Search Results - "Bielinski, Suzette"

Assessing document section heterogeneity across multiple electronic health record systems for computational phenotyping: A case study of heart-failure phenotyping algorithm by Moon, Sungrim, Liu, Sijia, Kshatriya, Bhavani Singh Agnikula, Fu, Sunyang, Moser, Ethan D, Bielinski, Suzette J, Fan, Jungwei, Liu, Hongfang

“…The incorporation of information from clinical narratives is critical for computational phenotyping. The accurate interpretation of clinical terms highly…”
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Development and Validation of a Protein Risk Score for Mortality in Heart Failure : A Community Cohort Study by Kuku, Kayode O, Shearer, Joseph J, Hashemian, Maryam, Oyetoro, Rebecca, Park, Hoyoung, Dulek, Brittany, Bielinski, Suzette J, Larson, Nicholas B, Ganz, Peter, Levy, Daniel, Psaty, Bruce M, Joo, Jungnam, Roger, Véronique L

“…Heart failure (HF) is a complex clinical syndrome with high mortality. Current risk stratification approaches lack precision. High-throughput proteomics could…”
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Pharmacogenomics of Medication‐Induced Weight Gain and Antiobesity Medications by Singh, Sneha, Ricardo‐Silgado, Maria L., Bielinski, Suzette J., Acosta, Andres

“…Obesity is a chronic, multifactorial disease associated with a large number of comorbidities. The clinical management of obesity involves a stepwise integrated…”
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A model-based cost-effectiveness analysis of pharmacogenomic panel testing in cardiovascular disease management: preemptive, reactive, or none? by Zhu, Ye, Moriarty, James P., Swanson, Kristi M., Takahashi, Paul Y., Bielinski, Suzette J., Weinshilboum, Richard, Wang, Liewei, Borah, Bijan J.

“…Purpose Pharmacogenomics (PGx) studies how inherited genetic variations in individuals affect drug absorption, distribution, and metabolism. PGx panel testing…”
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Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data by Denny, Joshua C, Bastarache, Lisa, Ritchie, Marylyn D, Carroll, Robert J, Zink, Raquel, Mosley, Jonathan D, Field, Julie R, Pulley, Jill M, Ramirez, Andrea H, Bowton, Erica, Basford, Melissa A, Carrell, David S, Peissig, Peggy L, Kho, Abel N, Pacheco, Jennifer A, Rasmussen, Luke V, Crosslin, David R, Crane, Paul K, Pathak, Jyotishman, Bielinski, Suzette J, Pendergrass, Sarah A, Xu, Hua, Hindorff, Lucia A, Li, Rongling, Manolio, Teri A, Chute, Christopher G, Chisholm, Rex L, Larson, Eric B, Jarvik, Gail P, Brilliant, Murray H, McCarty, Catherine A, Kullo, Iftikhar J, Haines, Jonathan L, Crawford, Dana C, Masys, Daniel R, Roden, Dan M

“…When applied in large scale to electronic medical record data, the PheWAS approach replicates GWAS associations and reveals potentially new pleiotropic…”
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Systematic review of the evidence on the cost-effectiveness of pharmacogenomics-guided treatment for cardiovascular diseases by Zhu, Ye, Swanson, Kristi M., Rojas, Ricardo L., Wang, Zhen, St. Sauver, Jennifer L., Visscher, Sue L., Prokop, Larry J., Bielinski, Suzette J., Wang, Liewei, Weinshilboum, Richard, Borah, Bijan J.

