Search Results - "Bille Jendresen, Christian"

Production of zosteric acid and other sulfated phenolic biochemicals in microbial cell factories by Jendresen, Christian Bille, Nielsen, Alex Toftgaard

“…Biological production and application of a range of organic compounds is hindered by their limited solubility and toxicity. This work describes a process for…”
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Highly Active and Specific Tyrosine Ammonia-Lyases from Diverse Origins Enable Enhanced Production of Aromatic Compounds in Bacteria and Saccharomyces cerevisiae by Jendresen, Christian Bille, Stahlhut, Steen Gustav, Li, Mingji, Gaspar, Paula, Siedler, Solvej, Förster, Jochen, Maury, Jérôme, Borodina, Irina, Nielsen, Alex Toftgaard

“…Phenylalanine and tyrosine ammonia-lyases form cinnamic acid and p-coumaric acid, which are precursors of a wide range of aromatic compounds of…”
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Injection molded lab-on-a-disc platform for screening of genetically modified E. coli using liquid-liquid extraction and surface enhanced Raman scattering by Morelli, Lidia, Serioli, Laura, Centorbi, Francesca Alessandra, Jendresen, Christian Bille, Matteucci, Marco, Ilchenko, Oleksii, Demarchi, Danilo, Nielsen, Alex Toftgaard, Zór, Kinga, Boisen, Anja

“…We present the development of an automated centrifugal microfluidic platform with integrated sample pre-treatment (filtration and liquid-liquid extraction) and…”
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Enhanced protein and biochemical production using CRISPRi-based growth switches by Li, Songyuan, Jendresen, Christian Bille, Grünberger, Alexander, Ronda, Carlotta, Jensen, Sheila Ingemann, Noack, Stephan, Nielsen, Alex Toftgaard

“…Production of proteins and biochemicals in microbial cell factories is often limited by carbon and energy spent on excess biomass formation. To address this…”
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Lab-on-a-disc platform for screening of genetically modified E. coli cells via cell-free electrochemical detection of p-Coumaric acid by Sanger, Kuldeep, Zór, Kinga, Bille Jendresen, Christian, Heiskanen, Arto, Amato, Letizia, Toftgaard Nielsen, Alex, Boisen, Anja

“…•Lab-on-a-disc device was developed for screening of genetically modified strains.•p-Coumaric acid was measured using electrodes fabricated on plastic…”
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Increasing production yield of tyrosine and mevalonate through inhibition of biomass formation by Li, Songyuan, Jendresen, Christian Bille, Nielsen, Alex Toftgaard

“…[Display omitted] •Reduction of E. coli biomass formation results in higher product yield and titer.•Effect of nutrient limitation and growth inhibitors were…”
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Genetic toolbox for controlled expression of functional proteins in Geobacillus spp by Pogrebnyakov, Ivan, Jendresen, Christian Bille, Nielsen, Alex Toftgaard

“…Species of genus Geobacillus are thermophilic bacteria and play an ever increasing role as hosts for biotechnological applications both in academia and…”
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Quantification of a bacterial secondary metabolite by SERS combined with SLM extraction for bioprocess monitoring by Morelli, Lidia, Andreasen, Sune Zoëga, Jendresen, Christian Bille, Nielsen, Alex Toftgaard, Emnéus, Jenny, Zór, Kinga, Boisen, Anja

“…During the last few decades, great advances have been reached in high-throughput design and building of genetically engineered microbial strains, leading to a…”
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Optics miniaturization strategy for demanding Raman spectroscopy applications by Ilchenko, Oleksii, Pilhun, Yurii, Kutsyk, Andrii, Slobodianiuk, Denys, Goksel, Yaman, Dumont, Elodie, Vaut, Lukas, Mazzoni, Chiara, Morelli, Lidia, Boisen, Sofus, Stergiou, Konstantinos, Aulin, Yaroslav, Rindzevicius, Tomas, Andersen, Thomas Emil, Lassen, Mikael, Mundhada, Hemanshu, Jendresen, Christian Bille, Philipsen, Peter Alshede, Hædersdal, Merete, Boisen, Anja

“…Raman spectroscopy provides non-destructive, label-free quantitative studies of chemical compositions at the microscale as used on NASA’s Perseverance rover on…”
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CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae by Jakočiu̅nas, Tadas, Rajkumar, Arun S, Zhang, Jie, Arsovska, Dushica, Rodriguez, Angelica, Jendresen, Christian Bille, Skjødt, Mette L, Nielsen, Alex T, Borodina, Irina, Jensen, Michael K, Keasling, Jay D

