Search Results - "Bikram, Malavosklish"

Gold-silver alloy nanoshells: a new candidate for nanotherapeutics and diagnostics by Gheorghe, Dana E, Cui, Lili, Karmonik, Christof, Brazdeikis, Audrius, Penaloza, Jose M, Young, Joseph K, Drezek, Rebekah A, Bikram, Malavosklish

“…We have developed novel gold-silver alloy nanoshells as magnetic resonance imaging (MRI) dual T 1 (positive) and T 2 (negative) contrast agents as an…”
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Combination of local, nonviral IL12 gene therapy and systemic paclitaxel treatment in a metastatic breast cancer model by Janát-Amsbury, Margit Maria, Yockman, James W, Lee, Minhyung, Kern, Steven, Furgeson, Darin Y, Bikram, Malavosklish, Kim, Sung Wan

“…Repeated, local, nonviral IL12 (interleukin-12) gene delivery decreased tumor progression and increased immunogenicity. We combined our IL12 gene delivery with…”
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Endochondral bone formation from hydrogel carriers loaded with BMP2-transduced cells by Bikram, Malavosklish, Fouletier-Dilling, Christine, Hipp, John A, Gannon, Francis, Davis, Alan R, Olmsted-Davis, Elizabeth A, West, Jennifer L

“…The success of ex vivo viral gene therapy systems for promoting bone formation could be improved through the development of systems to spatially localize gene…”
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Sp1-dependent regulation of the RTP801 promoter and its application to hypoxia-inducible VEGF plasmid for ischemic disease by Lee, Minhyung, Bikram, Malavosklish, Oh, Seungjoon, Bull, David A, Kim, Sung Wan

“…Gene therapy using vascular endothelial growth factor (VEGF) is a new potential treatment of ischemic disease. To be safe and effective, VEGF expression should…”
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Biodegradable Poly(ethylene glycol)-co-poly(l-lysine)-g-histidine Multiblock Copolymers for Nonviral Gene Delivery by BIKRAM, Malavosklish, AHN, Cheol-Hee, CHAE, Su Young, LEE, Minhyung, YOCKMAN, James W., KIM, Sung Wan

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Thermo-responsive systems for controlled drug delivery by Bikram, Malavosklish, West, Jennifer L

“…Controlled drug delivery systems represent advanced systems that can be tightly modulated by stimuli in order to treat diseases in which sustained drug release…”
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Temperature-sensitive hydrogels with SiO2-Au nanoshells for controlled drug delivery by BIKRAM, Malavosklish, GOBIN, Andre M, WHITMIRE, Rachel E, WEST, Jennifer L

“…Silica-gold (SiO(2)-Au) nanoshells are a new class of nanoparticles that consist of a silica dielectric core that is surrounded by a gold shell. These…”
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Novel nanomedicine-based MRI contrast agents for gynecological malignancies by Mody, Vicky V., Nounou, Mohamed Ismail, Bikram, Malavosklish

“…Gynecological cancers result in significant morbidity and mortality in women despite advances in treatment and diagnosis. This is due to detection of the…”
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Novel reducible linear L-lysine-modified copolymers as efficient nonviral vectors by Nounou, Mohamed Ismail, Emmanouil, Kalyopy, Chung, Samuel, Pham, Thu, Lu, Zhuoyuan, Bikram, Malavosklish

“…The development of biodegradable gene delivery systems with high transfection efficiencies is paramount to the clinical translation of nonviral gene carriers…”
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Biodegradable poly(ethylene glycol)-co-poly(L-lysine)-g-histidine multiblock copolymers for nonviral gene delivery by BIKRAM, Malavosklish, AHN, Cheol-Hee, SU YOUNG CHAE, LEE, Minhyung, YOCKMAN, James W, SUNG WAN KIM

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Interactions of Liposome Carriers with Infectious Fungal Hyphae Reveals the Role of β‑Glucans by Chavan, Neelam L, Young, Joseph K, Drezek, Rebekah A, Lewis, Russell, Bikram, Malavosklish

“…Relatively little is known about how liposomal formulations modulate drug delivery to fungal pathogens. We compared patterns of hyphal cell wall binding for…”
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Novel nanomedicine-based MRI contrast agents for gynecological malignancies: The Role of Gene- and Drug Delivery in Women's Health - Unmet Clinical Needs and Future Opportunities by MODY, Vicky V, MOHAMED ISMAIL NOUNOU, BIKRAM, Malavosklish

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Development of Non-Viral Gene Delivery Carriers for Ischemic Heart Disease (IHD) by Bikram, Malavosklish, Nounou, Mohamed Ismail, Li, Dongling, Silva, Guilherme V., McConnell, Bradley K.

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Fast in vivo quantification of T1 and T2 MRI relaxation times in the myocardium based on inversion recovery SSFP with in vitro validation post Gd-based contrast administration by Karmonik, Christof, Malaty, Adam, Bikram, Malavosklish, Schmitt, Peter, Partovi, Sasan, Shah, Dipan J.

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Temperature-sensitive hydrogels with SiO sub(2)-Au nanoshells for controlled drug delivery by Bikram, Malavosklish, Gobin, Andre M, Whitmire, Rachel E, West, Jennifer L

“…Silica-gold (SiO sub(2)-Au) nanoshells are a new class of nanoparticles that consist of a silica dielectric core that is surrounded by a gold shell. These…”
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Long-circulating DNA-complexed biodegradable multiblock copolymers for gene delivery: degradation profiles and evidence of dysopsonization by Bikram, Malavosklish, Lee, Minhyung, Chang, Chien-Wen, Janát-Amsbury, Margit-María, Kern, Steven E., Kim, Sung Wan

“…Biodegradable cationic polymers have become promising alternatives to traditional polycationic gene delivery systems in which the high charge densities of high…”
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Temperature-sensitive hydrogels with SiO 2–Au nanoshells for controlled drug delivery by Bikram, Malavosklish, Gobin, Andre M., Whitmire, Rachel E., West, Jennifer L.

“…Silica–gold (SiO 2–Au) nanoshells are a new class of nanoparticles that consist of a silica dielectric core that is surrounded by a gold shell. These…”
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681. Hydrogel Encapsulation of Adenovirus-Transduced Cells Expressing BMP2 for Local Osteoinduction by Bikram, Malavosklish, Fouletier-dilling, Christine, Gobin, Andre M, Davis, Alan R, Olmsted-davis, Elizabeth A, West, Jennifer L

“…The use of gene therapy as an alternative to autogenous bone grafting techniques commonly utilized to promote regeneration and healing have been very promising…”
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Local, non-viral IL-12 gene therapy using a water soluble lipopolymer as carrier system combined with systemic paclitaxel for cancer treatment by Janát-Amsbury, Margit Maria, Yockman, James W., Lee, Minhyung, Kern, Steven, Furgeson, Darin Y., Bikram, Malavosklish, Kim, Sung Wan

“…Development of improved gene transfer methods is needed for gene therapy to achieve its clinical potential. The use of biocompatible polymeric gene carriers…”
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Biodegradable multiblock copolymers for gene delivery by Bikram, Malavosklish

“…Nonviral gene delivery has developed into a promising alternative to viral gene delivery and has the potential to correct many genetic disorders as well as to…”
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