Search Results - "Bierma, Jan C"
-
1
Novel proteases from the genome of the carnivorous plant Drosera capensis: Structural prediction and comparative analysis
Published in Proteins, structure, function, and bioinformatics (01-10-2016)“…ABSTRACT In his 1875 monograph on insectivorous plants, Darwin described the feeding reactions of Drosera flypaper traps and predicted that their secretions…”
Get full text
Journal Article -
2
Stability of Protein-Specific Hydration Shell on Crowding
Published in Journal of the American Chemical Society (27-04-2016)“…We demonstrate that the effect of protein crowding is critically dependent on the stability of the protein’s hydration shell, which can dramatically vary…”
Get full text
Journal Article -
3
Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis
Published in Cell reports (Cambridge) (29-09-2015)“…Shelterin, a six-member complex, protects telomeres from nucleolytic attack and regulates their elongation by telomerase. Here, we have developed a strategy,…”
Get full text
Journal Article -
4
The Droserasin 1 PSI: A Membrane-Interacting Antimicrobial Peptide from the Carnivorous Plant Drosera capensis
Published in Biomolecules (Basel, Switzerland) (17-07-2020)“…The Droserasins, aspartic proteases from the carnivorous plant , contain a 100-residue plant-specific insert (PSI) that is post-translationally cleaved and…”
Get full text
Journal Article -
5
Protein refractive index increment is determined by conformation as well as composition
Published in Journal of physics. Condensed matter (31-10-2018)“…The refractive index gradient of the eye lens is controlled by the concentration and distribution of its component crystallin proteins, which are highly…”
Get more information
Journal Article -
6
Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication
Published in Biophysical journal (03-08-2021)“…The replication transcription complex (RTC) from the virus SARS-CoV-2 is responsible for recognizing and processing RNA for two principal purposes. The RTC…”
Get full text
Journal Article -
7
Divalent Cations and the Divergence of βγ-Crystallin Function
Published in Biochemistry (Easton) (12-11-2019)“…The βγ-crystallin superfamily contains both β- and γ-crystallins of the vertebrate eye lens and the microbial calcium-binding proteins, all of which are…”
Get full text
Journal Article -
8
Calcium Binding Dramatically Stabilizes an Ancestral Crystallin Fold in Tunicate βγ-Crystallin
Published in Biochemistry (Easton) (20-12-2016)“…The tunicate (Ciona intestinalis) βγ-crystallin represents an intermediate case between the calcium-binding proteins ancestral to the vertebrate βγ-crystallin…”
Get full text
Journal Article -
9
Correlating Conformational Equilibria with Catalysis in the Electron Bifurcating EtfABCX of Thermotoga maritima
Published in Biochemistry (Easton) (02-01-2024)“…Electron bifurcation (BF) is an evolutionarily ancient energy coupling mechanism in anaerobes, whose associated enzymatic machinery remains enigmatic. In…”
Get full text
Journal Article -
10
Controlling Liquid–Liquid Phase Separation of Cold-Adapted Crystallin Proteins from the Antarctic Toothfish
Published in Journal of molecular biology (07-12-2018)“…Liquid–liquid phase separation (LLPS) of proteins is important to a variety of biological processes both functional and deleterious, including the formation of…”
Get full text
Journal Article -
11
γS-Crystallin Proteins from the Antarctic Nototheniid Toothfish: A Model System for Investigating Differential Resistance to Chemical and Thermal Denaturation
Published in The journal of physical chemistry. B (26-11-2014)“…The γS1- and γS2-crystallins, structural eye lens proteins from the Antarctic toothfish (Dissostichus mawsoni), are homologues of the human lens protein…”
Get full text
Journal Article -
12
Cover Image, Volume 84, Issue 10
Published in Proteins, structure, function, and bioinformatics (01-10-2016)Get full text
Journal Article -
13
-
14
Exploring Cold-adapted Eye Lens Proteins and Discovery of an Antimicrobial Protein from a Carnivorous Plant
Published 01-01-2019“…This thesis explores the eye lens proteins from the Antarctic toothfish Dissostichus mawsoni and how they have evolved to the subfreezing temperatures of their…”
Get full text
Dissertation