Search Results - "Bikker, Floris J"
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Letter to the editor concerning Valstar et al., [Radiother Oncol 2020 Sep 23;S0167-8140(20)30809-4. doi: 10.1016/j.radonc.2020.09.034]
Published in Radiotherapy and oncology (01-01-2021)Get full text
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Current and Potential Applications of Monoterpenes and Their Derivatives in Oral Health Care
Published in Molecules (Basel, Switzerland) (01-10-2023)“…Plant products have been employed in medicine for centuries. As the world becomes more health-conscious, there is a growing interest in natural and minimally…”
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Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes
Published in Proceedings of the National Academy of Sciences - PNAS (03-11-2020)“…Priming of CD8⁺ T cells by dendritic cells (DCs) is crucial for the generation of effective antitumor immune responses. Here, we describe a liposomal vaccine…”
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The Bigger Picture: Why Oral Mucosa Heals Better Than Skin
Published in Biomolecules (Basel, Switzerland) (06-08-2021)“…Wound healing is an essential process to restore tissue integrity after trauma. Large skin wounds such as burns often heal with hypertrophic scarring and…”
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Carbon quantum dots as immune modulatory therapy in a Sjögren's syndrome mouse model
Published in Oral diseases (01-04-2024)“…Objectives The objective of the study was to evaluate the therapeutic effects of carbon quantum dots (CQDs) in immunomodulation on non‐obese diabetic (NOD)…”
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Sialagogic Effects Through Olfactory Stimulation with Mastic Resin and α-pinene Volatiles in vivo
Published in Biomedicine & pharmacotherapy (01-12-2023)“…Xerostomia, often associated with decreased saliva quality, poses challenges due to limited treatment efficacy. This study aimed to investigate alternative…”
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Nepenthesin protease activity indicates digestive fluid dynamics in carnivorous nepenthes plants
Published in PloS one (09-03-2015)“…Carnivorous plants use different morphological features to attract, trap and digest prey, mainly insects. Plants from the genus Nepenthes possess specialized…”
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Mechanisms of Porphyromonas gingivalis to translocate over the oral mucosa and other tissue barriers
Published in Journal of oral microbiology (31-12-2023)“…The oral pathogen Porphyromonas gingivalis is not only associated with periodontitis but also with systemic diseases elsewhere in the body. The mechanisms by…”
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Parvimonas micra stimulates expression of gingipains from Porphyromonas gingivalis in multi-species communities
Published in Anaerobe (01-02-2019)“…Dental biofilms are complex ecosystems containing many bacterial species that live in mutualistic relationships. These interactions can profoundly affect the…”
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Colorimetric Assay for the Detection of Typical Biomarkers for Periodontitis Using a Magnetic Nanoparticle Biosensor
Published in Analytical chemistry (Washington) (15-12-2015)“…Periodontitis is a chronic disease which affects at least 10% of the population. If untreated, periodontitis can lead to teeth loss. Unfortunately, current…”
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Antimicrobial and immunomodulatory activities of PR-39 derived peptides
Published in PloS one (01-04-2014)“…The porcine cathelicidin PR-39 is a host defence peptide that plays a pivotal role in the innate immune defence of the pig against infections. Besides direct…”
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Scent of relief: Mastic resin scent recovers salivation in chronic dry mouth patients
Published in Biomedicine & pharmacotherapy (01-09-2024)“…Olfactory stimulation with mastic resin, derived from the Pistacia lentiscus tree, demonstrated a bona fide sialagogic effect in healthy volunteers [1]. Its…”
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A review on the role of salivary MUC5B in oral health
Published in Journal of oral biosciences (01-12-2022)“…The salivary glycoprotein MUC5B plays a versatile role in maintaining oral health. It contributes to lubrication, pellicle formation, antimicrobial defense,…”
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Immunomodulatory and Anti-Inflammatory Activities of Chicken Cathelicidin-2 Derived Peptides
Published in PloS one (05-02-2016)“…Host Defence Peptides and derived peptides are promising classes of antimicrobial and immunomodulatory lead compounds. For this purpose we examined whether…”
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Probiotics Support Resilience of the Oral Microbiota during Resolution after Experimental Gingivitis—A Randomized, Double-Blinded, Placebo-Controlled Trial
Published in Nutrients (01-11-2023)“…The present study aims to test whether probiotics protect against experimental gingivitis incited by 14 days of oral hygiene neglect and/or subsequently…”
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Probiotics Partly Suppress the Impact of Sugar Stress on the Oral Microbiota—A Randomized, Double-Blinded, Placebo-Controlled Trial
Published in Nutrients (01-11-2023)“…The aim was to test if probiotics counteract oral dysbiosis during 14 days of sugar stress and subsequently help restore oral homeostasis. Eighty healthy…”
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A rapid, non-invasive tool for periodontitis screening in a medical care setting
Published in BMC oral health (23-05-2019)“…Since periodontitis is bi-directionally associated with several systemic diseases, such as diabetes mellitus and cardiovascular diseases, it is important for…”
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Comparing SARS-CoV-2 Viral Load in Human Saliva to Oropharyngeal Swabs, Nasopharyngeal Swabs, and Sputum: A Systematic Review and Meta-Analysis
Published in The Canadian journal of infectious diseases & medical microbiology (10-08-2023)“…A systematic review and meta-analysis were conducted to investigate the SARS-CoV-2 viral load in human saliva and compared it with the loads in oropharyngeal…”
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Supragingival microbiota, cytokines, and proteins in individuals with different trajectories in experimental gingivitis
Published in Journal of oral microbiology (31-12-2024)“…Gingivitis in response to biofilm formation may exhibit different trajectories. The purposes of the present study were to characterize the composition of the…”
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Effects of Escherichia coli LPS Structure on Antibacterial and Anti-Endotoxin Activities of Host Defense Peptides
Published in Pharmaceuticals (Basel, Switzerland) (18-10-2023)“…The binding of Host Defense Peptides (HDPs) to the endotoxin of Gram-negative bacteria has important unsolved aspects. For most HDPs, it is unclear if binding…”
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