Search Results - "Billauer, Hana"
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A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism
Published in Cancer cell (12-08-2013)“…Senescence, perceived as a cancer barrier, is paradoxically associated with inflammation, which promotes tumorigenesis. Here, we characterize a distinct…”
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Modified PEG-anilinoquinazoline derivatives as potential EGFR PET agents
Published in Journal of labelled compounds & radiopharmaceuticals (01-02-2009)“…Inhibition of epidermal growth factor receptor tyrosine kinase (EGFR‐TK) has emerged as a major approach for cancer‐targeted therapy. Consequently, there has…”
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Abstract 4609: Plixorafenib (plixo) synergizes with MEK inhibitors (MEKi) in MAPK pathway inhibition in BRAF V600 and non V600 alterations, with higher potency compared to early generation BRAFi and pan-RAFi
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…The efficacy of BRAFi in V600 mutated tumors is established and requires effective inhibition of the MAPK pathway. However, the use approved BRAFi leads to…”
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Labeled 3-aryl-4-indolylmaleimide derivatives and their potential as angiogenic PET biomarkers
Published in Bioorganic & medicinal chemistry (15-01-2010)“…New 3-aryl-4-indolylmaleimide derivatives were synthesized and evaluated as potential PET biomarkers for monitoring angiogenic processes. In a continued effort…”
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A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism
Published in Cancer cell (08-06-2015)Get full text
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Antihyperglycaemic activity of 2,4:3,5‐dibenzylidene‐D‐xylose‐diethyl dithioacetal in diabetic mice
Published in Journal of cellular and molecular medicine (01-03-2012)“…We have recently generated lipophilic D‐xylose derivatives that increase the rate of glucose uptake in cultured skeletal muscle cells in an AMP‐activated…”
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Structure–Activity Relationship and Preclinical Evaluation of Carbon-11-Labeled Ammonium Salts as PET–Myocardial Perfusion Imaging Agents
Published in Molecular imaging and biology (01-10-2012)“…Background Due to the limited availability of suitable positron emission tomography (PET) tracers, the majority of myocardial perfusion imaging (MPI) scans is…”
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Novel and Simple Carbon-11-Labeled Ammonium Salts as PET Agents for Myocardial Perfusion Imaging
Published in Molecular imaging and biology (01-02-2011)“…Background Positron emission tomography (PET) has clear advantages over single photon emission computed tomography (SPECT) in the field of myocardial perfusion…”
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Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation
Published in Behavioural brain research (28-12-2009)“…Identifying the mechanisms underlying the adverse effects of developmental neurotoxicants enables the design of therapies that can potentially reverse…”
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