Search Results - "Billaud, M"
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Antifungal Drugs TDM: Trends and Update
Published in Therapeutic drug monitoring (01-02-2022)“…The increasing burden of invasive fungal infections results in growing challenges to antifungal (AF) therapeutic drug monitoring (TDM). This review aims to…”
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Dried Urine Spot Analysis for assessing cardiovascular drugs exposure applicable in spaceflight conditions
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-03-2023)“…•Dried urine spot as an alternative to urine sampling in extreme conditions particularly during spaceflight missions.•A method was developed to detect 5…”
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Clinical Relevance of the Pharmacokinetic Interactions of Azole Antifungal Drugs with Other Coadministered Agents
Published in Clinical infectious diseases (15-05-2009)“…There are currently a number of licensed azole antifungal drugs; however; only 4 (namely, fluconazole, itraconazole, posaconazole, and voriconazole) are used…”
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Clinical risk factors for invasive aspergillosis in lung transplant recipients: Results of an international cohort study
Published in The Journal of heart and lung transplantation (01-10-2018)“…Invasive aspergillosis (IA) is a frequent complication in lung transplant recipients (LTRs). Clinical risk factors for IA have not been fully characterized,…”
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The 2015 International Society for Heart and Lung Transplantation Guidelines for The Management of Fungal Infections in Mechanical Circulatory Support and Cardiothoracic Organ Transplant Recipients: Executive Summary
Published in The Journal of heart and lung transplantation (01-03-2016)Get full text
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Interaction between nitric oxide signaling and gap junctions: Effects on vascular function
Published in Biochimica et biophysica acta (01-08-2012)“…Nitric oxide signaling, through eNOS (or possibly nNOS), and gap junction communication are essential for normal vascular function. While each component…”
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Pharmacokinetics of antifungal agents in neonates and young infants
Published in Current medicinal chemistry (01-09-2012)“…The prevention and treatment of pediatric fungal infections are limited by the fact that not all antifungal drugs are approved for the pediatric age and…”
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Micro-flow photosynthesis of new dienophiles for inverse-electron-demand Diels-Alder reactions. Potential applications for pretargeted in vivo PET imaging
Published in Chemical science (Cambridge) (01-02-2017)“…Pretargeted PET imaging has emerged as an effective two-step approach that combines the superior affinity and selectivity of antibodies with the rapid…”
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Therapeutic drug monitoring for triazoles
Published in Current opinion in infectious diseases (01-12-2008)“…PURPOSE OF REVIEWInvasive fungal infections are a leading cause of morbidity and mortality in immunocompromised patients, and mechanisms to optimize…”
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Synthesis, Radiofluorination, and in Vivo Evaluation of Novel Fluorinated and Iodinated Radiotracers for PET Imaging and Targeted Radionuclide Therapy of Melanoma
Published in Journal of medicinal chemistry (14-11-2013)“…Our project deals with a multimodal approach using a single fluorinated and iodinated melanin-targeting structure and offering both imaging (positron emission…”
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A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties
Published in Oncogene (30-04-2015)“…The LKB1 tumor suppressor gene encodes a master kinase that coordinates the regulation of energetic metabolism and cell polarity. We now report the…”
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Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1
Published in Oncogene (22-03-2012)“…LKB1 is a tumor suppressor that is constitutionally mutated in a cancer-prone condition, called Peutz-Jeghers syndrome, as well as somatically inactivated in a…”
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Effect of cytochrome P450 2C19 genotype on voriconazole exposure in cystic fibrosis lung transplant patients
Published in European journal of clinical pharmacology (01-03-2011)“…Purpose Voriconazole is widely used to treat invasive aspergillosis after lung transplantation. In cystic fibrosis patients, the interindividual variability in…”
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Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies
Published in Nucleic acids research (01-02-2007)“…In Caenorhabditis elegans, the Mex-3 protein is a translational regulator that specifies the posterior blastomere identity in the early embryo and contributes…”
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Expression of calcineurin activity after lung transplantation: a 2-year follow-up
Published in PloS one (25-03-2013)“…The objective of this pharmacodynamic study was to longitudinally assess the activity of calcineurin during the first 2 years after lung transplantation. From…”
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Factors for Hematopoietic Toxicity of Carboplatin: Refining the Targeting of Carboplatin Systemic Exposure
Published in Journal of clinical oncology (20-10-2010)“…Area under the curve (AUC) dosing is routinely carried out for carboplatin, but the chosen target AUC values remain largely empirical. This multicenter…”
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BRCA1 Affects Lipid Synthesis through Its Interaction with Acetyl-CoA Carboxylase
Published in The Journal of biological chemistry (10-02-2006)“…Germ line alterations in BRCA1 (breast cancer susceptibility gene 1) are associated with an increased susceptibility to breast and ovarian cancer. BRCA1 acts…”
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Rational molecular assessment and innovative drug selection (RAIDs): Pharmacological profiling of 20 cervical cancer cell lines
Published in European journal of cancer (1990) (01-12-2016)“…An abstract of the study by Kamal et al evaluating large-scale pharmacological screenings of cancer cell lines to enlarge cancer treatment options is…”
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Theranostic Approach for Metastatic Pigmented Melanoma Using ICF15002, a Multimodal Radiotracer for Both PET Imaging and Targeted Radionuclide Therapy
Published in Neoplasia (New York, N.Y.) (01-01-2017)“…Abstract PURPOSE: This work reports, in melanoma models, the theranostic potential of ICF15002 as a single fluorinated and iodinated melanin-targeting…”
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Docking Protein FRS2 Links the Protein Tyrosine Kinase RET and Its Oncogenic Forms with the Mitogen-Activated Protein Kinase Signaling Cascade
Published in Molecular and Cellular Biology (01-07-2001)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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