Search Results - "Bichakjian, Christopher K"

Analysis of Prognostic Factors from 9387 Merkel Cell Carcinoma Cases Forms the Basis for the New 8th Edition AJCC Staging System by Harms, Kelly L., Healy, Mark A., Nghiem, Paul, Sober, Arthur J., Johnson, Timothy M., Bichakjian, Christopher K., Wong, Sandra L.

“…Background The first consensus Merkel cell carcinoma (MCC) staging system was published in 2010. New information on the clinical course prompts review of MCC…”
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Guidelines of care for the management of primary cutaneous melanoma by Swetter, Susan M., Tsao, Hensin, Bichakjian, Christopher K., Curiel-Lewandrowski, Clara, Elder, David E., Gershenwald, Jeffrey E., Guild, Valerie, Grant-Kels, Jane M., Halpern, Allan C., Johnson, Timothy M., Sober, Arthur J., Thompson, John A., Wisco, Oliver J., Wyatt, Samantha, Hu, Shasa, Lamina, Toyin

“…The incidence of primary cutaneous melanoma continues to increase each year. Melanoma accounts for the majority of skin cancer–related deaths, but treatment is…”
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Basal Cell Carcinoma Preferentially Arises from Stem Cells within Hair Follicle and Mechanosensory Niches by Peterson, Shelby C., Eberl, Markus, Vagnozzi, Alicia N., Belkadi, Abdelmadjid, Veniaminova, Natalia A., Verhaegen, Monique E., Bichakjian, Christopher K., Ward, Nicole L., Dlugosz, Andrzej A., Wong, Sunny Y.

“…Basal cell carcinoma (BCC) is characterized by frequent loss of PTCH1, leading to constitutive activation of the Hedgehog pathway. Although the requirement for…”
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Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis by Reiter, Jeremy F, Wong, Sunny Y, Seol, Allen D, So, Po-Lin, Ermilov, Alexandre N, Bichakjian, Christopher K, Epstein, Ervin H, Dlugosz, Andrzej A

“…Primary cilia are present on most mammalian cells and are implicated in transducing Hedgehog (Hh) signals during development; however, the prevalence of cilia…”
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Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC by Becker, Jürgen C., Stang, Andreas, Hausen, Axel zur, Fischer, Nicole, DeCaprio, James A., Tothill, Richard W., Lyngaa, Rikke, Hansen, Ulla Kring, Ritter, Cathrin, Nghiem, Paul, Bichakjian, Christopher K., Ugurel, Selma, Schrama, David

“…Merkel cell carcinoma (MCC) is a highly aggressive, often lethal neuroendocrine cancer. Its carcinogenesis may be either caused by the clonal integration of…”
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Guidelines of care for the management of primary cutaneous melanoma by Bichakjian, Christopher K., MD, Halpern, Allan C., MD (Co-chair), Johnson, Timothy M., MD (Co-chair), Foote Hood, Antoinette, MD, Grichnik, James M., MD, PhD, Swetter, Susan M., MD, Tsao, Hensin, MD, PhD, Barbosa, Victoria Holloway, MD, Chuang, Tsu-Yi, MD, MPH, Duvic, Madeleine, MD, Ho, Vincent C., MD, Sober, Arthur J., MD, Beutner, Karl R., MD, PhD, Bhushan, Reva, PhD, Smith Begolka, Wendy, MS

“…The incidence of primary cutaneous melanoma has been increasing dramatically for several decades. Melanoma accounts for the majority of skin cancer–related…”
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Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: Analysis of 5823 cases as the basis of the first consensus staging system by Lemos, Bianca D., MD, Storer, Barry E., PhD, Iyer, Jayasri G., MD, Phillips, Jerri Linn, MA, CTR, Bichakjian, Christopher K., MD, Fang, L. Christine, MD, Johnson, Timothy M., MD, Liegeois-Kwon, Nanette J., MD, PhD, Otley, Clark C., MD, Paulson, Kelly G., PhD, Ross, Merrick I., MD, Yu, Siegrid S., MD, Zeitouni, Nathalie C., MD, Byrd, David R., MD, Sondak, Vernon K., MD, Gershenwald, Jeffrey E., MD, Sober, Arthur J., MD, Nghiem, Paul, MD, PhD

“…Background The management of Merkel cell carcinoma (MCC) has been complicated by a lack of detailed prognostic data and by the presence of conflicting staging…”
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Relationships among primary tumor size, number of involved nodes, and survival for 8044 cases of Merkel cell carcinoma by Iyer, Jayasri G., MD, Storer, Barry E., PhD, Paulson, Kelly G., MD, PhD, Lemos, Bianca, MD, Phillips, Jerri Linn, MA, CTR, Bichakjian, Christopher K., MD, Zeitouni, Nathalie, MD, Gershenwald, Jeffrey E., MD, Sondak, Vernon, MD, Otley, Clark C., MD, Yu, Siegrid S., MD, Johnson, Timothy M., MD, Liegeois, Nanette J., MD, Byrd, David, MD, Sober, Arthur, MD, Nghiem, Paul, MD, PhD

“…Background The effects of primary tumor size on nodal involvement and of number of involved nodes on survival have not, to our knowledge, been examined in a…”
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Features Predicting Sentinel Lymph Node Positivity in Merkel Cell Carcinoma by SCHWARTZ, Jennifer L, GRIFFITH, Kent A, JOHNSON, Timothy M, BICHAKJIAN, Christopher K, LOWE, Lori, WONG, