Search Results - "Bierlmeier, Jan"

Sortase‐Mediated Multi‐Fragment Assemblies by Ligation Site Switching by Bierlmeier, Jan, Álvaro‐Benito, Miguel, Scheffler, Maren, Sturm, Kristina, Rehkopf, Luisa, Freund, Christian, Schwarzer, Dirk

“…Sortase‐mediated ligation (SML) is a powerful tool of protein chemistry allowing the ligation of peptides containing LPxTG sorting motifs and N‐terminal…”
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Asymmetric Disulfanylbenzamides as Irreversible and Selective Inhibitors of Staphylococcus aureus Sortase A by Barthels, Fabian, Marincola, Gabriella, Marciniak, Tessa, Konhäuser, Matthias, Hammerschmidt, Stefan, Bierlmeier, Jan, Distler, Ute, Wich, Peter R., Tenzer, Stefan, Schwarzer, Dirk, Ziebuhr, Wilma, Schirmeister, Tanja

“…Staphylococcus aureus is one of the most frequent causes of nosocomial and community‐acquired infections, with drug‐resistant strains being responsible for…”
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DRP1 interacts directly with BAX to induce its activation and apoptosis by Jenner, Andreas, Peña‐Blanco, Aida, Salvador‐Gallego, Raquel, Ugarte‐Uribe, Begoña, Zollo, Cristiana, Ganief, Tariq, Bierlmeier, Jan, Mund, Markus, Lee, Jason E, Ries, Jonas, Schwarzer, Dirk, Macek, Boris, Garcia‐Saez, Ana J

“…The apoptotic executioner protein BAX and the dynamin‐like protein DRP1 co‐localize at mitochondria during apoptosis to mediate mitochondrial permeabilization…”
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Engineering sortase A by screening a second‐generation library using phage display by Schmohl, Lena, Bierlmeier, Jan, Gerth, Fabian, Freund, Christian, Schwarzer, Dirk

“…Sortase‐mediated ligation is one of the most commonly used chemo‐enzymatic techniques for the site‐specific modification of proteins. We have established a new…”
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Identification of sortase substrates by specificity profiling by Schmohl, Lena, Bierlmeier, Jan, von Kügelgen, Nicolai, Kurz, Leonie, Reis, Pascal, Barthels, Fabian, Mach, Pia, Schutkowski, Mike, Freund, Christian, Schwarzer, Dirk

“…[Display omitted] Sortases catalyze the attachment of surface proteins to the peptidoglycan layer of gram-positive bacteria and further represent powerful…”
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Chemically monoubiquitinated PEX5 binds to the components of the peroxisomal docking and export machinery by Hagmann, Vera, Sommer, Stefanie, Fabian, Patrick, Bierlmeier, Jan, van Treel, Nadine, Mootz, Henning D., Schwarzer, Dirk, Azevedo, Jorge E., Dodt, Gabriele

“…Peroxisomal matrix proteins contain either a peroxisomal targeting sequence 1 (PTS1) or a PTS2 that are recognized by the import receptors PEX5 and PEX7,…”
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Interrogating Substrate Selectivity and Composition of Endogenous Histone Deacetylase Complexes with Chemical Probes by Dose, Alexander, Sindlinger, Julia, Bierlmeier, Jan, Bakirbas, Ahmet, Schulze-Osthoff, Klaus, Einsele-Scholz, Stephanie, Hartl, Markus, Essmann, Frank, Finkemeier, Iris, Schwarzer, Dirk

“…Histone deacetylases (HDACs) regulate the function and activity of numerous cellular proteins by removing acetylation marks from regulatory lysine residues. We…”
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Sortase‐vermittelte Multi‐Fragment‐Kopplung durch Ligationsstellen‐Schaltung by Bierlmeier, Jan, Álvaro‐Benito, Miguel, Scheffler, Maren, Sturm, Kristina, Rehkopf, Luisa, Freund, Christian, Schwarzer, Dirk

“…Die Sortase‐vermittelte Ligation (Engl. sortase‐mediated ligation, SML) ist ein effektives Werkzeug der Proteinchemie, welches die Ligation von Peptiden mit…”
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Probing the structure-activity relationship of endogenous histone deacetylase complexes with immobilized peptide-inhibitors by Sindlinger, Julia, Bierlmeier, Jan, Geiger, Lydia-Christina, Kramer, Katharina, Finkemeier, Iris, Schwarzer, Dirk

“…Histone deacetylases (HDACs) are key regulators of numerous cellular proteins by removing acetylation marks from modified lysine residues. Peptide‐based HDAC…”
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Untersuchung der Substratselektivität und Zusammensetzung endogener Histondeacetylase‐Komplexe durch chemische Sonden by Dose, Alexander, Sindlinger, Julia, Bierlmeier, Jan, Bakirbas, Ahmet, Schulze‐Osthoff, Klaus, Einsele‐Scholz, Stephanie, Hartl, Markus, Essmann, Frank, Finkemeier, Iris, Schwarzer, Dirk

“…Histon‐Deacetylasen (HDACs) regulieren die Funktion und Aktivität von zahlreichen zellulären Proteinen durch die Entfernung von Acetylgruppen an regulatorisch…”
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Untersuchung der Substratselektivität und Zusammensetzung endogener Histondeacetylase-Komplexe durch chemische Sonden by Dose, Alexander, Sindlinger, Julia, Bierlmeier, Jan, Bakirbas, Ahmet, Schulze-Osthoff, Klaus, Einsele-Scholz, Stephanie, Hartl, Markus, Essmann, Frank, Finkemeier, Iris, Schwarzer, Dirk

“…Histon-Deacetylasen (HDACs) regulieren die Funktion und Aktivität von zahlreichen zellulären Proteinen durch die Entfernung von Acetylgruppen an regulatorisch…”
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