Search Results - "Bikos, V"

High-quality full-length immunoglobulin profiling with unique molecular barcoding by Turchaninova, M A, Davydov, A, Britanova, O V, Shugay, M, Bikos, V, Egorov, E S, Kirgizova, V I, Merzlyak, E M, Staroverov, D B, Bolotin, D A, Mamedov, I Z, Izraelson, M, Logacheva, M D, Kladova, O, Plevova, K, Pospisilova, S, Chudakov, D M

“…This protocol enables high-throughput sequencing analysis of the full-length immunoglobulin repertoires in human and mouse using unique molecular identifiers…”
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Restrictions in the T-cell repertoire of chronic lymphocytic leukemia: high-throughput immunoprofiling supports selection by shared antigenic elements by Vardi, A, Vlachonikola, E, Karypidou, M, Stalika, E, Bikos, V, Gemenetzi, K, Maramis, C, Siorenta, A, Anagnostopoulos, A, Pospisilova, S, Maglaveras, N, Chouvarda, I, Stamatopoulos, K, Hadzidimitriou, A

“…Immunoglobulin (IG) gene repertoire restrictions strongly support antigen selection in the pathogenesis of chronic lymphocytic leukemia (CLL). Given the…”
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Multiple productive IGH rearrangements denote oligoclonality even in immunophenotypically monoclonal CLL by Brazdilova, K, Plevova, K, Skuhrova Francova, H, Kockova, H, Borsky, M, Bikos, V, Malcikova, J, Oltova, A, Kotaskova, J, Tichy, B, Brychtova, Y, Mayer, J, Doubek, M, Pospisilova, S

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Over 30% of patients with splenic marginal zone lymphoma express the same immunoglobulin heavy variable gene: ontogenetic implications by Bikos, V, Darzentas, N, Hadzidimitriou, A, Davis, Z, Hockley, S, Traverse-Glehen, A, Algara, P, Santoro, A, Gonzalez, D, Mollejo, M, Dagklis, A, Gangemi, F, Bosler, D S, Bourikas, G, Anagnostopoulos, A, Tsaftaris, A, Iannitto, E, Ponzoni, M, Felman, P, Berger, F, Belessi, C, Ghia, P, Papadaki, T, Dogan, A, Degano, M, Matutes, E, Piris, M A, Oscier, D, Stamatopoulos, K

“…We performed an immunogenetic analysis of 345 IGHV–IGHD–IGHJ rearrangements from 337 cases with primary splenic small B-cell lymphomas of marginal-zone origin…”
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Molecular evidence for EBV and CMV persistence in a subset of patients with chronic lymphocytic leukemia expressing stereotyped IGHV4-34 B-cell receptors by Kostareli, E, Hadzidimitriou, A, Stavroyianni, N, Darzentas, N, Athanasiadou, A, Gounari, M, Bikos, V, Agathagelidis, A, Touloumenidou, T, Zorbas, I, Kouvatsi, A, Laoutaris, N, Fassas, A, Anagnostopoulos, A, Belessi, C, Stamatopoulos, K

“…The chronic lymphocytic leukemia (CLL) immunoglobulin repertoire is uniquely characterized by the presence of stereotyped B-cell receptors (BCRs). A major BCR…”
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Selection of antigen receptors in splenic marginal-zone lymphoma: further support from the analysis of the immunoglobulin light-chain gene repertoire by Bikos, V, Stalika, E, Baliakas, P, Darzentas, N, Davis, Z, Traverse-Glehen, A, Dagklis, A, Kanellis, G, Anagnostopoulos, A, Tsaftaris, A, Ponzoni, M, Berger, F, Felman, P, Ghia, P, Papadaki, T, Oscier, D, Belessi, C, Stamatopoulos, K

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ARResT/AssignSubsets: a novel application for robust subclassification of chronic lymphocytic leukemia based on B cell receptor IG stereotypy by Bystry, Vojtech, Agathangelidis, Andreas, Bikos, Vasilis, Sutton, Lesley Ann, Baliakas, Panagiotis, Hadzidimitriou, Anastasia, Stamatopoulos, Kostas, Darzentas, Nikos

“…An ever-increasing body of evidence supports the importance of B cell receptor immunoglobulin (BcR IG) sequence restriction, alias stereotypy, in chronic…”
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CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase by Hernández-Sánchez, María, Kotaskova, Jana, Rodríguez, Ana E, Radova, Lenka, Tamborero, David, Abáigar, María, Plevova, Karla, Benito, Rocío, Tom, Nikola, Quijada-Álamo, Miguel, Bikos, Vasileos, Martín, Ana África, Pal, Karol, García de Coca, Alfonso, Doubek, Michael, López-Bigas, Nuria, Hernández-Rivas, Jesús-María, Pospisilova, Sarka

