Search Results - "Bierbower, Sonya M."

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain by Weng, Hao-Jui, Patel, Kush N., Jeske, Nathaniel A., Bierbower, Sonya M., Zou, Wangyuan, Tiwari, Vinod, Zheng, Qin, Tang, Zongxiang, Mo, Gary C.H., Wang, Yan, Geng, Yixun, Zhang, Jin, Guan, Yun, Akopian, Armen N., Dong, Xinzhong

“…TRPA1 and TRPV1 are crucial pain mediators, but how their interaction contributes to persistent pain is unknown. Here, we identify Tmem100 as a potentiating…”
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Activation of mu opioid receptors sensitizes transient receptor potential vanilloid type 1 (TRPV1) via β-arrestin-2-mediated cross-talk by Rowan, Matthew P, Bierbower, Sonya M, Eskander, Michael A, Szteyn, Kalina, Por, Elaine D, Gomez, Ruben, Veldhuis, Nicholas, Bunnett, Nigel W, Jeske, Nathaniel A

“…The transient receptor potential family V1 channel (TRPV1) is activated by multiple stimuli, including capsaicin, acid, endovanilloids, and heat (>42C)…”
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The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K+ Current Amplitudes by Controlling Channel Trafficking by Choveau, Frank S, Zhang, Jie, Bierbower, Sonya M, Sharma, Ramaswamy, Shapiro, Mark S

“…In the central and peripheral nervous system, the assembly of KCNQ3 with KCNQ2 as mostly heteromers, but also homomers, underlies "M-type" currents, a…”
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Pore Helix-S6 Interactions Are Critical in Governing Current Amplitudes of KCNQ3 K+ Channels by Choveau, Frank S., Bierbower, Sonya M., Shapiro, Mark S.

“…Two mechanisms have been postulated to underlie KCNQ3 homomeric current amplitudes, which are small compared with those of KCNQ4 homomers and KCNQ2/Q3…”
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Pore Determinants of KCNQ3 K+ Current Expression by Choveau, Frank S., Hernandez, Ciria C., Bierbower, Sonya M., Shapiro, Mark S.

“…KCNQ3 homomeric channels yield very small macroscopic currents compared with other KCNQ channels or KCNQ2/3 heteromers. Two disparate regions of the…”
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Phosphatidylinositol 4,5-bisphosphate (PIP2) regulates KCNQ3 K+ channels by interacting with four cytoplasmic channel domains by Choveau, Frank S., De la Rosa, Victor, Bierbower, Sonya M., Hernandez, Ciria C., Shapiro, Mark S.

“…Phosphatidylinositol 4,5-bisphosphate (PIP2) in the plasma membrane regulates the function of many ion channels, including M-type (potassium voltage-gated…”
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Examining the effect of iron (ferric) on physiological processes: Invertebrate models by Wagers, Mikaela L., Starks, Ashley, Nadolski, Jeremy, Bierbower, Sonya M., Altenburg, Sean, Schryer, Blake, Cooper, Robin L.

“…Iron is a common and essential element for maintaining life in bacteria, plants and animals and is found in soil, fresh waters and marine waters; however, over…”
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Augmentation of M-type (KCNQ) potassium channels as a novel strategy to reduce stroke-induced brain injury by Bierbower, Sonya M, Choveau, Frank S, Lechleiter, James D, Shapiro, Mark S

“…Cerebral ischemic stroke is a worldwide cause of mortality/morbidity and thus an important focus of research to decrease the severity of brain injury…”
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β-Arrestin-2 Desensitizes the Transient Receptor Potential Vanilloid 1 (TRPV1) Channel by Por, Elaine D., Bierbower, Sonya M., Berg, Kelly A., Gomez, Ruben, Akopian, Armen N., Wetsel, William C., Jeske, Nathaniel A.

“…Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel activated by multiple stimuli and is implicated in a variety of pain…”
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Developmental and behavioral effects in neonatal and adult mice following prenatal activation of endocannabinoid receptors by capsaicin by Perchuk, Alex, Bierbower, Sonya M., Canseco-Alba, Ana, Mora, Zoila, Tyrell, Lauren, Joshi, Neal, Schanz, Norman, Gould, Georgianna G., Onaivi, Emmanuel S.

