Search Results - "Billingham, L"

Guidelines for preclinical and early phase clinical assessment of novel radiosensitisers by Harrington, K J, Billingham, L J, Brunner, T B, Burnet, N G, Chan, C S, Hoskin, P, Mackay, R I, Maughan, T S, Macdougall, J, McKenna, W G, Nutting, C M, Oliver, A, Plummer, R, Stratford, I J, Illidge, T

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Traveling Foreshocks and Transient Foreshock Phenomena by Kajdič, P., Blanco‐Cano, X., Omidi, N., Rojas‐Castillo, D., Sibeck, D. G., Billingham, L.

“…We use the multispacecraft capabilities of the Cluster and Time History of Events and Macroscale Interactions during Substorms (THEMIS) missions to show that…”
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Identification of serum biomarkers for colon cancer by proteomic analysis by WARD, D. G, SUGGETT, N, CHENG, Y, WEI, W, JOHNSON, H, BILLINGHAM, L. J, ISMAIL, T, WAKELAM, M. J. O, JOHNSON, P. J, MARTIN, A

“…Colorectal cancer (CRC) is often diagnosed at a late stage with concomitant poor prognosis. Early detection greatly improves prognosis; however, the invasive,…”
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Effect of topical imiquimod as primary treatment for lentigo maligna: the LIMIT‐1 study by Marsden, J.R., Fox, R., Boota, N.M., Cook, M., Wheatley, K., Billingham, L.J., Steven, N.M., Simpkins, D., Whitham, D., Chalmers, J., Bunker, C., Wharton, S., Brothwell, S., Hague, L., Harwood, C., Ives, N., Ramsay, H., Burrows, L., Proby, C., Motley, R., Levell, N., Lucke, T., Zaki, I., Gupta, G., Collucci, L., Williams, J., Steele, J.

“…Summary Background Topical imiquimod is sometimes used for lentigo maligna (LM) in situ melanoma instead of surgery, but frequency of cure is uncertain…”
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The National Lung Matrix Trial: translating the biology of stratification in advanced non-small-cell lung cancer by Middleton, G., Crack, L.R., Popat, S., Swanton, C., Hollingsworth, S.J., Buller, R., Walker, I., Carr, T.H., Wherton, D., Billingham, L.J.

“…The management of NSCLC has been transformed by stratified medicine. The National Lung Matrix Trial (NLMT) is a UK-wide study exploring the activity of…”
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Modelling prognostic factors in advanced pancreatic cancer by Stocken, D D, Hassan, A B, Altman, D G, Billingham, L J, Bramhall, S R, Johnson, P J, Freemantle, N

“…Pancreatic cancer is the fifth most common cause of cancer death. Identification of defined patient groups based on a prognostic index may improve the…”
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Pembrolizumab in performance status 2 patients with non-small cell lung cancer (NSCLC): Results of the PePS2 trial by Middleton, G., Brock, K., Summers, Y., Connibear, J., Shah, R., Ottensmeier, C., Shaw, P., Ming-Lee, S., Popat, S., Barrie, C., Barone, G., Mant, R., Savage, J.S., Billingham, L.

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Folic acid supplementation in postmenopausal women with hot flushes: phase III randomised double‐blind placebo‐controlled trial by Ewies, AAA, Ahmed, I, Al‐Azzawi, F, Pitkin, J, Gupta, P, Persic, M, Sahu, B, Elgobashy, A, Barraclough, L, Woodman, J, Babrah, J, Bowden, S, Stocken, D, Billingham, L, Sundar, S, Rea, D

“…Objective To assess whether folic acid supplementation ameliorates hot flushes. Design Double‐blind, placebo‐controlled randomised trial. Setting Nine…”
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Patient preferences for clinical follow-up after primary treatment for soft tissue sarcoma: A cross-sectional survey and discrete choice experiment by Damery, S, Biswas, M, Billingham, L, Barton, P, Al-Janabi, H, Grimer, R

“…Abstract Background Patients treated for soft tissue sarcoma (STS) require long-term follow-up to detect recurrent or metastatic disease, yet marked…”
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Mitomycin, Ifosfamide, and Cisplatin in Unresectable Non–Small-Cell Lung Cancer: Effects on Survival and Quality of Life by CULLEN, M. H, BILLINGHAM, L. J, TRASK, C, BESSELL, E, CONNOLLY, C. K, TOBIAS, J, SOUHAMI, R. L, WOODROFFE, C. M, CHETIYAWARDANA, A. D, GOWER, N. H, JOSHI, R, FERRY, D. R, RUDD, R. M, SPIRO, S. G, COOK, J. E

