Search Results - "Bickel, Marisa A"
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Cell non-autonomous regulation of cerebrovascular aging processes by the somatotropic axis
Published in Frontiers in endocrinology (Lausanne) (23-01-2023)“…Age-related cerebrovascular pathologies, ranging from cerebromicrovascular functional and structural alterations to large vessel atherosclerosis, promote the…”
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The effects of time restricted feeding on age-related changes in the mouse retina
Published in Experimental gerontology (01-09-2024)“…Dietary modifications such as caloric restriction (CR) and intermittent fasting (IF) have gained popularity due to their proven health benefits in aged…”
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Increased Susceptibility to Cerebral Microhemorrhages Is Associated With Imaging Signs of Microvascular Degeneration in the Retina in an Insulin-Like Growth Factor 1 Deficient Mouse Model of Accelerated Aging
Published in Frontiers in aging neuroscience (09-03-2022)“…Age-related cerebrovascular defects contribute to vascular cognitive impairment and dementia (VCID) as well as other forms of dementia. There has been great…”
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IGF1R deficiency in vascular smooth muscle cells impairs myogenic autoregulation and cognition in mice
Published in Frontiers in aging neuroscience (15-02-2024)“…Cerebrovascular pathologies contribute to cognitive decline during aging, leading to vascular cognitive impairment and dementia (VCID). Levels of circulating…”
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Microvascular smooth muscle cells exhibit divergent phenotypic switching responses to platelet-derived growth factor and insulin-like growth factor 1
Published in Microvascular research (01-01-2024)“…Vascular smooth muscle cell (VSMC) phenotypic switching is critical for normal vessel formation, vascular stability, and healthy brain aging. Phenotypic…”
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A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice
Published in Journal of the American Society of Nephrology (01-04-2022)“…Inducible disruption of cilia-related genes in adult mice results in slowly progressive cystic disease, which can be greatly accelerated by renal injury. To…”
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Vascular smooth muscle cell-specific Igf1r deficiency exacerbates the development of hypertension-induced cerebral microhemorrhages and gait defects
Published in GeroScience (01-06-2024)“…Cerebrovascular fragility and cerebral microhemorrhages (CMH) contribute to age-related cognitive impairment, mobility defects, and vascular cognitive…”
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