“…Despite the apparent abundance of ligand-gated transient receptor potential vanilloid type 1 (TRPV1) and possible cross talk between the endocannabinoid and…”
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Parasite-related modification of mating behaviour and refuge use in the aquatic isopod Caecidotea intermedius: neurological correlates by Kopp, Darin A, Bierbower, Sonya M, Murphy, Alexandrea D, Mormann, Kimberly, Sparkes, Timothy C

“…The acanthocephalan Acanthocephalus dirus is a trophically transmitted parasite that infects freshwater isopods as intermediate hosts and fish as definitive…”
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The Mechanistic Action of Carbon Dioxide on a Neural Circuit and NMJ Communication by BIERBOWER, SONYA M., COOPER, ROBIN L.

“…ABSTRACT Previous studies examining behavioral responses to CO2 revealed that high [CO2] acts as a natural repellent in a concentration dependent manner for…”
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Förster resonance energy transfer-based imaging at the cell surface of live cells by Bierbower, Sonya M, Shapiro, Mark S

“…Understanding the molecular mechanisms of protein-protein interactions at the cell surface of living cells is fundamental to identifying the nature of cellular…”
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Comparative study of environmental factors influencing motor task learning and memory retention in sighted and blind crayfish by Bierbower, Sonya M., Shuranova, Zhanna P., Viele, Kert, Cooper, Robin L.

“…In classical conditioning, an alteration in response occurs when two stimuli are regularly paired in close succession. An area of particular research interest…”
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Measures of heart and ventilatory rates in freely moving crayfish by Bierbower, Sonya M, Cooper, Robin L

“…The fear, flight or fight response serves as the fundamental physiological basis for examining an organism's awareness of its environment under an impending…”
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PARASITE-RELATED PAIRING SUCCESS IN AN INTERMEDIATE HOST, CAECIDOTEA INTERMEDIUS (ISOPODA): EFFECTS OF MALE BEHAVIOR AND REPRODUCTIVE PHYSIOLOGY by Bierbower, Sonya M, Sparkes, Timothy C

“…The acanthocephalan parasite Acanthocephalus dirus develops from the egg to the cystacanth stage inside the freshwater isopod Caecidotea intermedius. We have…”
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Cow cuddling: Cognitive considerations in bovine-assisted therapy by Compitus, Katherine, Bierbower, Sonya M.

“…Abstract Animal-assisted therapy (AAT) is an integrative model frequently used in conjunction with other modalities such as psychodynamic psychotherapy and…”
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The Role of the Carboxyl Terminus Helix C-D Linker in Regulating KCNQ3 K.sup.+ Current Amplitudes by Controlling Channel Trafficking by Choveau, Frank S, Zhang, Jie, Bierbower, Sonya M, Sharma, Ramaswamy, Shapiro, Mark S

“…In the central and peripheral nervous system, the assembly of KCNQ3 with KCNQ2 as mostly heteromers, but also homomers, underlies "M-type" currents, a…”
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The Effects of Bacterial Endotoxin (LPS) on Cardiac and Neural Function in Various Animal Models by Cooper, Robin Lewis, McNabb, Micaiah, Saelinger, Christa, Greenhalgh, Abigail, Istas, Oscar, Stanback, Maddie, Stanback, Stanback, Anyagaligbo, Ogechi, Bernard, Jate, Danley, Melody L, Bierbower, Sonya M, Ghoweri, Adam, Thibault, Olivier

“…The endotoxic effect from gram negative bacteria is primarily due to the lipopolysaccharides (LPS). LPS activates the innate immune response through a…”
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M‐type K+ Channel Openers: In vivo Neuroprotective Role during Cerebrovascular Stroke by Bierbower, Sonya M, Choveau, Frank, Shapiro, Mark S.

“…Abstract only Stroke is the third leading cause of human death and many models have been used to study the mechanisms of tissue damage and neuronal protection…”
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