Search Results - "Bilal, N"

The many lives of KATs — detectors, integrators and modulators of the cellular environment by Sheikh, Bilal N., Akhtar, Asifa

“…Research over the past three decades has firmly established lysine acetyltransferases (KATs) as central players in regulating transcription. Recent advances in…”
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The non‐specific lethal (NSL) complex at the crossroads of transcriptional control and cellular homeostasis by Sheikh, Bilal N, Guhathakurta, Sukanya, Akhtar, Asifa

“…The functionality of chromatin is tightly regulated by post‐translational modifications that modulate transcriptional output from target loci. Among the…”
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The non-specific lethal (NSL) complex at the crossroads of transcriptional control and cellular homeostasis by Sheikh, Bilal N, Guhathakurta, Sukanya, Akhtar, Asifa

“…The functionality of chromatin is tightly regulated by post-translational modifications that modulate transcriptional output from target loci. Among the…”
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Crafting the Brain – Role of Histone Acetyltransferases in Neural Development and Disease by Sheikh, Bilal N

“…The human brain is a highly specialized organ containing nearly 170 billion cells with specific functions. Development of the brain requires adequate…”
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Vascular Homeostasis and Inflammation in Health and Disease-Lessons from Single Cell Technologies by Bondareva, Olga, Sheikh, Bilal N

“…The vascular system is critical infrastructure that transports oxygen and nutrients around the body, and dynamically adapts its function to an array of…”
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MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells by Sheikh, Bilal N., Yang, Yuqing, Schreuder, Jaring, Nilsson, Susan K., Bilardi, Rebecca, Carotta, Sebastian, McRae, Helen M., Metcalf, Donald, Voss, Anne K., Thomas, Tim

“…Hematopoietic stem cells (HSCs) are conventionally thought to be at the apex of a hierarchy that produces all mature cells of the blood. The quintessential…”
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The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity by AlZaim, Ibrahim, de Rooij, Laura P.M.H, Sheikh, Bilal N., Börgeson, Emma, Kalucka, Joanna

“…Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic metabolic homeostasis. Additionally, adipose tissue is a pivotal…”
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MOZ Regulates the Tbx1 Locus, and Moz Mutation Partially Phenocopies DiGeorge Syndrome by Voss, Anne K., Vanyai, Hannah K., Collin, Caitlin, Dixon, Mathew P., McLennan, Tamara J., Sheikh, Bilal N., Scambler, Peter, Thomas, Tim

“…DiGeorge syndrome, caused by a 22q11 microdeletion or mutation of the TBX1 gene, varies in severity greatly, even among monozygotic twins. Epigenetic phenomena…”
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Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth by Baell, Jonathan B., Leaver, David J., Hermans, Stefan J., Kelly, Gemma L., Brennan, Margs S., Downer, Natalie L., Nguyen, Nghi, Wichmann, Johannes, McRae, Helen M., Yang, Yuqing, Cleary, Ben, Lagiakos, H. Rachel, Mieruszynski, Stephen, Pacini, Guido, Vanyai, Hannah K., Bergamasco, Maria I., May, Rose E., Davey, Bethany K., Morgan, Kimberly J., Sealey, Andrew J., Wang, Beinan, Zamudio, Natasha, Wilcox, Stephen, Garnham, Alexandra L., Sheikh, Bilal N., Aubrey, Brandon J., Doggett, Karen, Chung, Matthew C., de Silva, Melanie, Bentley, John, Pilling, Pat, Hattarki, Meghan, Dolezal, Olan, Dennis, Matthew L., Falk, Hendrik, Ren, Bin, Charman, Susan A., White, Karen L., Rautela, Jai, Newbold, Andrea, Hawkins, Edwin D., Johnstone, Ricky W., Huntington, Nicholas D., Peat, Thomas S., Heath, Joan K., Strasser, Andreas, Parker, Michael W., Smyth, Gordon K., Street, Ian P., Monahan, Brendon J., Voss, Anne K., Thomas, Tim

“…Acetylation of histones by lysine acetyltransferases (KATs) is essential for chromatin organization and function 1 . Among the genes coding for the MYST family…”
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Evolutionary conserved NSL complex/BRD4 axis controls transcription activation via histone acetylation by Gaub, Aline, Sheikh, Bilal N., Basilicata, M. Felicia, Vincent, Marie, Nizon, Mathilde, Colson, Cindy, Bird, Matthew J., Bradner, James E., Thevenon, Julien, Boutros, Michael, Akhtar, Asifa

“…Cells rely on a diverse repertoire of genes for maintaining homeostasis, but the transcriptional networks underlying their expression remain poorly understood…”
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First insights into molecular basis identification of 16 s ribosomal RNA gene of Staphylococcus aureus isolated from Sudan by Gumaa, Manal A, Idris, Abeer Babiker, Bilal, N. E, Hassan, Mohamed A

“…Abstract Objective In this study, we analyzed the molecular evolution of Staphylococcus aureus isolates using 16S rRNA gene and phylogenetic analysis to detect…”
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Ankara'nın başkent oluşu by Şimşir, Bilal N

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On experiments in harmonically excited cantilever plates with 1:2 internal resonance by Bilal, N., Tripathi, A., Bajaj, A. K.

