Search Results - "Bilbe, G."

Region-specific transcriptional changes following the three antidepressant treatments electro convulsive therapy, sleep deprivation and fluoxetine by CONTI, B, MAIER, R, BARR, A. M, MORALE, M. C, LU, X, SANNA, P. P, BILBE, G, HOYER, D, BARTFAI, T

“…The significant proportion of depressed patients that are resistant to monoaminergic drug therapy and the slow onset of therapeutic effects of the selective…”
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Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone by Inaoka, T., Bilbe, G., Ishibashi, O., Tezuka, K., Kumegawa, M., Kokubo, T.

“…We have previously cloned a rabbit cDNA clone (OC-2) from an osteoclast cDNA library by the differential screening. OC-2 was found to encode a novel cysteine…”
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Extracellular nucleotide signaling: a mechanism for integrating local and systemic responses in the activation of bone remodeling by Bowler, W.B, Buckley, K.A, Gartland, A, Hipskind, R.A, Bilbe, G, Gallagher, J.A

“…Bone turnover occurs at discreet sites in the remodeling skeleton. The focal nature of this process indicates that local cues may facilitate the activation of…”
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Localization of cathepsin K in human osteoclasts by in situ hybridization and immunohistochemistry by Littlewood-Evans, A., Kokubo, T., Ishibashi, O., Inaoka, T., Wlodarski, B., Gallagher, J.A., Bilbe, G.

“…We have recently cloned cathepsin K from a human bone cDNA library. Since cathepsins are proposed to be involved in the degradation of mineralized bone matrix,…”
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Formoterol and isoproterenol induce c-fos gene expression in osteoblast-like cells by activating β2-Adrenergic receptors by KELLENBERGER, S, MULLER, K, RICHENER, H, BILBE, G

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PCR phenotyping of cytokines, growth factors and their receptors and bone matrix proteins in human osteoblast-like cell lines by Bilbe, G., Roberts, E., Birch, M., Evans, D.B.

“…The expression of a total of 58 cytokines, growth factors, and their corresponding receptors and bone matrix proteins was assessed using reverse…”
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Parathyroid hormone potentiates nucleotide-induced [Ca2+](i) release in rat osteoblasts independently of G(q) activation or cyclic monophosphate accumulation - A mechanism for localizing systemic responses in bone by Buckley, K. A., Wagstaff, S. C., Mckay, G., Gaw, A., Hipskind, R. A., Bilbe, G., Gallagher, J. A., Bowler, W. B.

“…The regulation of tissue turnover requires the coordinated activity of both local and systemic factors. Nucleotides exist transiently in the extracellular…”
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Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis by Schmid, P, Cox, D, Bilbe, G, Maier, R, McMaster, G K

“…We have examined by Northern analysis and in situ hybridisation the expression of TGF beta 1, beta 2 and beta 3 during mouse embryogenesis. TGF beta 1 is…”
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Identification and cloning of human P2U purinoceptor present in osteoclastoma, bone, and osteoblasts by Bowler, W.B., Birch, M.A., Gallagher, J.A., Bilbe, G.

“…Extracellular ATP acting through purinoceptors may be an important factor in the modulation of bone turnover. In this study we cloned and sequenced the P2U…”
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P2Y2 receptors are expressed by human osteoclasts of giant cell tumor but do not mediate ATP-induced bone resorption by Bowler, W.B., Littlewood-Evans, A., Bilbe, G., Gallagher, J.A., Dixon, C.J.

“…Extracellular nucleotides acting through P2 receptors elicit a range of responses in many cell types. Previously, we have cloned the G-protein coupled P2Y2…”
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P2Y receptor subtypes differentially couple to inwardly-rectifying potassium channels by Mosbacher, J, Maier, R, Fakler, B, Glatz, A, Crespo, J, Bilbe, G

“…Subtypes of P2Y receptors are well characterized with respect to their agonist profile but little is known about differences in their intracellular signalling…”
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At Issue: A Model for Academic/Industry Collaboration by Carpenter, William T., Koenig, James I., Bilbe, Graeme, Bischoff, Serge

“…Relationships between academia and industry are increasingly intimate and commercial. While opportunities are created for each partner, there are also…”
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Mouse models of α-synucleinopathy and Lewy pathology by Sommer, B, Barbieri, S, Hofele, K, Wiederhold, K.-H, Probst, A, Mistl, C, Danner, S, Kauffmann, S, Spooren, W, Tolnay, M, Bilbe, G, van der Putten, H, Kafmann, S, Caromi, P, Ruegg, M.A

“…The discovery of two missense mutations (A53T and A30P) in the gene encoding the presynaptic protein α-synuclein (αSN) that are genetically linked to rare…”
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Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms by van Hille, B, Richener, H, Schmid, P, Puettner, I, Green, J R, Bilbe, G

“…The catalytic domain of the vacuolar proton ATPase is composed of a hexamer of three A subunits and three B subunits. Here we describe the cloning and…”
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Identification of two subunit A isoforms of the vacuolar H(+)-ATPase in human osteoclastoma by VAN HILLE, B, RICHENER, H, EVANS, D. B, GREEN, J. R, BILBE, G

“…Subunit A is thought to be the main component of the catalytic site of the vacuolar-type H(+)-ATPase. Screening of a cDNA library made from human osteoclastoma…”
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Parathyroid hormone responses of cyclic AMP-, serum- and phorbol ester-responsive reporter genes in osteoblast-like UMR-106 cells by Flühmann, B, Zimmermann, U, Muff, R, Bilbe, G, Fischer, J.A, Born, W

“…Parathyroid hormone (PTH) and PTH-related protein interact with a G protein-coupled receptor linked to the activation of adenylyl cyclase and phospholipase C…”
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PCR detection of cytokines in normal human and pagetic osteoblast‐like cells by Birch, M.A., Ginty, A.F., Walsh, C.A., Fraser, W.D., Gallagher, J.A., Bilbe, G.

“…We investigated the expression of cytokine transcripts in osteoblast‐like cells derived from explants of pagetic and normal bone. A reverse…”
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MAP kinase signaling cascades and gene expression in osteoblasts by Hipskind, R A, Bilbe, G

“…Environmental cues direct osteoblasts to proliferate and differentiate. The mitogen-activated protein (MAP) kinase pathways provide a key link between the…”
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Restin: a novel intermediate filament‐associated protein highly expressed in the Reed‐Sternberg cells of Hodgkin's disease by Bilbe, G., Delabie, J., Brüggen, J., Richener, H., Asselbergs, F.A., Cerletti, N., Sorg, C., Odink, K., Tarcsay, L., Wiesendanger, W.

“…We have identified a cDNA coding for a protein of 160 kDa which is expressed in in vitro cultured human peripheral blood monocytes. The predicted amino acid…”
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Mouse models of alpha-synucleinopathy and Lewy pathology. Alpha-synuclein expression in transgenic mice by Barbieri, S, Hofele, K, Wiederhold, K H, Probst, A, Mistl, C, Danner, S, Kauffmann, S, Sommer, B, Spooren, W, Tolnay, M, Bilbe, G, van der Putten, H

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