Search Results - "Bieza, Kimberly"

Design, synthesis and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part I by Jiang, Tao, Kuhen, Kelli L., Wolff, Karen, Yin, Hong, Bieza, Kimberly, Caldwell, Jeremy, Bursulaya, Badry, Wu, Tom Yao-Hsing, He, Yun

“…A novel oxindole was discovered as an HIV non-nucleoside reverse transcriptase inhibitor via HTS using a cell-based assay. Systematic structural modifications…”
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Design, synthesis, and biological evaluations of novel oxindoles as HIV-1 non-nucleoside reverse transcriptase inhibitors. Part 2 by Jiang, Tao, Kuhen, Kelli L., Wolff, Karen, Yin, Hong, Bieza, Kimberly, Caldwell, Jeremy, Bursulaya, Badry, Tuntland, Tove, Zhang, Kanyin, Karanewsky, Donald, He, Yun

“…A series of heterocycle-containing oxindoles was synthesized and their HIV antiviral activities were assessed. Some of these analogs exhibited potent…”
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Synthesis and evaluation of N-aryl pyrrolidinones as novel anti-HIV-1 agents. Part 1 by Wu, Baogen, Kuhen, Kelli, Ngoc Nguyen, Truc, Ellis, David, Anaclerio, Beth, He, Xiaohui, Yang, Kunyong, Karanewsky, Donald, Yin, Hong, Wolff, Karen, Bieza, Kimberly, Caldwell, Jeremy, He, Yun

“…N-Aryl pyrrolidinones as novel anti-HIV-1 agents is reported. The synthesis and preliminary structure–activity relationship of a series of pyrrolidinones are…”
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Isolation and characterization of an Arabidopsis thaliana mutant hyper-tolerant to ultraviolet radiation by Bieza, Kimberly Diane

“…Solar ultraviolet radiation is detrimental to most organisms, especially plants, which must be exposed to sunlight for photosynthesis. Plants have evolved…”
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Homogeneous high-throughput screening assays for HIV-1 integrase 3beta-processing and strand transfer activities by Wang, Yu, Klock, Heath, Yin, Hong, Wolff, Karen, Bieza, Kimberly, Niswonger, Kirk, Matzen, Jason, Gunderson, Drew, Hale, Joanna, Lesley, Scott, Kuhen, Kelli, Caldwell, Jeremy, Brinker, Achim

“…HIV-1 integrase (HIV-IN) is a well-validated antiviral drug target catalyzing a multistep reaction to incorporate the HIV-1 provirus into the genome of the…”
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