“…To examine the evidence on the cost-effectiveness of implementing pharmacogenomics (PGx) in cardiovascular disease (CVD) care. We conducted a systematic review…”
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Atrial Fibrillation and Death After Myocardial Infarction A Community Study by JABRE, Patricia, JOUVEN, Xavier, ADNET, Frederic, THABUT, Gabriel, BIELINSKI, Suzette J, WESTON, Susan A, ROGER, Veronique L

“…Atrial fibrillation (AF) often coexists with myocardial infarction (MI), yet its prognostic influence is disputed. Prior reports studied the relationship of AF…”
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The association of microvascular disease and endothelial dysfunction with vertebral trabecular bone mineral density by Barzilay, Joshua I, Buzkova, Petra, Bielinski, Suzette J, Cotch, Mary Frances, Kestenbaum, Bryan, Austin, Thomas R, Carbone, Laura, Mukamal, Kenneth J, Budoff, Matthew J

“…SummaryRetinopathy and albuminuria are associated with hip fracture risk. We investigated whether these disorders and endothelial dysfunction (which underlies…”
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The association of microvascular disease and endothelial dysfunction with vertebral trabecular bone mineral density: The MESA study by Barzilay, Joshua I., Buzkova, Petra, Bielinski, Suzette J., Cotch, Mary Frances, Kestenbaum, Bryan, Austin, Thomas R., Carbone, Laura, Mukamal, Kenneth J., Budoff, Matthew J.

“…Summary Retinopathy and albuminuria are associated with hip fracture risk. We investigated whether these disorders and endothelial dysfunction (which underlies…”
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Predicting Alzheimer's Disease and Related Dementias in Heart Failure and Atrial Fibrillation by Manemann, Sheila M., Chamberlain, Alanna M., Bielinski, Suzette J., Jiang, Ruoxiang, Weston, Susan A., Roger, Véronique L.

“…The Framingham Heart Study Dementia Risk Score (FDRS) was developed in a general population of older persons. It is unknown how the FDRS variables predict…”
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Electronic medical records for genetic research: results of the eMERGE consortium by Kho, Abel N, Pacheco, Jennifer A, Peissig, Peggy L, Rasmussen, Luke, Newton, Katherine M, Weston, Noah, Crane, Paul K, Pathak, Jyotishman, Chute, Christopher G, Bielinski, Suzette J, Kullo, Iftikhar J, Li, Rongling, Manolio, Teri A, Chisholm, Rex L, Denny, Joshua C

“…Clinical data in electronic medical records (EMRs) are a potential source of longitudinal clinical data for research. The Electronic Medical Records and…”
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Variants Near FOXE1 Are Associated with Hypothyroidism and Other Thyroid Conditions: Using Electronic Medical Records for Genome- and Phenome-wide Studies by Denny, Joshua C., Crawford, Dana C., Ritchie, Marylyn D., Bielinski, Suzette J., Basford, Melissa A., Bradford, Yuki, Chai, High Seng, Bastarache, Lisa, Zuvich, Rebecca, Peissig, Peggy, Carrell, David, Ramirez, Andrea H., Pathak, Jyotishman, Wilke, Russell A., Rasmussen, Luke, Wang, Xiaoming, Pacheco, Jennifer A., Kho, Abel N., Hayes, M. Geoffrey, Weston, Noah, Matsumoto, Martha, Kopp, Peter A., Newton, Katherine M., Jarvik, Gail P., Li, Rongling, Manolio, Teri A., Kullo, Iftikhar J., Chute, Christopher G., Chisholm, Rex L., Larson, Eric B., McCarty, Catherine A., Masys, Daniel R., Roden, Dan M., de Andrade, Mariza

“…We repurposed existing genotypes in DNA biobanks across the Electronic Medical Records and Genomics network to perform a genome-wide association study for…”
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Integrating pharmacogenomics into clinical practice: promise vs reality by St. Sauver, Jennifer L., PhD, Bielinski, Suzette J., PhD, Olson, Janet E., PhD, Bell, Elizabeth J., PhD, Mc Gree, Michaela E, Jacobson, Debra J., MS, McCormick, Jennifer B., PhD, Caraballo, Pedro J., MD, Takahashi, Paul Y., MD, Roger, Veronique L., MD, Rohrer Vitek, Carolyn R

“…Abstract Background Limited information is available regarding primary care clinicians’ response to pharmacogenomic Clinical Decision Support (PGx-CDS) alerts…”
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Sex Differences in Outcomes After Myocardial Infarction in the Community by Asleh, Rabea, Manemann, Sheila M., Weston, Susan A., Bielinski, Suzette J., Chamberlain, Alanna M., Jiang, Ruoxiang, Gerber, Yariv, Roger, Véronique L.

