Search Results - "Bieg, Tadeusz"
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The melibiose-derived glycation product mimics a unique epitope present in human and animal tissues
Published in Scientific reports (03-02-2021)“…Non-enzymatic modification of proteins by carbohydrates, known as glycation, leads to generation of advanced glycation end-products (AGEs). In our study we…”
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2
Synthesis and cytotoxicity of 2,3-enopyranosyl C-linked conjugates of genistein
Published in Molecules (Basel, Switzerland) (30-05-2014)“…A series of glycoconjugates, derivatives of genistein containing a C-glycosylated carbohydrate moiety, were synthesized and their anticancer activity was…”
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3
Synthesis and preliminary biological evaluations of 5'-substituted derivatives of uridine as glycosyltransferase inhibitors
Published in Molecules (Basel, Switzerland) (08-07-2013)“…New derivatives of uridine which contain a b-ketoenol motif were synthesized, characterized and biologically tested. Synthesized compounds 1-4 showed no…”
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4
Simultaneous Removal of Benzyl and Benzyloxycarbonyl Protective Groups in 5′-O-(2-Deoxy-α-D-Glucopyranosyl)Uridine by Catalytic Transfer Hydrogenolysis
Published in Nucleosides, nucleotides & nucleic acids (01-12-2008)“…Synthesis of N 3 ,2′,3′-O-tris-(benzyloxycarbonyl)uridine and its use in the synthesis of 5′-O-(2-deoxy-α-d-glucopyranosyl)uridine is described. Simultaneous…”
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5
Highly selective synthesis of ( E)- N-aryl- N-(1-propenyl) ethanamides via isomerization of N-allyl ethanamides catalyzed by ruthenium complexes
Published in Tetrahedron letters (01-10-2001)“…A convenient and highly selective method of synthesis of ( E)- N-aryl- N-(1-propenyl)ethanamides via isomerization of respective N-allyl- N-arylethanamides…”
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6
Spectroscopic study on the inclusion complexes of β-cyclodextrin with selected metabolites of catecholamines
Published in Journal of molecular structure (05-01-2017)“…Inclusion complexes formed between β-cyclodextrin (β-CD) and metabolites of catecholamines, i.e. vanillylmandelic acid (VMA), homovanillic acid (HVA) as well…”
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7
4- O-Acetyl-3- O- tert-butyldimethylsilyl- l-rhamnal: a building block in the stereoselective synthesis of 2-deoxy-α- l-rhamnopyranosides
Published in Carbohydrate research (27-11-2006)“…The stereoselective synthesis of 2-deoxy-α- l-glycosides by addition of various acceptors to 4- O-acetyl-3- O- tert-butyldimethylsilyl- l-rhamnal promoted by…”
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8
Thermoresponsive microgels containing trehalose as soft matrices for 3D cell culture
Published in Biomaterials science (31-01-2017)“…A series of thermoresponsive glycomicrogels with trehalose in the cross-links or with trehalose in the cross-links and as pending moieties was synthesized…”
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9
New N-substituted hydrazones, derivatives of uridyl aldehyde
Published in Nucleosides, nucleotides & nucleic acids (04-03-2017)“…N-substituted isomeric hydrazones of uridyl aldehyde have been synthesized. The occurrence of the dominant E isomers with respect to the azomethine group was…”
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10
An approach for disaccharide chiron synthesis using a Ferrier-type rearrangement
Published in Tetrahedron letters (02-07-2014)“…We report a new approach for the synthesis of new chiral synthons in which two unsaturated sugars are linked via a glycosidic bond. The di-unsaturated…”
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11
Adducts of uridine and glycals as potential substrates for glycosyltransferases
Published in Bioorganic chemistry (01-10-2007)“…We report on the synthesis of 2-deoxyglycosyl derivatives of uridine as potential donor substrates for glycosyltransferases. The totally stereoselective…”
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12
New monomeric and dimeric uridinyl derivatives as inhibitors of chitin synthase
Published in Bioorganic chemistry (01-08-2015)“…[Display omitted] •New dimeric and monomeric amide derivatives of uridine have been synthesized.•Compound 7 showed activities against several fungal strains…”
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13
Synthesis of 2-deoxy-hexopyranosyl derivatives of uridine as donor substrate analogues for glycosyltransferases
Published in Bioorganic chemistry (01-12-2009)“…A series of UDP-sugar analogues were synthesized and tested as inhibitors against bovine β-1,4-galactosyltransferase I in fluorescent assays. A series of…”
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14
5-Amino-2-pyridyl 1-thioglycosides in synthesis of analogs of glycosyltransferases substrates
Published in Bioorganic chemistry (01-06-2009)“…We present the synthesis of 1-thioglycosyl derivatives of uridine, which were designed to act as potential donor substrates for glycosyltransferases. We…”
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15
Synthesis and biological evaluation of 5′-glycyl derivatives of uridine as inhibitors of 1,4-β-galactosyltransferase
Published in Bioorganic chemistry (01-02-2015)“…•New 5′-O-glycyl and 5′-N-glycyl derivatives of uridine were synthesized.•Compound A4 showed moderate inhibition against 1,4-β-galactosyltransferase.•STD NMR…”
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16
Abstract 13796: 1Hnmr Spectroscopy Reveals Only Subtle Differences Between Serum Metabolome of Metabolically Healthy Obese Subjects and Subjects With Metabolic Syndrome
Published in Circulation (New York, N.Y.) (19-11-2019)“…IntroductionObesity is a component of metabolic health assessment and metabolic syndrome (MetS) diagnosis. In recent years, concept of 'metabolically healthy…”
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17
Microwave-Assisted Regioselective Benzylation: An Access to Glycal Derivatives with a Free Hydroxyl Group at C4
Published in Journal of carbohydrate chemistry (01-09-2012)“…D-glucal, D-galactal, and their 6-O-TBDMS derivatives were benzylated in a two-step procedure under microwave conditions. In the first step glycals were…”
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18
Isomerisation of N-allyl- N-arylethanamides catalysed by ruthenium complexes
Published in Journal of molecular catalysis. A, Chemical (24-10-2002)“…Isomerisation of N-allyl- N-arylethanamides (MeCON(AR)allyl) catalysed by [RuClH(CO)(PPh 3) 3] has been studied. It is suggested that the observed selectivity…”
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19
Double bond migration in Sallyl systems catalysed by [RuClH(CO)(PPh 3) 3]
Published in Journal of organometallic chemistry (03-01-2003)“…Reactions of Sallyl systems (allyl sulphides of RSallyl type, where R=Et, allyl, Ph, Me 3C, Ph 3C, as well as of allyl phenyl sulphoxide, allyl phenyl…”
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20
Cleavage of different ether bonds in butyl glycidyl ether and allyl glycidyl ether by K −, K +(15-crown-5) 2
Published in Journal of organometallic chemistry (22-10-2002)“…The kind of substituent in alkyl glycidyl ethers affects the course of their reaction with K −, K +(15-crown-5) 2. The cyclic oxirane ring is exclusively…”
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