Search Results - "Biilmann Rønn, Lars Christian"

Identification of the first small-molecule ligand of the neuronal receptor sortilin and structure determination of the receptor-ligand complex by Andersen, Jacob Lauwring, Schrøder, Tenna Juul, Christensen, Søren, Strandbygård, Dorthe, Pallesen, Lone Tjener, García-Alai, Maria Marta, Lindberg, Samsa, Langgård, Morten, Eskildsen, Jørgen Calí, David, Laurent, Tagmose, Lena, Simonsen, Klaus Baek, Maltas, Philip James, Rønn, Lars Christian Biilmann, de Jong, Inge E. M., Malik, Ibrahim John, Egebjerg, Jan, Karlsson, Jens-Jacob, Uppalanchi, Srinivas, Sakumudi, Durga Rao, Eradi, Pradheep, Watson, Steven P., Thirup, Søren

“…Sortilin is a type I membrane glycoprotein belonging to the vacuolar protein sorting 10 protein (Vps10p) family of sorting receptors and is most abundantly…”
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Does neuroglobin protect neurons from ischemic insult? A quantitative investigation of neuroglobin expression following transient MCAo in spontaneously hypertensive rats by Hundahl, Christian, Kelsen, Jesper, Kjær, Katrine, Rønn, Lars Christian Biilmann, Weber, Roy Edwin, Geuens, Eva, Hay-Schmidt, Anders, Nyengaard, Jens Randel

“…Neuroglobin (NGB) is a recently characterized heme globin expressed primarily in retinal nerve cells and at very low levels in endocrine-active regions of…”
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Chloride channel blockers inhibit iNOS expression and NO production in IFNγ-stimulated microglial BV2 cells by Kjær, Katrine, Strøbæk, Dorte, Christophersen, Palle, Rønn, Lars Christian Biilmann

“…Abstract Microglial cells play an important role during neuroinflammation in the central nervous system. Among other factors, activated microglia produce…”
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The identification of novel acid isostere based inhibitors of the VPS10P family sorting receptor Sortilin by Andersen, Jacob Lauwring, Lindberg, Samsa, Langgård, Morten, Maltas, Philip J., Rønn, Lars Christian Biilmann, Bundgaard, Christoffer, Strandbygaard, Dorthe, Thirup, Søren, Watson, Stephen P

“…Using fragment based and structure based drug discovery strategies, a series of novel Sortilin inhibitors has been identified. The inhibitors are based on the…”
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The identification of AF38469: an orally bioavailable inhibitor of the VPS10P family sorting receptor Sortilin by Schrøder, Tenna Juul, Christensen, Søren, Lindberg, Samsa, Langgård, Morten, David, Laurent, Maltas, Philip J, Eskildsen, Jørgen, Jacobsen, Jan, Tagmose, Lena, Simonsen, Klaus Bæk, Biilmann Rønn, Lars Christian, de Jong, Inge E M, Malik, Ibrahim J, Karlsson, Jens-Jakob, Bundgaard, Christoffer, Egebjerg, Jan, Stavenhagen, Jeffrey B, Strandbygård, Dorthe, Thirup, Søren, Andersen, Jacob Lauwring, Uppalanchi, Srinivas, Pervaram, Sridhar, Kasturi, Shiva Prasad, Eradi, Pradheep, Sakumudi, Durga Rao, Watson, Stephen P

“…The identification of the novel, selective, orally bioavailable Sortilin inhibitor AF38469 is described. Structure-activity relationships and syntheses are…”
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Inhibition of the potassium channel KCa3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury by Staal, Roland G.W., Khayrullina, Tanzilya, Zhang, Hong, Davis, Scott, Fallon, Shaun M., Cajina, Manuel, Nattini, Megan E., Hu, Andrew, Zhou, Hua, Poda, Suresh Babu, Zorn, Stevin, Chandrasena, Gamini, Dale, Elena, Cambpell, Brian, Biilmann Rønn, Lars Christian, Munro, Gordon, Mӧller, Thomas

“…Neuropathic pain is a debilitating, chronic condition with a significant unmet need for effective treatment options. Recent studies have demonstrated that in…”
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Inhibition of the potassium channel K Ca 3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury by Staal, Roland G W, Khayrullina, Tanzilya, Zhang, Hong, Davis, Scott, Fallon, Shaun M, Cajina, Manuel, Nattini, Megan E, Hu, Andrew, Zhou, Hua, Poda, Suresh Babu, Zorn, Stevin, Chandrasena, Gamini, Dale, Elena, Cambpell, Brian, Biilmann Rønn, Lars Christian, Munro, Gordon, Mӧller, Thomas

“…Neuropathic pain is a debilitating, chronic condition with a significant unmet need for effective treatment options. Recent studies have demonstrated that in…”
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Erratum to “Chloride channel blockers inhibit iNOS expression and NO production in IFNγ-stimulated microglial BV2 cells” [Brain Res. 128 (2009) 15–24] by Kjær, Katrine, Strøbæk, Dorte, Christophersen, Palle, Biilmann Rønn, Lars Christian

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Chloride channel blockers inhibit iNOS expression and NO production in IFNgamma-stimulated microglial BV2 cells by Kjaer, Katrine, Strøbaek, Dorte, Christophersen, Palle, Rønn, Lars Christian Biilmann

“…Microglial cells play an important role during neuroinflammation in the central nervous system. Among other factors, activated microglia produce nitric oxide…”
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