“…This work presents some experimental results for resonant nonlinear response of hyperelastic plates for 1:2 internal resonance. Previously developed topology…”
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Cultured brain pericytes adopt an immature phenotype and require endothelial cells for expression of canonical markers and ECM genes by Oliveira, Fabiana, Bondareva, Olga, Rodríguez-Aguilera, Jesús Rafael, Sheikh, Bilal N

“…Pericytes (PCs) are essential components of the blood brain barrier. Brain PCs are critical for dynamically regulating blood flow, for maintaining vascular…”
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MOZ and BMI1 act synergistically to maintain hematopoietic stem cells by Sheikh, Bilal N, Metcalf, Donald, Voss, Anne K, Thomas, Tim

“…Chromatin plays a central role in maintaining hematopoietic stem cells and during their stepwise differentiation. Although a large number of histone…”
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Ultra-Low Energy CNFET-Based Ternary Combinational Circuits Designs by Jaber, Ramzi A., Aljaam, Jihad Mohamed, Owaydat, Bilal N., Al-Maadeed, Somaya Ali, Kassem, Abdallah, Haidar, Ali Massoud

“…The embedded systems, IoT (Internet of Things) devices, and portable electronic devices spread very quickly recently. Most of them depend on batteries to…”
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Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs by Kokot, Karoline E., Kneuer, Jasmin M., John, David, Rebs, Sabine, Möbius-Winkler, Maximilian N., Erbe, Stephan, Müller, Marion, Andritschke, Michael, Gaul, Susanne, Sheikh, Bilal N., Haas, Jan, Thiele, Holger, Müller, Oliver J., Hille, Susanne, Leuschner, Florian, Dimmeler, Stefanie, Streckfuss-Bömeke, Katrin, Meder, Benjamin, Laufs, Ulrich, Boeckel, Jes-Niels

“…Alterations of RNA editing that affect the secondary structure of RNAs can cause human diseases. We therefore studied RNA editing in failing human hearts…”
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Subtle Changes in the Levels of BCL-2 Proteins Cause Severe Craniofacial Abnormalities by Grabow, Stephanie, Kueh, Andrew J., Ke, Francine, Vanyai, Hannah K., Sheikh, Bilal N., Dengler, Michael A., Chiang, William, Eccles, Samantha, Smyth, Ian M., Jones, Lynelle K., de Sauvage, Frederic J., Scott, Mark, Whitehead, Lachlan, Voss, Anne K., Strasser, Andreas

“…Apoptotic cell death removes unwanted cells and is regulated by interactions between pro-survival and pro-apoptotic members of the BCL-2 protein family. The…”
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Novel Long Noncoding RNA HEAT4 Affects Monocyte Subtypes, Reducing Inflammation and Promoting Vascular Healing by Kneuer, Jasmin M, Grajek, Ignacy A, Winkler, Melanie, Erbe, Stephan, Meinecke, Tim, Weiss, Ronald, Garfias-Veitl, Tania, Sheikh, Bilal N, König, Ann-Christine, Möbius-Winkler, Maximilian N, Kogel, Alexander, Kresoja, Karl-Patrik, Rosch, Sebastian, Kokot, Karoline E, Filipova, Vanina, Gaul, Susanne, Thiele, Holger, Lurz, Philipp, von Haehling, Stephan, Speer, Thimoteus, Laufs, Ulrich, Boeckel, Jes-Niels

“…Activation of the immune system contributes to cardiovascular diseases. The role of human-specific long noncoding RNAs in cardioimmunology is poorly…”
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Loss of PHF6 causes spontaneous seizures, enlarged brain ventricles and altered transcription in the cortex of a mouse model of the Börjeson-Forssman-Lehmann intellectual disability syndrome by McRae, Helen M, Leong, Melody P Y, Bergamasco, Maria I, Garnham, Alexandra L, Hu, Yifang, Corbett, Mark A, Whitehead, Lachlan, El-Saafin, Farrah, Sheikh, Bilal N, Wilcox, Stephen, Hannan, Anthony J, Gécz, Jozef, Smyth, Gordon K, Thomas, Tim, Voss, Anne K

“…Börjeson-Forssman-Lehmann syndrome (BFLS) is an X-linked intellectual disability and endocrine disorder caused by pathogenic variants of plant homeodomain…”
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