Search Results - "Bilginer, Sinan"

New benzamide derivatives and their nicotinamide/cinnamamide analogs as cholinesterase inhibitors by Koca, Mehmet, Bilginer, Sinan

“…In this study, a total of 18 new benzamide/ nicotinamide/ cinnamamide derivative compounds were designed and synthesized for the first time (except B1 and B5)…”
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Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties by Bilginer, Sinan, Gonder, Baris, Gul, Halise Inci, Kaya, Ruya, Gulcin, Ilhami, Anil, Baris, Supuran, Claudiu T.

“…A series of compounds incorporating 3-(3-(2/3/4-substituted phenyl)triaz-1-en-1-yl) benzenesulfonamide moieties were synthesised and their chemical structure…”
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Evaluation of antioxidant potentials and acetylcholinesterase inhibitory effects of some new salicylic acid-salicylamide hybrids by Koca, Mehmet, Gülçin, İlhami, Üç, Eda Mehtap, Bilginer, Sinan, Aydın, Amine Sena

“…Antioxidants are used in foods, drugs, and many products such as cosmetics to prevent the formation of toxic radicals resulting from oxidation. It is thought…”
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Synthesis, cytotoxicities, and carbonic anhydrase inhibition activities of pyrazoline–benzenesulfonamide derivatives harboring phenol/polyphenol moieties by Bilginer, Sinan, Bardaweel, Sanaa K., Demir, Yeliz, Gulcin, Ilhami, Kazaz, Cavit

“…In this study, phenol and benzenesulfonamide substituted pyrazoline derivative novel compounds ( 1a–14a ) were synthesized successfully for the first time…”
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Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones by Bilginer, Sinan, Gul, Halise Inci, Erdal, Feyza Sena, Sakagami, Hiroshi, Levent, Serkan, Gulcin, Ilhami, Supuran, Claudiu T.

“…In this study, new chalcone compounds having the chemical structure of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones (1-8) were synthesised and were…”
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Oleuropein and Verbascoside - Their Inhibition Effects on Carbonic Anhydrase and Molecular Docking Studies by Aggul, Ahmet Gokhan, Taslimi, Parham, Kuzu, Muslum, Uzun, Naim, Bilginer, Sinan, Gulcin, Ilhami

“…Recently, carbonic anhydrase (CA, E.C.4.2.1.1) inhibitors from natural product have paved the way for novel drug design in the treatment and prevention of some…”
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Crystal structure of 4-[5-(4-fluorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydropyrazol-1-yl] benzenesulfonamide, C21H18FN3O3S by Aydın, Abdullah, Bilginer, Sinan, Gul, Halise Inci, Akkurt, Mehmet, Mete, Ebru

“…FN S, monoclinic, 2 (no. 4), = 11.6665(3) Å, = 5.7483(2) Å, = 14.7695(4) Å, α = 90°, = 103.841(1)°, = 90°, = 961.72(5) Å , = 2, = 0.0340, = 0.0852, = 296(2) K…”
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Synthesis and antifungal evaluation of 1-aryl-2-dimethyl- aminomethyl-2-propen-1-one hydrochlorides by Mete, Ebru, Gul, Halise Inci, Bilginer, Sinan, Algul, Oztekin, Topaloglu, Mehmet Emin, Gulluce, Medine, Kazaz, Cavit

“…The development of resistance to current antifungal therapeutics drives the search for new effective agents. The fact that several acetophenone-derived Mannich…”
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Synthesis and in silico studies of triazene‐substituted sulfamerazine derivatives as acetylcholinesterase and carbonic anhydrases inhibitors by Bilginer, Sinan, Gul, Halise I., Anil, Baris, Demir, Yeliz, Gulcin, Ilhami

“…A novel series of sulfonamides, 4‐(3‐phenyltriaz‐1‐en‐1‐yl)‐N‐(4‐methyl‐2‐pyrimidinyl)benzenesulfonamides (1–9), was designed and synthesized by the diazo…”
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Molecular Docking Study of Several Seconder Metabolites from Medicinal Plants as Potential Inhibitors of COVID-19 Main Protease by Bilginer, Sinan, Gözcü, Sefa, Güvenalp, Zuhal

