Search Results - "Bicocca, Vincent T"

ASH1-catalyzed H3K36 methylation drives gene repression and marks H3K27me2/3-competent chromatin by Bicocca, Vincent T, Ormsby, Tereza, Adhvaryu, Keyur K, Honda, Shinji, Selker, Eric U

“…Methylation of histone H3 at lysine 36 (H3K36me), a widely-distributed chromatin mark, largely results from association of the lysine methyltransferase (KMT)…”
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Crosstalk between ROR1 and the Pre-B Cell Receptor Promotes Survival of t(1;19) Acute Lymphoblastic Leukemia by Bicocca, Vincent T., Chang, Bill H., Masouleh, Behzad Kharabi, Muschen, Markus, Loriaux, Marc M., Druker, Brian J., Tyner, Jeffrey W.

“…We report that t(1;19) ALL cells universally exhibit expression of and dependence on the cell surface receptor ROR1. We further identify t(1;19) ALL cell…”
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LSD1 prevents aberrant heterochromatin formation in Neurospora crassa by Storck, William K, Bicocca, Vincent T, Rountree, Michael R, Honda, Shinji, Ormsby, Tereza, Selker, Eric U

“…Abstract Heterochromatin is a specialized form of chromatin that restricts access to DNA and inhibits genetic processes, including transcription and…”
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Urinary comprehensive genomic profiling predicts urothelial carcinoma recurrence and identifies responders to intravesical therapy by Rac, Goran, Patel, Hiten D., James, Christopher, Desai, Shalin, Caruso, Vincent M., Fischer, Daniel S., Lentz, Peter S., Ward, Ceressa T., Mazzarella, Brian C., Phillips, Kevin G., Doshi, Chirag, Bicocca, Vincent T., Levin, Trevor G., Wolfe, Alan J., Gupta, Gopal N.

“…Intravesical therapy (IVT) is the standard of care to decrease risk of recurrence and progression for high‐grade nonmuscle‐invasive bladder cancer. However,…”
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A Light-Inducible Strain for Genome-Wide Histone Turnover Profiling in Neurospora crassa by Storck, William K, Abdulla, Sabrina Z, Rountree, Michael R, Bicocca, Vincent T, Selker, Eric U

“…Abstract In chromatin, nucleosomes are composed of ∼146 bp of DNA wrapped around a histone octamer, and are highly dynamic structures subject to remodeling and…”
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Development and multicenter case-control validation of urinary comprehensive genomic profiling for urothelial carcinoma diagnosis, surveillance, and risk prediction by Salari, Keyan, Sundi, Debasish, Lee, Jason J, Wu, Shulin, Wu, Chin-Lee, DiFiore, Gabrielle, Yan, Q Robert, Pienkny, Andrew, Lee, Chi K, Oberlin, Daniel, Barme, Greg, Piser, Joel, Kahn, Robert, Collins, Edward, Phillips, Kevin G, Caruso, Vincent M, Goudarzi, Mahdi, Garcia-Ransom, Monica, Lentz, Peter S, Evans-Holm, Martha E, MacBride, Andrew R, Fischer, Daniel S, Haddadzadeh, Iden J, Mazzarella, Brian C, Gray, Joe W, Koppie, Theresa M, Bicocca, Vincent T, Levin, Trevor G, Lotan, Yair, Feldman, Adam S

“…Urinary comprehensive genomic profiling (uCGP) uses next-generation sequencing to identify mutations associated with urothelial carcinoma (UC) and has the…”
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Maintenance and pharmacologic targeting of ROR1 protein levels via UHRF1 in t(1;19) pre-B-ALL by Chow, Marilynn, Gao, Lina, MacManiman, Jason D., Bicocca, Vincent T., Chang, Bill H., Alumkal, Joshi J., Tyner, Jeffrey W.

“…Expression of the transmembrane pseudokinase ROR1 is required for survival of t(1;19)-pre-B-cell acute lymphoblastic leukemia (t(1;19) pre-B-ALL), chronic…”
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Dual chromatin recognition by the histone deacetylase complex HCHC is required for proper DNA methylation in Neurospora crassa by Honda, Shinji, Bicocca, Vincent T., Gessaman, Jordan D., Rountree, Michael R., Yokoyama, Ayumi, Yu, Eun Y., Selker, Jeanne M. L., Selker, Eric U.

“…DNA methylation, heterochromatin protein 1 (HP1), histone H3 lysine 9 (H3K9) methylation, histone deacetylation, and highly repeated sequences are prototypical…”
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Minimal Residual Disease Detection with Urine-derived DNA Is Prognostic for Recurrence-free Survival in Bacillus Calmette-Guérin–unresponsive Non–muscle-invasive Bladder Cancer Treated with Nadofaragene Firadenovec by Narayan, Vikram M., Tholomier, Come, Mokkapati, Sharada, Martini, Alberto, Caruso, Vincent M., Goudarzi, Mahdi, Mazzarella, Brian C., Phillips, Kevin G., Bicocca, Vincent T., Levin, Trevor G., Yla-Herttuala, Seppo, McConkey, David J., Dinney, Colin P.N.

“…In patients with bacillus Calmette-Guérin–unresponsive non–muscle-invasive bladder cancer, urine DNA profiling identifies those with the greatest likelihood of…”
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Urinary Comprehensive Genomic Profiling Correlates Urothelial Carcinoma Mutations with Clinical Risk and Efficacy of Intervention by Bicocca, Vincent T., Phillips, Kevin G., Fischer, Daniel S., Caruso, Vincent M., Goudarzi, Mahdi, Garcia-Ransom, Monica, Lentz, Peter S., MacBride, Andrew R., Jensen, Brad W., Mazzarella, Brian C., Koppie, Theresa, Korkola, James E., Gray, Joe W., Levin, Trevor G.

