 3A rejection in cardiac allograft recipients by Marboe, Charles C, Billingham, Margaret, Eisen, Howard, Deng, Mario C, Baron, Helen, Mehra, Mandeep, Hunt, Sharon, Wohlgemuth, Jay, Mahmood, Irfan, Prentice, James, Berry, Gerald

“…Endomyocardial biopsy is used to guide therapy after heart transplantation. An accurate and reliable diagnosis of rejection is critical for proper patient…”
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The revised ISHLT heart biopsy grading scale by Billingham, Margaret, Kobashigawa, Jon A

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Gene expression profiles and B-type natriuretic peptide elevation in heart transplantation : More than a hemodynamic marker by MEHRA, Mandeep R, UBER, Patricia A, WALTHER, Dirk, VESELY, Mark, WOHLGEMUTH, Jay G, PRENTICE, James, TAYAMA, Darren, BILLINGHAM, Margaret

“…B-type natriuretic peptide (BNP) is chronically elevated in heart transplantation and reflects diastolic dysfunction, cardiac allograft vasculopathy, and poor…”
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