“…ObjectivesCoronaviruses (CoVs) cause infections that affect the respiratory tract, liver, central nervous, and the digestive systems in humans and animals…”
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Novel Mannich bases with strong carbonic anhydrases and acetylcholinesterase inhibition effects: 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2(3H)-benzoxazolones by BiLGiNER, Sinan, Anil, Barış, Koca, Mehmet, Demir, Yeliz, Gülçin, İlhami

“…In this study, a new series of Mannich bases, 3-(aminomethyl)-6-{3-[4-(trifluoromethyl)phenyl]acryloyl}-2( )-benzoxazolones ( ), were synthesized by the…”
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Antibacterial and Acetylcholinesterase Inhibitory Potentials of Triazenes Containg Sulfonamide Moiety by Bilginer, Sinan, Gul, Halise Inci, Hanci, Hayrunisa, Gulcin, Ilhami

“…The aim of this study was to investigate the antibacterial and acetylcholinesterase (AChE) inhibitory activities of 3-(3-(2/3/4-substituted…”
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Synthesis of 4-(2-substituted hydrazinyl)benzenesulfonamides and their carbonic anhydrase inhibitory effects by Gul, Halise Inci, Kucukoglu, Kaan, Yamali, Cem, Bilginer, Sinan, Yuca, Hafize, Ozturk, Iknur, Taslimi, Parham, Gulcin, Ilhami, Supuran, Claudiu T

“…In this study, 4-(2-substituted hydrazinyl)benzenesulfonamides were synthesized by microwave irradiation and their chemical structures were confirmed by (1)H…”
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New halogenated chalcones with cytotoxic and carbonic anhydrase inhibitory properties: 6‐(3‐Halogenated phenyl‐2‐propen‐1‐oyl)‐2(3H)‐benzoxazolones by Bilginer, Sinan, Gul, Halise I., Erdal, Feyza S., Sakagami, Hiroshi, Gulcin, Ilhami

“…In this study, novel halogenated chalcones, 6‐(3‐halogenated phenyl‐2‐propen‐1‐one)‐2(3H)‐benzoxazolones (2a–n), were synthesized for the first time (except…”
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Phenothiazine‐based chalcones as potential dual‐target inhibitors toward cholinesterases (AChE, BuChE) and monoamine oxidases (MAO‐A, MAO‐B) by Yamali, Cem, Engin, Feyza Sena, Bilginer, Sinan, Tugrak, Mehtap, Ozmen Ozgun, Dilan, Ozli, Gulsen, Levent, Serkan, Saglik, Begum Nurpelin, Ozkay, Yusuf, Gul, Halise Inci

“…Chalcones targeting neurodegenerative diseases have been known as attractive structures in drug design and discovery. In this study, phenothiazine‐based…”
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1-(3-aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones: a novel group of tumour-selective cytotoxins by Bilginer, Sinan, Gul, Halise Inci, Mete, Ebru, Das, Umashankar, Sakagami, Hiroshi, Umemura, Naoki, Dimmock, Jonathan Richard

“…Two series of 1-(3-aminomethyl-4-hydroxyphenyl)-3-pyridinyl-2-propen-1-ones, designed as novel cytotoxins, were synthesized. The compounds had low CC50 values…”
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Carbonic anhydrase inhibitors. Phenols incorporating 2- or 3-pyridyl-ethenylcarbonyl and tertiary amine moieties strongly inhibit Saccharomyces cerevisiae β-carbonic anhydrase by Bilginer, Sinan, Unluer, Elif, Gul, Halise Inci, Mete, Ebru, Isik, Semra, Vullo, Daniela, Ozensoy-Guler, Ozen, Beyaztas, Serap, Capasso, Clemente, Supuran, Claudiu T

“…A series of phenols incorporating tertiary amine and trans-pyridylethenyl-carbonyl moieties were assayed as inhibitors of the β-carbonic anhydrase (CA, EC…”
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Crystal structure of 4-[5-(4-fluorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydropyrazol-1-yl] benzenesulfonamide, C 21 H 18 FN 3 O 3 S by Aydın, Abdullah, Bilginer, Sinan, Gul, Halise Inci, Akkurt, Mehmet, Mete, Ebru

“…C 21 H 18 FN 3 O 3 S, monoclinic, P 2 1 (no. 4), a = 11.6665(3) Å, b = 5.7483(2) Å, c = 14.7695(4) Å, α = 90°, β = 103.841(1)°, γ = 90°, V = 961.72(5) Å 3 , Z…”
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