Search Results - "Bicsak, T A"

Follistatin and activin: a potential intrinsic regulatory system within diverse tissues by DePaolo, L V, Bicsak, T A, Erickson, G F, Shimasaki, S, Ling, N

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Long-term effects of exenatide therapy over 82 weeks on glycaemic control and weight in over-weight metformin-treated patients with type 2 diabetes mellitus by Ratner, R. E., Maggs, D., Nielsen, L. L., Stonehouse, A. H., Poon, T., Zhang, B., Bicsak, T. A., Brodows, R. G., Kim, D. D.

“…Aim:  The ability of the incretin mimetic exenatide to improve glycaemic control and reduce body weight was assessed over 82 weeks in patients with type 2…”
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Insulin-like growth factor-binding protein (IGF-BP) inhibition of granulosa cell function: effect on cyclic adenosine 3',5'-monophosphate, deoxyribonucleic acid synthesis, and comparison with the effect of an IGF-I antibody by Bicsak, T A, Shimonaka, M, Malkowski, M, Ling, N

“…The effects of insulin-like growth factor binding proteins (IGF-BPs) purified from porcine follicular fluid on granulosa cell function were examined using…”
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Ovarian intrabursal administration of insulin-like growth factor-binding protein inhibits follicle rupture in gonadotropin-treated immature female rats by BICSAK, T. A, LING, N, DEPAOLO, L. V

“…The effects of an insulin-like growth factor-binding protein (IGF-BP) on rat follicular function were examined by using the technique of ovarian intrabursal…”
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Follistatin gene expression in the ovary and extragonadal tissues by Shimasaki, S, Koga, M, Buscaglia, M L, Simmons, D M, Bicsak, T A, Ling, N

“…Follistatin is a glycosylated single-chain protein originally isolated from porcine follicular fluid. It specifically inhibits the secretion of FSH from the…”
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Hormonal regulation of granulosa cell inhibin biosynthesis by Bicsak, T A, Tucker, E M, Cappel, S, Vaughan, J, Rivier, J, Vale, W, Hsueh, A J

“…The hormonal regulation of inhibin production by cultured granulosa cells from immature hypophysectomized, estrogen-treated rats was examined using a specific…”
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Hormonal regulation of inhibin production by cultured Sertoli cells by Bicsak, T A, Vale, W, Vaughan, J, Tucker, E M, Cappel, S, Hsueh, A J

“…The hormonal regulation of inhibin production by cultured rat Sertoli cells was examined using a specific radioimmunoassay (RIA) which detects the N-terminal…”
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Rat oocyte tissue plasminogen activator is a catalytically efficient enzyme in the absence of fibrin. Endogenous potentiation of enzyme activity by BICSAK, T. A, HSUEH, A. J. W

“…Rat oocytes synthesize tissue plasminogen activator (tPA) in response to stimuli which initiate meiotic maturation. Purified tPA exhibits optimal activity only…”
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Inhibin: studies of stored and secreted forms by biosynthetic labeling and immunodetection in cultured rat granulosa cells by Bicsak, T A, Cajander, S B, Vale, W, Hsueh, A J

“…The biosynthesis of inhibin in rat granulosa cells was studied by biosynthetic labeling, immunoblotting, and immunocytochemical techniques. Granulosa cells…”
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Novel ovarian regulatory peptides: inhibin, activin, and follistatin by Ling, N, DePaolo, L V, Bicsak, T A, Shimasaki, S

“…Based on the extensive amount of research on inhibin and related polypeptides accomplished during the past 5 years, the inhibin concept put forth more than 50…”
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Purification and characterization of tadpole back-skin collagenase with low gelatinase activity by Bicsak, T A, Harper, E

“…A collagenase secreted by tadpole (Rana catesbiana) back-skin explants in culture has been purified to electrophoretic homogeneity by successive chromatography…”
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Phorbol ester increases plasminogen activator inhibitor accumulation in cultures of human granulosa cells by Kessel, B, Bicsak, T A, Garzo, V G

“…Proteolytic enzymes such as plasminogen activators (PAs) and collagenases are implicated in the process of ovarian follicle rupture. Data obtained in rats…”
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Purification of nonspecific protease-free collagenase from Clostridium histolyticum by Bicsak, T A, Harper, E

“…The collagenase (EC 3.4.24.3) produced by the bacterium Clostridium histolyticum has been purified free from nonspecific protease contaminants by a two-step…”
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Tissue-type plasminogen activator in rat oocytes: expression during the periovulatory period, after fertilization, and during follicular atresia by Bicsak, T A, Cajander, S B, Peng, X R, Ny, T, LaPolt, P S, Lu, J K, Kristensen, P, Tsafriri, A, Hsueh, A J

“…The regulation of tissue-type plasminogen activator (tPA) in rat oocytes during the periovulatory period, in early embryos, and in oocytes during induced…”
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Rat granulosa cells produce a novel trypsin-like protease in response to gonadotropin treatment by Bicsak, T A, Michelson, D S, Hsueh, A J

“…Rat ovaries produce a novel ovarian trypsin-like protease that is regulated during follicular development. The protease extracted from the ovaries of immature…”
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Chemical and kinetic characterization of tadpole back skin collagenase by Bicsak, T A, Harper, E

“…The purified collagenase from tadpole (Rana catesbiana) back skin was studied with respect to its activation energy using soluble and fibrillar type I…”
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Suppression of ovulation rate by antibodies to tissue-type plasminogen activator and alpha 2-antiplasmin by Tsafriri, A, Bicsak, T A, Cajander, S B, Ny, T, Hsueh, A J

“…Indirect evidence has suggested a role for plasminogen activator (PA) in ovulation. Our recent studies demonstrated that 1) tissue-type PA (tPA) is the…”
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Naturally Occurring Antihormones: Secretion of FSH Antagonists by Women Treated with a GnRH Analog by Dahl, Kristine D., Bicsak, Thomas A., Aaron J. W. Hsueh

“…Follicle-stimulating hormone (FSH) is a glycoprotein essential for gonadal development and steroidogenesis. Recent studies suggest that deglycosylation of FSH…”
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Population control not the answer by Bicsak, Thomas A

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Synthetic Exendin-4 (Exenatide) Significantly Reduces Postprandial and Fasting Plasma Glucose in Subjects with Type 2 Diabetes by Kolterman, Orville G., Buse, John B., Fineman, Mark S., Gaines, Eling, Heintz, Sonja, Bicsak, Thomas A., Taylor, Kristin, Kim, Dennis, Aisporna, Maria, Wang, Yan, Baron, Alain D.

“…Despite the advent of new treatments, glucose control in the type 2 diabetes population is unsatisfactory. AC2993 (synthetic exendin-4; exenatide), a novel…”
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