“…Homologous recombination (HR) in Saccharomyces cerevisiae has been harnessed for both plasmid construction and chromosomal integration of foreign DNA. Still,…”
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Surface Enhanced Raman Scattering for Quantification of p‑Coumaric Acid Produced by Escherichia coli by Morelli, Lidia, Zór, Kinga, Jendresen, Christian Bille, Rindzevicius, Tomas, Schmidt, Michael Stenbæk, Nielsen, Alex Toftgaard, Boisen, Anja

“…The number of newly developed genetic variants of microbial cell factories for production of biochemicals has been rapidly growing in recent years, leading to…”
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Simultaneous quantification of multiple bacterial metabolites using surface-enhanced Raman scattering by Morelli, Lidia, Centorbi, Francesca Alessandra, Ilchenko, Oleksii, Jendresen, Christian Bille, Demarchi, Danilo, Nielsen, Alex Toftgaard, Zór, Kinga, Boisen, Anja

“…Given the commercial importance of the compounds produced by genetically modified organisms, there is a need for screening methods which facilitate the…”
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The PurR regulon in Lactococcus lactis ― transcriptional regulation of the purine nucleotide metabolism and translational machinery by JENDRESEN, Christian Bille, MARTINUSSEN, Jan, KILSTRUP, Mogens

“…Purine nucleotides are either synthesized de novo from 5-phosphoribosyl-1-pyrophosphate (PRPP) or salvaged from the environment. In Lactococcus lactis,…”
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Two nucleoside transporters in Lactococcus lactis with different substrate specificities by MARTINUSSEN, Jan, SØRENSEN, Claus, BILLE JENDRESEN, Christian, KILSTRUP, Mogens

“…In an alternative to biosynthesis of nucleotides, most organisms are capable of exploiting exogenous nucleotide sources. In order to do so, the nucleotide…”
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Characterization of tyrosine ammonia lyases from Flavobacterium johnsonian and Herpetosiphon aurantiacus by Virklund, Alexander, Jendresen, Christian Bille, Nielsen, Alex Toftgaard, Woodley, John M

“…p-Coumaric acid (pCA) can be produced via bioprocessing and is a promising chemical precursor to making organic thin film transistors. However, the required…”
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Characterization of tyrosine ammonia lyases from Flavobacterium johnsoniae and Herpetosiphon aurantiacus by Virklund, Alexander, Jendresen, Christian Bille, Nielsen, Alex Toftgaard, Woodley, John M.

“…p‐Coumaric acid (pCA) can be produced via bioprocessing and is a promising chemical precursor to making organic thin film transistors. However, the required…”
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Genome-Wide CRISPRi-Based Identification of Targets for Decoupling Growth from Production by Li, Songyuan, Jendresen, Christian Bille, Landberg, Jenny, Pedersen, Lasse Ebdrup, Sonnenschein, Nikolaus, Jensen, Sheila Ingemann, Nielsen, Alex Toftgaard

“…Growth decoupling can be used to optimize microbial production of biobased compounds by inhibiting excess biomass formation and redirect carbon flux from…”
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A simplified method for rapid quantification of intracellular nucleoside triphosphates by one-dimensional thin-layer chromatography by Jendresen, Christian Bille, Kilstrup, Mogens, Martinussen, Jan

“…Quantification of nucleotides is an important part of metabolomics but has been hampered by the lack of fast, sensitive, and reliable methods. We present a…”
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Towards in vivo regulon kinetics: PurR activation by 5-phosphoribosyl-α-1-pyrophosphate during purine depletion in Lactococcus lactis by Jendresen, Christian Bille, Dimitrov, Peter, Gautier, Laurent, Liu, Meng, Martinussen, Jan, Kilstrup, Mogens

“…Short-term adaptation to changing environments relies on regulatory elements translating shifting metabolite concentrations into a specifically optimized…”
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Extraction, Enrichment, and in situ Electrochemical Detection on Lab-on-a-Disc: Monitoring the Production of a Bacterial Secondary Metabolite by Andreasen, Sune Zoëga, Sanger, Kuldeep, Jendresen, Christian Bille, Nielsen, Alex Toftgaard, Emnéus, Jenny, Boisen, Anja, Zór, Kinga

“…Development of microsystems, which enable “sample-to-answer” detection from real samples, is often challenging. We present the first integration of supported…”
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