“…Prior studies observed that women experienced worse outcomes than men after myocardial infarction but did not convincingly establish an independent effect of…”
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Atherosclerotic Cardiovascular Disease Risk Stratification Based on Measurements of Troponin and Coronary Artery Calcium by Sandoval, Yader, Bielinski, Suzette J., Daniels, Lori B., Blaha, Michael J., Michos, Erin D., DeFilippis, Andrew P., Szklo, Moyses, deFilippi, Christopher, Larson, Nicholas B., Decker, Paul A., Jaffe, Allan S.

“…Low values of high-sensitivity cardiac troponin (hs-cTn) and coronary artery calcium (CAC) scores of zero are associated with a low risk for atherosclerotic…”
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Comparing outcomes and costs among warfarin-sensitive patients versus warfarin-insensitive patients using The Right Drug, Right Dose, Right Time: Using genomic data to individualize treatment (RIGHT) 10K warfarin cohort by Swanson, Kristi M, Zhu, Ye, Rojas, Ricardo L, St Sauver, Jennifer L, Bielinski, Suzette J, Jacobsen, Debra J, Visscher, Sue L, Wang, Liewei, Weinshilboum, Richard, Borah, Bijan J

“…Oral anticoagulant (OAC) therapy has been the main treatment approach for stroke prevention for decades. Warfarin is the most widely prescribed OAC in the…”
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A favorable cardiometabolic profile is associated with the G allele of the genetic variant rs5068 in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA) by Cannone, Valentina, Scott, Christopher G, Decker, Paul A, Larson, Nicholas B, Palmas, Walter, Taylor, Kent D, Wang, Thomas J, Gupta, Deepak K, Bielinski, Suzette J, Burnett, Jr, John C

“…In whites, the minor G allele of the atrial natriuretic peptide (ANP) genetic variant rs5068 is associated with higher circulating levels of ANP and B-type…”
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Recent trends in cardiovascular disease deaths: a state specific perspective by Manemann, Sheila M, Gerber, Yariv, Bielinski, Suzette J, Chamberlain, Alanna M, Margolis, Karen L, Weston, Susan A, Killian, Jill M, Roger, Véronique L

“…Abstract Background The rate of decline in cardiovascular disease (CVD) mortality has lessened nationally. How these findings apply to specific states or…”
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Validation of electronic medical record-based phenotyping algorithms: results and lessons learned from the eMERGE network by Newton, Katherine M, Peissig, Peggy L, Kho, Abel Ngo, Bielinski, Suzette J, Berg, Richard L, Choudhary, Vidhu, Basford, Melissa, Chute, Christopher G, Kullo, Iftikhar J, Li, Rongling, Pacheco, Jennifer A, Rasmussen, Luke V, Spangler, Leslie, Denny, Joshua C

“…Genetic studies require precise phenotype definitions, but electronic medical record (EMR) phenotype data are recorded inconsistently and in a variety of…”
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Electrophysiological and Hemodynamic Characteristics Associated With Obesity in Patients With Atrial Fibrillation by Munger, Thomas M., MD, Dong, Ying-Xue, MD, PhD, Masaki, Mitsuru, MD, PhD, Oh, Jae K., MD, Mankad, Sunil V., MD, Borlaug, Barry A., MD, Asirvatham, Samuel J., MD, Shen, Win-Kuang, MD, Lee, Hon-Chi, MD, PhD, Bielinski, Suzette J., PhD, Hodge, David O., MS, Herges, Regina M., BS, Buescher, Traci L., RN, Wu, Jia-Hui, MD, Ma, Changsheng, MD, Zhang, Yanhua, MD, Chen, Peng-Sheng, MD, Packer, Douglas L., MD, Cha, Yong-Mei, MD

“…Objectives The authors sought to characterize the left atrial (LA) and pulmonary vein (PV) electrophysiological and hemodynamic features in obese patients with…”
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