Search Results - "Bieler, J G"

Increased TCR avidity after T cell activation: a mechanism for sensing low-density antigen by Fahmy, T M, Bieler, J G, Edidin, M, Schneck, J P

“…While activated T cells are known to have enhanced biological responses to antigen stimulation, the biophysical basis of this increased sensitivity remains…”
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Expression of CR1/2 receptor on alloantigen-stimulated mouse T cells by Qian, Z., Bieler, J.G., Baldwin, W.M., Wasowska, B.A.

“…Antibodies can mediate injury of organ transplants by several mechanisms, including complement activation and interaction with Fc receptors on cells. We tested…”
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Probing T cell membrane organization using dimeric MHC–Ig complexes by Fahmy, Tarek M, Bieler, Joan G, Schneck, Jonathan P

“…In this report, we review a novel method for probing the membrane organization of T cells using dimeric major histocompatibility complexes (MHC), MHC–Ig…”
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Analysis of the expression of peptide-major histocompatibility complexes using high affinity soluble divalent T cell receptors by O'Herrin, S M, Lebowitz, M S, Bieler, J G, al-Ramadi, B K, Utz, U, Bothwell, A L, Schneck, J P

“…Understanding the regulation of cell surface expression of specific peptide-major histocompatibility complex (MHC) complexes is hindered by the lack of direct…”
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Soluble, High-Affinity Dimers of T-Cell Receptors and Class II Major Histocompatibility Complexes: Biochemical Probes for Analysis and Modulation of Immune Responses by Lebowitz, Michael S., O'Herrin, Sean M., Hamad, Abdel-Rahim A., Fahmy, Tarek, Marguet, Didier, Barnes, Nicholas C., Pardoll, Drew, Bieler, Joan G., Schneck, Jonathan P.

“…T cell receptors (TCR) and major histocompatibility complex (MHC) molecules are integral membrane proteins that have central roles in cell-mediated immune…”
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Ex vivo induction and expansion of natural killer T cells by CD1d1-Ig coated artificial antigen presenting cells by Webb, Tonya J., Bieler, Joan G., Schneck, Jonathan P., Oelke, Mathias

“…Natural killer T (NKT) cells play a pivotal role in maintaining immune homostasis. They recognize lipid antigen in the context of CD1d molecules and…”
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Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response by Ercolini, Anne M, Ladle, Brian H, Manning, Elizabeth A, Pfannenstiel, Lukas W, Armstrong, Todd D, Machiels, Jean-Pascal H, Bieler, Joan G, Emens, Leisha A, Reilly, R Todd, Jaffee, Elizabeth M

“…A major barrier to successful antitumor vaccination is tolerance of high-avidity T cells specific to tumor antigens. In keeping with this notion, HER-2/neu…”
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Increased TCR Avidity after T Cell Activation: A Mechanism for Sensing Low-Density Antigen by Fahmy, T M, Bieler, J G, Edidin, M, Schneck, J P

“…While activated T cells are known to have enhanced biological responses to antigen stimulation, the biophysical basis of this increased sensitivity remains…”
Get full text