Search Results - "Biering, B"

Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism by Puerta-Guardo, Henry, Glasner, Dustin R., Espinosa, Diego A., Biering, Scott B., Patana, Mark, Ratnasiri, Kalani, Wang, Chunling, Beatty, P. Robert, Harris, Eva

“…Flaviviruses cause systemic or neurotropic-encephalitic pathology in humans. The flavivirus nonstructural protein 1 (NS1) is a secreted glycoprotein involved…”
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Targeting by AutophaGy proteins (TAG): Targeting of IFNG-inducible GTPases to membranes by the LC3 conjugation system of autophagy by Park, Sungwoo, Choi, Jayoung, Biering, Scott B., Dominici, Erin, Williams, Lelia E., Hwang, Seungmin

“…LC3 has been used as a marker to locate autophagosomes. However, it is also well established that LC3 can localize on various membranous structures other than…”
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CAPRIN1 Is Required for Control of Viral Replication Complexes by Interferon Gamma by Kurhade, Chaitanya, Kang, Soowon, Biering, Scott B, Hwang, Seungmin, Randall, Glenn

“…Replication complexes (RCs), formed by positive-strand (+) RNA viruses through rearrangements of host endomembranes, protect their replicating RNA from host…”
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The Parasitophorous Vacuole Membrane of Toxoplasma gondii Is Targeted for Disruption by Ubiquitin-like Conjugation Systems of Autophagy by Choi, Jayoung, Park, Sunmin, Biering, Scott B., Selleck, Elizabeth, Liu, Catherine Y., Zhang, Xin, Fujita, Naonobu, Saitoh, Tatsuya, Akira, Shizuo, Yoshimori, Tamotsu, Sibley, L. David, Hwang, Seungmin, Virgin, Herbert W.

“…Autophagy is a lysosomal degradation pathway that is important in cellular homeostasis. Prior work showed a key role for the autophagy related 5 (Atg5) in…”
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An intranasal ASO therapeutic targeting SARS-CoV-2 by Zhu, Chi, Lee, Justin Y., Woo, Jia Z., Xu, Lei, Nguyenla, Xammy, Yamashiro, Livia H., Ji, Fei, Biering, Scott B., Van Dis, Erik, Gonzalez, Federico, Fox, Douglas, Wehri, Eddie, Rustagi, Arjun, Pinsky, Benjamin A., Schaletzky, Julia, Blish, Catherine A., Chiu, Charles, Harris, Eva, Sadreyev, Ruslan I., Stanley, Sarah, Kauppinen, Sakari, Rouskin, Silvi, Näär, Anders M.

“…The COVID-19 pandemic is exacting an increasing toll worldwide, with new SARS-CoV-2 variants emerging that exhibit higher infectivity rates and that may…”
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Unraveling a three-step spatiotemporal mechanism of triggering of receptor-induced Nipah virus fusion and cell entry by Liu, Qian, Stone, Jacquelyn A, Bradel-Tretheway, Birgit, Dabundo, Jeffrey, Benavides Montano, Javier A, Santos-Montanez, Jennifer, Biering, Scott B, Nicola, Anthony V, Iorio, Ronald M, Lu, Xiaonan, Aguilar, Hector C

“…Membrane fusion is essential for entry of the biomedically-important paramyxoviruses into their host cells (viral-cell fusion), and for syncytia formation…”
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Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation by Wang, Chunling, Puerta-Guardo, Henry, Biering, Scott B, Glasner, Dustin R, Tran, Edwina B, Patana, Mark, Gomberg, Trent A, Malvar, Carmel, Lo, Nicholas T N, Espinosa, Diego A, Harris, Eva

“…Arthropod-borne flaviviruses cause life-threatening diseases associated with endothelial hyperpermeability and vascular leak. We recently found that vascular…”
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Viral Replication Complexes Are Targeted by LC3-Guided Interferon-Inducible GTPases by Biering, Scott B., Choi, Jayoung, Halstrom, Rachel A., Brown, Hailey M., Beatty, Wandy L., Lee, Sanghyun, McCune, Broc T., Dominici, Erin, Williams, Lelia E., Orchard, Robert C., Wilen, Craig B., Yamamoto, Masahiro, Coers, Jörn, Taylor, Gregory A., Hwang, Seungmin

“…All viruses with positive-sense RNA genomes replicate on membranous structures in the cytoplasm called replication complexes (RCs). RCs provide an advantageous…”
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The inflammasome pathway is activated by dengue virus non-structural protein 1 and is protective during dengue virus infection by Wong, Marcus P, Juan, Evan Y W, Pahmeier, Felix, Chelluri, Sai S, Wang, Phoebe, Castillo-Rojas, Bryan, Blanc, Sophie F, Biering, Scott B, Vance, Russell E, Harris, Eva

“…Dengue virus (DENV) is a medically important flavivirus causing an estimated 50-100 million dengue cases annually, some of whom progress to severe disease…”
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DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner by Strine, Madison S, Cai, Wesley L, Wei, Jin, Alfajaro, Mia Madel, Filler, Renata B, Biering, Scott B, Sarnik, Sylvia, Chow, Ryan D, Patil, Ajinkya, Cervantes, Kasey S, Collings, Clayton K, DeWeirdt, Peter C, Hanna, Ruth E, Schofield, Kevin, Hulme, Christopher, Konermann, Silvana, Doench, John G, Hsu, Patrick D, Kadoch, Cigall, Yan, Qin, Wilen, Craig B

“…Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further…”
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Practical considerations for Ultraviolet-C radiation mediated decontamination of N95 respirator against SARS-CoV-2 virus by Golovkine, Guillaume R, Roberts, Allison W, Cooper, Chase, Riano, Sebastian, DiCiccio, Angela M, Worthington, Daniel L, Clarkson, Jeffrey P, Krames, Michael, Zhang, Jianping, Gao, Ying, Zhou, Ling, Biering, Scott B, Stanley, Sarah A

“…Decontaminating N95 respirators for reuse could mitigate shortages during the COVID-19 pandemic. Although the United States Center for Disease Control has…”
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The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression by Wei, Jin, Alfajaro, Mia Madel, Cai, Wesley L, Graziano, Vincent R, Strine, Madison S, Filler, Renata B, Biering, Scott B, Sarnik, Sylvia A, Patel, Sonam, Menasche, Bridget L, Compton, Susan R, Konermann, Silvana, Hsu, Patrick D, Orchard, Robert C, Yan, Qin, Wilen, Craig B

“…Identification of host determinants of coronavirus infection informs mechanisms of pathogenesis and may provide novel therapeutic targets. Here, we demonstrate…”
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Discovery of SARS-CoV-2 antiviral synergy between remdesivir and approved drugs in human lung cells by Nguyenla, Xammy, Wehri, Eddie, Van Dis, Erik, Biering, Scott B., Yamashiro, Livia H., Zhu, Chi, Stroumza, Julien, Dugast-Darzacq, Claire, Graham, Thomas G. W., Wang, Xuanting, Jockusch, Steffen, Tao, Chuanjuan, Chien, Minchen, Xie, Wei, Patel, Dinshaw J., Meyer, Cindy, Garzia, Aitor, Tuschl, Thomas, Russo, James J., Ju, Jingyue, Näär, Anders M., Stanley, Sarah, Schaletzky, Julia

“…SARS coronavirus 2 (SARS-CoV-2) has caused an ongoing global pandemic with significant mortality and morbidity. At this time, the only FDA-approved therapeutic…”
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Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2 by Wagoner, Jessica, Herring, Shawn, Hsiang, Tien-Ying, Ianevski, Aleksandr, Biering, Scott B, Xu, Shuang, Hoffmann, Markus, Pöhlmann, Stefan, Gale, Jr, Michael, Aittokallio, Tero, Schiffer, Joshua T, White, Judith M, Polyak, Stephen J

“…Three directly acting antivirals (DAAs) demonstrated substantial reduction in COVID-19 hospitalizations and deaths in clinical trials. However, these agents…”
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N-Glycans on the Nipah Virus Attachment Glycoprotein Modulate Fusion and Viral Entry as They Protect against Antibody Neutralization by BIERING, Scott B, HUANG, Andrew, VU, Andy T, ROBINSON, Lindsey R, BRADEL-TRETHEWAY, Birgit, CHOI, Eric, LEE, Benhur, AGUILAR, Hector C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Flavivirus NS1 Triggers Tissue-Specific Disassembly of Intercellular Junctions Leading to Barrier Dysfunction and Vascular Leak in a GSK-3β-Dependent Manner by Puerta-Guardo, Henry, Biering, Scott B, de Sousa, Francielle Tramontini Gomes, Shu, Jeffrey, Glasner, Dustin R, Li, Jeffrey, Blanc, Sophie F, Beatty, P Robert, Harris, Eva

“…The flavivirus nonstructural protein 1 (NS1) is secreted from infected cells and contributes to endothelial barrier dysfunction and vascular leak in a…”
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Studying the Endothelial Glycocalyx in vitro : What Is Missing? by Haymet, Andrew B, Bartnikowski, Nicole, Wood, Emily S, Vallely, Michael P, McBride, Angela, Yacoub, Sophie, Biering, Scott B, Harris, Eva, Suen, Jacky Y, Fraser, John F

“…All human cells are coated by a surface layer of proteoglycans, glycosaminoglycans (GAGs) and plasma proteins, called the glycocalyx. The glycocalyx transmits…”
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Dengue virus NS1 protein conveys pro‐inflammatory signals by docking onto high‐density lipoproteins by Benfrid, Souheyla, Park, Kyu‐Ho, Dellarole, Mariano, Voss, James E, Tamietti, Carole, Pehau‐Arnaudet, Gérard, Raynal, Bertrand, Brûlé, Sébastien, England, Patrick, Zhang, Xiaokang, Mikhailova, Anastassia, Hasan, Milena, Ungeheuer, Marie‐Noëlle, Petres, Stéphane, Biering, Scott B, Harris, Eva, Sakuntabhai, Anavaj, Buchy, Philippe, Duong, Veasna, Dussart, Philippe, Coulibaly, Fasséli, Bontems, François, Rey, Félix A, Flamand, Marie

“…The dengue virus nonstructural protein 1 (NS1) is a secreted virulence factor that modulates complement, activates immune cells and alters endothelial…”
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One antibody to treat them all by Biering, Scott B

“…Conserved flavivirus protein holds potential as target for versatile vaccines and therapies…”
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The 3-step DLR–ESA Gossamer road to solar sailing by Geppert, U., Biering, B., Lura, F., Block, J., Straubel, M., Reinhard, R.

“…The 3-step Gossamer road map to solar sailing is presented that has been agreed between DLR and ESA in November 2009. The main and exclusive purpose of that…”
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