Search Results - "Biela, Artur"
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Conserved structures and dynamics in 5'-proximal regions of Betacoronavirus RNA genomes
Published in Nucleic acids research (12-04-2024)“…Betacoronaviruses are a genus within the Coronaviridae family of RNA viruses. They are capable of infecting vertebrates and causing epidemics as well as global…”
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2
An ultra-stable gold-coordinated protein cage displaying reversible assembly
Published in Nature (London) (01-05-2019)“…Symmetrical protein cages have evolved to fulfil diverse roles in nature, including compartmentalization and cargo delivery 1 , and have inspired synthetic…”
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3
Cryo-EM structure of human eIF5A-DHS complex reveals the molecular basis of hypusination-associated neurodegenerative disorders
Published in Nature communications (27-03-2023)“…Hypusination is a unique post-translational modification of the eukaryotic translation factor 5A (eIF5A) that is essential for overcoming ribosome stalling at…”
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ERK1/2 interaction with DHPS regulates eIF5A deoxyhypusination independently of ERK kinase activity
Published in Cell reports (Cambridge) (22-10-2024)“…This study explores a non-kinase effect of extracellular regulated kinases 1/2 (ERK1/2) on the interaction between deoxyhypusine synthase (DHPS) and its…”
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Artificial Protein Cage with Unusual Geometry and Regularly Embedded Gold Nanoparticles
Published in Nano letters (27-04-2022)“…Artificial protein cages have great potential in a number of areas including cargo capture and delivery and as artificial vaccines. Here, we investigate an…”
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6
Programmable polymorphism of a virus-like particle
Published in Communications materials (07-02-2022)“…Virus-like particles (VLPs) have significant potential as artificial vaccines and drug delivery systems. The ability to control their size has wide ranging…”
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Chemically induced protein cage assembly with programmable opening and cargo release
Published in Science advances (07-01-2022)“…Engineered protein cages are promising tools that can be customized for applications in medicine and nanotechnology. A major challenge is developing a…”
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Thiopurine Derivative-Induced Fpg/Nei DNA Glycosylase Inhibition: Structural, Dynamic and Functional Insights
Published in International journal of molecular sciences (17-03-2020)“…DNA glycosylases are emerging as relevant pharmacological targets in inflammation, cancer and neurodegenerative diseases. Consequently, the search for…”
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Shape-Morphing of an Artificial Protein Cage with Unusual Geometry Induced by a Single Amino Acid Change
Published in ACS Nanoscience Au (19-10-2022)“…Artificial protein cages are constructed from multiple protein subunits. The interaction between the subunits, notably the angle formed between them, controls…”
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Prawne i środowiskowe aspekty rozwoju zielonej infrastruktury miast w dobie zmian klimatu na przykładzie dachów zielonych
Published in Prawne Problemy Górnictwa i Ochrony Środowiska (01-01-2024)“…W niniejszej pracy zestawiono środowiskowy i prawny aspekt rozwoju zielonej infrastruktury na terenach miejskich, ze szczególnym uwzględnieniem dachów…”
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Towards understanding the effect of high pressure on food protein allergenicity: β-lactoglobulin structural studies
Published in Food chemistry (01-01-2019)“…•An important food protein β-lactoglobulin in crystal state under pressure of 550 MPa was investigated.•High pressure noticeably modified β-lactoglobulin…”
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Artificial Protein Cages Assembled via Gold Coordination
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Artificial protein cages made from multiple copies of a single protein can be produced such that they only assemble upon addition of a metal ion. Consequently,…”
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Wybrane aspekty prawne decyzji zezwalającej na wycinkę drzew i krzewów
Published in Prawne Problemy Górnictwa i Ochrony Środowiska (01-07-2020)“…Organ administracji, wydając, na podstawie art. 83 ustawy z dnia 16 kwietnia 2004 r. o ochronie przyrody, zezwolenie na usunięcie drzew lub krzewów musi…”
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Prawne i środowiskowe aspekty rozwoju zielonej infrastruktury miast w dobie zmian klimatu na przykładzie dachów zielonych
Published in Prawne Problemy Górnictwa i Ochrony Środowiska (2023)“…This paper explores the environmental and legal aspects of green infrastructure, focusing specifically on green roofs in urban areas. The study highlights the…”
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Wybrane aspekty prawne decyzji zezwalającej na usunięcie drzew i krzewów
Published in Prawne Problemy Górnictwa i Ochrony Środowiska (2019)“…When an administrative authority issues a permit to remove trees or shrubs pursuant to Article 83 of the Nature Conservation Act, it must face regulations that…”
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The influence of the essential oil extracted from hops on monolayers and bilayers imitating plant pathogen bacteria membranes
Published in Colloids and surfaces, B, Biointerfaces (01-01-2019)“…[Display omitted] •Among over 100 volatile compounds in the hop essential oil β-myrcene dominates.•The hop essential oil incorporates into lipid monolayers and…”
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Effect of pressure on the crystal structure and adsorption of β-lactoglobulin
Published in Acta crystallographica. Section A, Foundations and advances (22-08-2018)“…Abstract only…”
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Synthesis of amide and sulfonamide substituted N-aryl 6-aminoquinoxalines as PFKFB3 inhibitors with improved physicochemical properties
Published in Bioorganic & medicinal chemistry letters (15-02-2019)“…[Display omitted] In oncology, the “Warburg effect” describes the elevated production of energy by glycolysis in cancer cells. The ubiquitous and…”
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Abstract 442: Small molecule inhibitors of SHMT1/2 validate serine metabolism as a target in the treatment of c-Myc positive solid tumors
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Many oncogenes modulate metabolic pathways and altered metabolism is one of the hallmarks of cancer. In order to sustain proliferation, cell growth…”
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Discovery and Structure–Activity Relationships of N‐Aryl 6‐Aminoquinoxalines as Potent PFKFB3 Kinase Inhibitors
Published in ChemMedChem (08-01-2019)“…Energy and biomass production in cancer cells are largely supported by aerobic glycolysis in what is called the Warburg effect. The process is regulated by key…”
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