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Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia by Polychronidou, Eleftheria, Kalamaras, Ilias, Agathangelidis, Andreas, Sutton, Lesley-Ann, Yan, Xiao-Jie, Bikos, Vasilis, Vardi, Anna, Mochament, Konstantinos, Chiorazzi, Nicholas, Belessi, Chrysoula, Rosenquist, Richard, Ghia, Paolo, Stamatopoulos, Kostas, Vlamos, Panayiotis, Chailyan, Anna, Overby, Nanna, Marcatili, Paolo, Hatzidimitriou, Anastasia, Tzovaras, Dimitrios

“…Although the etiology of chronic lymphocytic leukemia (CLL), the most common type of adult leukemia, is still unclear, strong evidence implicates antigen…”
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An Immunogenetic Signature of Ongoing Antigen Interactions in Splenic Marginal Zone Lymphoma Expressing IGHV1-204 Receptors by Bikos, Vasilis, Karypidou, Maria, Stalika, Evangelia, Baliakas, Panagiotis, Xochelli, Aliki, Sutton, Lesley-Ann, Papadopoulos, George, Agathangelidis, Andreas, Papadopoulou, Evdoxia, Davis, Zadie, Algara, Patricia, Kanellis, George, Traverse-Glehen, Alexandra, Mollejo, Manuela, Anagnostopoulos, Achilles, Ponzoni, Maurilio, Gonzalez, David, Pospisilova, Sarka, Matutes, Estella, Piris, Miguel Angel, Papadaki, Theodora, Ghia, Paolo, Rosenquist, Richard, Oscier, David, Darzentas, Nikos, Tzovaras, Dimitrios, Belessi, Chrysoula, Hadzidimitriou, Anastasia, Stamatopoulos, Kostas

“…Prompted by the extensive biases in the immunoglobulin (IG) gene repertoire of splenic marginal-zone lymphoma (SMZL), supporting antigen selection in SMZL…”
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HIGH-THROUGHPUT T-CELL RECEPTOR GENE REPERTOIRE PROFILING IN CHRONIC LYMPHOCYTIC LEUKEMIA SUBSET #4: FURTHER EVIDENCE OF ANTIGENIC STIMULATION by Vardi, A., Stalika, E., Gkoufas, A., Karipidou, M., Maramis, C., Bikos, V., Pospisilova, S., Anagnostopoulos, A., Maglaveras, N., Chouvarda, I., Stamatopoulos, Kostas, Hadzidimitriou, A.

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Splenic marginal-zone lymphoma: ontogeny and genetics by Baliakas, Panagiotis, Strefford, Jonathan C., Bikos, Vasilis, Parry, Marina, Stamatopoulos, Kostas, Oscier, David

“…Abstract Splenic marginal-zone lymphoma (SMZL) is a rare tumor that has recently emerged as a prototype for how the interplay between genetics and environment…”
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Matched Pattern Discovery Across Paired Immunoglobulin Heavy and Light Chains in CLL Reveals Unique Subset-Defining Amino Acid Associations by Sutton, L. A., Moschonas, P., Vardi, A., Bikos, V., Yan, X. J., Chatzouli, M., Anagnostopoulos, A., Belessi, C., Chiorazzi, N., Rosenquist, Richard Brandell, Tzovaras, D., Stamatopoulos, Kostas, Hadzidimitriou, A.

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HIGHER-ORDER IMMUNOGLOBULIN SEQUENCE RELATIONS FOR MAJOR SUBSETS OF CHRONIC LYMPHOCYTIC LEUKEMIA: UNIQUENESS VERSUS EQUIVALENCE by Agathangelidis, A., Bystry, V., Hadzidimitriou, A., Sutton, L. A., Minga, E., Kienle, D., Davis, Z., Yan, X. J., Shanafelt, T., Boudjogra, M., Plevova, K., Gounari, M., Xochelli, A., Navarro, A., Chatzouli, M., Pedersen, L. B., Baliakas, Panagiotis, Scarfo, L., Rossi, D., Veronese, S., Facco, M., Bikos, V., Karan-Djurasevic, T., Pavlovic, S., Mansouri, Larry, Poiron, C., Chu, C. C., Stalika, E., Giudicelli, V., Panagiotidis, P., Sudarikov, A., Anagnostopoulos, A., Trentin, L., Catherwood, M., Montillo, M., Gaidano, G., Campo, E., Geisler, C. H., Langerak, A. W., Pospisilova, S., Lefranc, M. P., Chiorazzi, N., Oscier, D., Jelinek, D. F., Stilgenbauer, S., Belessi, C., Davi, F., Rosenquist, Richard, Ghia, P., Darzentas, N., Stamatopoulos, Kostas

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