Search Results - "Bighi, F"

Automated Ligand Fishing Using Human Serum Albumin-Coated Magnetic Beads by Moaddel, R, Marszałł, M. P, Bighi, F, Yang, Q, Duan, X, Wainer, I. W

“…Human serum albumin, HSA, was immobilized onto the surface of silica-based magnetic beads. The beads were used to isolate known HSA ligands from a mixture…”
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Pharmacophore modelling of stereoselective binding to the human organic cation transporter (hOCT1) by Moaddel, R, Ravichandran, S, Bighi, F, Yamaguchi, R, Wainer, I W

“…Background and purpose: The human organic cation transporter‐1 (hOCT1) is a polyspecific transporter that plays a role in drug distribution, metabolism and…”
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Stereoselective binding of chiral ligands to single nucleotide polymorphisms of the human organic cation transporter-1 determined using cellular membrane affinity chromatography by Moaddel, R., Bighi, F., Yamaguchi, R., Patel, S., Ravichandran, S., Wainer, I.W.

“…Membranes from stably transfected cell lines that express two point mutations of the human organic cation transporter-1 (hOCT1), R488 M and G465R, have been…”
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Stereoselective Binding of Chiral Ligands to Single Nucleotide Polymorphs (SNPs) of the Human Organic Cation Transporter-1 Determined Using Cellular Membrane Affinity Chromatography by Moaddel, R., Bighi, F., Yamaguchi, R., Patel, S., Ravichandran, S., Wainer, I.W.

“…Membranes from stably transfected cell lines that expresses two point mutations of the human organic cation 1 transporter (hOCT1), R488M and G465R, have been…”
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PIII-66Development of an immobilized human organic cation transporter 1 column for use in on-line screening by BIGHI, F, YAMAGUCHI, R, PATEL, S, HO, P, WAINER, I, MOADDEL, R

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PIII-66 by Bighi, F., Yamaguchi, R., Patel, S., Ho, P., Wainer, I. W., Moaddel, R.

“…BACKGROUND/AIMS To compare a new column based method for characterization of drug‐hOCT1 protein interaction. METHOD We have immobilized the hOCT1 protein onto…”
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