Search Results - "Bilham, Kirstin"

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity by Becker, Jordan R., Cuella-Martin, Raquel, Barazas, Marco, Liu, Rui, Oliveira, Catarina, Oliver, Antony W., Bilham, Kirstin, Holt, Abbey B., Blackford, Andrew N., Heierhorst, Jörg, Jonkers, Jos, Rottenberg, Sven, Chapman, J. Ross

“…53BP1 controls a specialized non-homologous end joining (NHEJ) pathway that is essential for adaptive immunity, yet oncogenic in BRCA1 mutant cancers…”
Get full text

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ by Ghezraoui, Hind, Oliveira, Catarina, Becker, Jordan R., Bilham, Kirstin, Moralli, Daniela, Anzilotti, Consuelo, Fischer, Roman, Deobagkar-Lele, Mukta, Sanchiz-Calvo, Maria, Fueyo-Marcos, Elena, Bonham, Sarah, Kessler, Benedikt M., Rottenberg, Sven, Cornall, Richard J., Green, Catherine M., Chapman, J. Ross

“…53BP1 governs a specialized, context-specific branch of the classical non-homologous end joining DNA double-strand break repair pathway. Mice lacking 53bp1…”
Get full text

In situ behavioral plasticity as compensation for weather variability: implications for future climate change by Noonan, Michael J., Newman, Chris, Markham, Andrew, Bilham, Kirstin, Buesching, Christina D., Macdonald, David W.

“…While climatic effects on species biogeographic distributions are well documented, less mobile species must compensate for climate change in situ via…”
Get full text

Effects of Weather Conditions on Oxidative Stress, Oxidative Damage, and Antioxidant Capacity in a Wild-Living Mammal, the European Badger (Meles meles) by Bilham, Kirstin, Newman, Chris, Buesching, Christina D., Noonan, Michael J., Boyd, Amy, Smith, Adrian L., Macdonald, David W.

“…Wild-living animals are subject to weather variability that may cause the generation of reactive oxygen species, resulting in oxidative stress and tissue…”
Get full text

Badger macrophages fail to produce nitric oxide, a key anti-mycobacterial effector molecule by Bilham, Kirstin, Boyd, Amy C., Preston, Stephen G., Buesching, Christina D., Newman, Chris, Macdonald, David W., Smith, Adrian L.

“…The European badger is recognised as a wildlife reservoir for bovine tuberculosis (bTB); the control of which is complex, costly and controversial. Despite the…”
Get full text

The effects of oxidative stress and innate immunity on european badger (meles meles) life-history dynamics by Bilham, Kirstin Louise

“…Wild animals are faced with many stressors from starvation to infections, which will affect individual survival and population dynamics. Free radicals and…”
Get full text