Search Results - "Bignon, Eduardo A"

Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation by Willensky, Shmuel, Bar-Rogovsky, Hagit, Bignon, Eduardo A, Tischler, Nicole D, Modis, Yorgo, Dessau, Moshe

“…Hantaviruses are important emerging human pathogens and are the causative agents of serious diseases in humans with high mortality rates. Like other members in…”
Get full text

Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc by Guardado-Calvo, Pablo, Bignon, Eduardo A, Stettner, Eva, Jeffers, Scott Allen, Pérez-Vargas, Jimena, Pehau-Arnaudet, Gerard, Tortorici, M Alejandra, Jestin, Jean-Luc, England, Patrick, Tischler, Nicole D, Rey, Félix A

“…Hantaviruses are zoonotic viruses transmitted to humans by persistently infected rodents, giving rise to serious outbreaks of hemorrhagic fever with renal…”
Get full text

The structure of a prokaryotic viral envelope protein expands the landscape of membrane fusion proteins by El Omari, Kamel, Li, Sai, Kotecha, Abhay, Walter, Thomas S., Bignon, Eduardo A., Harlos, Karl, Somerharju, Pentti, De Haas, Felix, Clare, Daniel K., Molin, Mika, Hurtado, Felipe, Li, Mengqiu, Grimes, Jonathan M., Bamford, Dennis H., Tischler, Nicole D., Huiskonen, Juha T., Stuart, David I., Roine, Elina

“…Lipid membrane fusion is an essential function in many biological processes. Detailed mechanisms of membrane fusion and the protein structures involved have…”
Get full text

Molecular organization and dynamics of the fusion protein Gc at the hantavirus surface by Bignon, Eduardo A, Albornoz, Amelina, Guardado-Calvo, Pablo, Rey, Félix A, Tischler, Nicole D

“…The hantavirus envelope glycoproteins Gn and Gc mediate virion assembly and cell entry, with Gc driving fusion of viral and endosomal membranes. Although the…”
Get full text

Halorubrum pleomorphic virus-6 Membrane Fusion Is Triggered by an S-Layer Component of Its Haloarchaeal Host by Bignon, Eduardo A, Chou, Kevin R, Roine, Elina, Tischler, Nicole D

“…(1) Background: Haloarchaea comprise extremely halophilic organisms of the Archaea domain. They are single-cell organisms with distinctive membrane lipids and…”
Get full text

Inhibition of the Hantavirus Fusion Process by Predicted Domain III and Stem Peptides from Glycoprotein Gc by Barriga, Gonzalo P, Villalón-Letelier, Fernando, Márquez, Chantal L, Bignon, Eduardo A, Acuña, Rodrigo, Ross, Breyan H, Monasterio, Octavio, Mardones, Gonzalo A, Vidal, Simon E, Tischler, Nicole D

“…Hantaviruses can cause hantavirus pulmonary syndrome or hemorrhagic fever with renal syndrome in humans. To enter cells, hantaviruses fuse their envelope…”
Get full text

Pleomorphic viruses establish stable relationship with marine hyperthermophilic archaea by Baquero, Diana P, Bignon, Eduardo A, Krupovic, Mart

“…Non-lytic viruses with enveloped pleomorphic virions (family Pleolipoviridae) are ubiquitous in hypersaline environments across the globe and are associated…”
Get full text

The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism by Serris, Alexandra, Stass, Robert, Bignon, Eduardo A., Muena, Nicolás A., Manuguerra, Jean-Claude, Jangra, Rohit K., Li, Sai, Chandran, Kartik, Tischler, Nicole D., Huiskonen, Juha T., Rey, Felix A., Guardado-Calvo, Pablo

“…Hantaviruses are rodent-borne viruses causing serious zoonotic outbreaks worldwide for which no treatment is available. Hantavirus particles are pleomorphic…”
Get full text

Acidification triggers Andes hantavirus membrane fusion and rearrangement of Gc into a stable post-fusion homotrimer by Acuña, Rodrigo, Bignon, Eduardo A, Mancini, Roberta, Lozach, Pierre-Yves, Tischler, Nicole D

“…The hantavirus membrane fusion process is mediated by the Gc envelope glycoprotein from within endosomes. However, little is known about the specific mechanism…”
Get full text