“…Chemotherapy for non-small-cell lung cancer (NSCLC) remains controversial. We describe the two largest reported, randomized, parallel trials designed to…”
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Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer by HUSSAIN, S. A, GANESAN, R, JAMES, N. D, SPOONER, D, POOLE, Cj, REA, D. W, PALMER, D. H, REYNOLDS, G, GROSS, L, STEVENS, A, PASTOREK, J, MURRAY, P. G, PERUNOVIC, B, ANWAR, M. S, BILLINGHAM, L

“…Tumour hypoxia is a microenvironmental factor related to poor response to radiation, chemotherapy, genetic instability, selection for resistance to apoptosis,…”
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Phase I II trial of a dendritic cell vaccine transfected with DNA encoding melan A and gp100 for patients with metastatic melanoma by Steele, J C, Rao, A, Marsden, J R, Armstrong, C J, Berhane, S, Billingham, L J, Graham, N, Roberts, C, Ryan, G, Uppal, H, Walker, C, Young, L S, Steven, N M

“…This trial tested a dendritic cell (DC) therapeutic cancer vaccine in which antigen is loaded using a novel non-viral transfection method enabling the uptake…”
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Changes in the serum proteome associated with the development of hepatocellular carcinoma in hepatitis C-related cirrhosis by WARD, D. G, CHENG, Y, N'KONTCHOU, G, THAR, T. T, BARGET, N, WEI, W, BILLINGHAM, L. J, MARTIN, A, BEAUGRAND, M, JOHNSON, P. J

“…Early diagnosis of hepatocellular carcinoma (HCC) is the key to the delivery of effective therapies. The conventional serological diagnostic test, estimation…”
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Analysis of phase II methodologies for single-arm clinical trials with multiple endpoints in rare cancers: An example in Ewing’s sarcoma by Dutton, P, Love, SB, Billingham, L, Hassan, AB

“…Trials run in either rare diseases, such as rare cancers, or rare sub-populations of common diseases are challenging in terms of identifying, recruiting and…”
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186: Forecasting patient recruitment for time-to-event analysis in National Lung Matrix Trial by Brock, K, Billingham, L, Crack, L, Popat, S, Middleton, G

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187: National Lung Matrix Trial: multi-drug, genetic marker-directed, non-comparative, multi-centre, multi-arm phase II trial in non-small cell lung cancer by Middleton, G, Billingham, L, Crack, L, Popat, S, Walker, I

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Vortex Trial: A Randomized Controlled Multicenter Phase 3 Trial of Volume of Postoperative Radiation Therapy Given to Adult Patients With Extremity Soft Tissue Sarcoma (STS) by Robinson, M.H, Gaunt, P, Grimer, R, Seddon, B, Wylie, J, Davis, A, Hughes, D, Peake, D, Cassoni, A, Spooner, D, Miah, A, Hughes, A, West, C.M.L, Venables, K, Billingham, L

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3434 A UK national phase I/II clinical trial of a MEK1/2 inhibitor combined with highly active anti-retroviral therapy for HIV-associated Kaposi's sarcoma by Young, R, Poyser, C, Crack, L, Dockrell, D, Bowman, C, Billingham, L, Bower, M, Westwell, S, Leahy, M, Woll, P

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Hot flow anomalies at Saturn's bow shock by Masters, A., McAndrews, H. J., Steinberg, J. T., Thomsen, M. F., Arridge, C. S., Dougherty, M. K., Billingham, L., Schwartz, S. J., Sergis, N., Hospodarsky, G. B., Coates, A. J.

“…We present evidence for the occurrence of hot flow anomalies (HFAs) at Saturn's bow shock. A survey of Cassini magnetic field and electron data taken upstream…”
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The statistics of foreshock cavities : results of a Cluster survey by BILLINGHAM, L, SCHWARTZ, S. J, SIBECK, D. G

“…We use Cluster magnetic field, thermal ion, and energetic particle observations upstream of the Earth's bow shock to investigate the occurrence patterns of…”
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