“…The clinical standard of care for urothelial carcinoma (UC) relies on invasive procedures with suboptimal performance. To enhance UC treatment, we developed a…”
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Clinical utility of urinary comprehensive genomic profiling in diagnosing metachronous upper tract urothelial carcinoma: a case report by Yonover, Paul M., Ward, Ceressa T., Mazzarella, Brian C., Phillips, Kevin G., Jensen, Brad W., Bicocca, Vincent T., Duffy, Kathleen, Yonover, Jaden, Cherry, Ava, Levin, Trevor G.

“…Introduction and aim of study Metachronous upper tract urothelial carcinoma (UTUC) is a rare yet aggressive malignancy that is often multifocal and invasive at…”
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ROR1 Flow Cytometry by Vincent Bicocca, Jeffrey Tyner

“…ROR1 is a receptor tyrosine kinase family member studied for its roles in development and cancer. Here we describe a protocol for analysis of ROR1 surface…”
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Immunoprecipitation of ROR1 by Vincent Bicocca, Jeffrey Tyner

“…ROR1 is a receptor tyrosine kinase family member studied for its roles in development and cancer. Here we describe a protocol for immunoprecipitation of…”
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PD41-03 URINARY COMPREHENSIVE GENOMIC PROFILING ASSISTS IN NON-INVASIVE DETECTION AND MOLECULAR STAGING OF UPPER TRACT UROTHELIAL CARCINOMA by Brönimann, Stephan, Pallauf, Maximilian, Fischer, Daniel S., Hamlington, Barbara, Bicocca, Vincent T., Levin, Trevor G., McConkey, David J., Singla, Nirmish

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MP16-07 URINARY MINIMAL RESIDUAL DISEASE DETECTION PREDICTS RECURRENCE IN BCG-UNRESPONSIVE NIMBC AND QUANTIFIES MOLECULAR RESPONSE TO NADOFARAGENE FIRADENOVEC by Narayan, Vikram M., Tholomier, Come, Mokkapati, Sharada, Martini, Alberto, Caruso, Vincent M., Mazzarella, Brian C., Phillips, Kevin G., Bicocca, Vincent T., Levin, Trevor G., Sawutz, David, Yla-Herttuala, Seppo, Parker, Nigel, McConkey, David J., Dinney, Colin P. N.

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Urinary minimal residual disease detection predicts recurrence in BCG-unresponsive NIMBC and quantifies molecular response to nadofaragene firadenovec by Narayan, Vikram M, Tholomier, Come, Mokkapati, Sharada, Martini, Alberto, Caruso, Vincent M., Mazzarella, Brian C., Phillips, Kevin G., Bicocca, Vincent T., Levin, Trevor G., Yla-Herttuala, Seppo, Sawutz, David, Parker, Nigel, McConkey, David James, Dinney, Colin P.N.

“…635 Background: Urinary minimal residual disease (uMRD) profiling uses next-generation sequencing to identify mutations associated with urothelial carcinoma…”
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Comprehensive genomic profiling of urine DNA for urothelial carcinoma detection and risk prediction by Salari, Keyan, Lee, Jason J., Bicocca, Vincent T., Caruso, Vincent, Mazzarella, Brian C., Phillips, Kevin G., Levin, Trevor G., Feldman, Adam S.

“…Abstract only 450 Background: Clinical diagnosis and risk stratification of patients with urothelial carcinoma (UC) remains a challenge, with high rates of…”
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PD46-07 URINARY COMPREHENSIVE GENOMIC PROFILING AIDS IN DETECTION AND RISK PROGNOSIS OF UPPER TRACT UROTHELIAL CARCINOMA: A CASE-CONTROLLED COHORT STUDY by Yonover, Paul, Kaplinsky, Robert, Salari, Keyan, Feldman, Adam, Sundi, Debasish, Phillips, Kevin G., Fisher, Daniel, Cherry, Ava, Mazzarella, Brian C., Bicocca, Vincent T., Gray, Joe, Koppie, Theresa M., Levin, Trevor G., Cohen, Justin

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Correlation of urinary comprehensive genomic profile with risk of recurrence of BCG-unresponsive non-muscle invasive bladder cancer treated with atezolizumab in SWOG S1605 by St-Laurent, Marie-Pier, Plets, Melissa, Black, Peter C., Singh, Parminder, McConkey, David James, Lucia, Scott, Koshkin, Vadim S, Stratton, Kelly Lynn, Bivalacqua, Trinity, Kassouf, Wassim, Porten, Sima P., Bangs, Rick, Tangen, Catherine, Thompson, Ian M., Meeks, Joshua J, Caruso, Vincent M., Phillips, Kevin G., Bicocca, Vincent T., Levin, Trevor G., Lerner, Seth P.

“…529 Background: Radical cystectomy is recommended for patients with BCG-unresponsive (BU) non-muscle invasive bladder cancer (NMIBC) due to high risk of…”
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MP22-19 URINARY COMPREHENSIVE GENOMIC PROFILING PREDICTS UROTHELIAL CANCER UP TO 12 YEARS AHEAD OF CLINICAL DIAGNOSIS. AN EXPANDED ANALYSIS OF THE GOLESTAN COHORT STUDY by Lotan, Yair, Salari, Keyan, Feldman, Adam, Sundi, Debasish, Lee, Jason J, DiFiore, Gabrielle, Poustchi, Hossein, Khoshnia, Masoud, Roshandel, Gholamreza, Etemadi, Arash, Goudarzi, Mahdi, Lentz, Peter S., Phillips, Kevin G., Bicocca, Vincent T., Koppie, Theresa M., Gray, Joe W., Levin, Trevor, Malekzadeh, Reza, Sheikh, Mahdi, Le Calvez-Kelm, Florence

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