Search Results - "Biddle, Kathleen E"

Opinion on the Optimal Histologic Evaluation of the Bone Marrow in Nonclinical Toxicity Studies by Biddle, Kathleen E.

“…Identification of bone marrow toxicity is an important issue in drug development and toxicologic pathologists play a critical role in that identification…”
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Liver Toxicity Observed With Lorlatinib When Combined With Strong CYP3A Inducers: Evaluation of Cynomolgus Monkey as a Nonclinical Model for Assessing the Mechanism of Combinational Toxicity by Hu, Wenyue, Lettiere, Daniel, Tse, Susanna, Johnson, Theodore R, Biddle, Kathleen E, Thibault, Stephane, Palazzi, Xavier, Chen, Joseph, Pithavala, Yazdi K, Finkelstein, Martin

“…Abstract Lorlatinib is a potent small-molecule anaplastic lymphoma kinase inhibitor approved for the treatment of patients with nonsmall cell lung cancer. In a…”
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Age‐ and sex‐related changes in body weights and clinical pathology analytes in cynomolgus monkeys (Macaca Fascicularis) of Mauritius origin by Li, Xiantang, Li, Dingzhou, Biddle, Kathleen E., Portugal, Susan S., Li, Mark R., Santos, Rosemary, Burkhardt, John E., Khan, Nasir K.

“…Background Clinical pathology and body weight information for the cynomolgus monkey in the literature is primarily derived from a small number of animals with…”
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Local and Systemic Changes Associated with Long-term, Percutaneous, Static Implantation of Titanium Alloys in Rhesus Macaques (Macaca mulatta) by Frydman, Galit H, Marini, Robert P, Bakthavatchalu, Vasudevan, Biddle, Kathleen E, Muthupalani, Sureshkumar, Vanderburg, Charles R, Lai, Barry, Bendapudi, Pavan K, Tompkins, Ronald G, Fox, James G

“…Metal alloys are frequently used as implant materials in veterinary medicine. Recent studies suggest that many alloys induce both local and systemic…”
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Selection of transgenic Xenopus laevis using antibiotic resistance by MORITZ, Orson L, BIDDLE, Kathleen E, TAM, Beatrice M

“…We previously established lines of transgenic Xenopus laevis expressing green fluorescent protein (GFP) or GFP fusion proteins in the rod photoreceptors of…”
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