Search Results - "Bielefeld, E C"

Systemic gene delivery transduces the enteric nervous system of guinea pigs and cynomolgus macaques by Gombash, S E, Cowley, C J, Fitzgerald, J A, Lepak, C A, Neides, M G, Hook, K, Todd, L J, Wang, G-D, Mueller, C, Kaspar, B K, Bielefeld, E C, Fischer, A J, Wood, J D, Foust, K D

“…Characterization of adeno-associated viral vector (AAV) mediated gene delivery to the enteric nervous system (ENS) was recently described in mice and rats. In…”
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The Role of Oxidative Stress in Noise-Induced Hearing Loss by Henderson, Donald, Bielefeld, Eric C, Harris, Kelly Carney, Hu, Bo Hua

“…Modern research has provided new insights into the biological mechanisms of noise-induced hearing loss, and with these new insights comes hope for possible…”
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An Src-protein tyrosine kinase inhibitor to reduce cisplatin ototoxicity while preserving its antitumor effect by Bielefeld, Eric C, Tanaka, Chiemi, Chen, Guang-di, Coling, Donald, Li, Manna, Henderson, Donald, Fetoni, Anna R

“…Ototoxicity remains a major dose-limiting side effect of cisplatin. The current studies were carried out to evaluate the effectiveness of a novel Src-protein…”
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Postexposure treatment with a Src-PTK inhibitor in combination with N-l-acetyl cysteine to reduce noise-induced hearing loss by Bielefeld, Eric C, Wantuck, Rebecca, Henderson, Donald

“…Both the antioxidant, N-l-acetyl cysteine (NAC), and the Src inhibitor, KX1-004, have been used to protect the cochlea from hazardous noise. In order to extend…”
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A comparison of the protective effects of systemic administration of a pro-glutathione drug and a Src-PTK inhibitor against noise-induced hearing loss by Bielefeld, Eric C, Hynes, Sarah, Pryznosch, David, Liu, Jianzhong, Coleman, John Km, Henderson, Donald

“…Both the antioxidant, n-l-acetyl cysteine (L-NAC) and the Src inhibitor, KX1-004, have been used to protect the cochlea from hazardous noise. To date, KX1-004…”
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A comparison of the protective effects of systemic administration of a pro-giutathione drug and a Src-PTK inhibitor against noise-induced hearing loss by Bielefeld, E C, Hynes, S, Pryznosch, D, Liu, J, Coleman, JKM, Henderson, D

“…Both the antioxidarit, n-l-acetyl cysteine (L-NAC) and the Src inhibitor, KX1-004, have been used to protect the cochlea from hazardous noise. To date, KX1-004…”
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The role of oxidative stress in noise-induced hearing loss by Henderson, D, Bielefeld, E, Harris, K, Hu, B

“…Interventions are discussed that target the prevention of noise-induced hair cell death: the use of antioxidants to scavenge and eliminate the damaging ROS,…”
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Damage and threshold shift resulting from cochlear exposure to Paraquat-generated superoxide by Bielefeld, Eric C., Hu, Bo Hua, Harris, Kelly Carney, Henderson, Donald

“…Superoxide has been implicated as a contributing factor to cochlear pathology from a number of sources, including noise and ototoxic drugs. The effects of…”
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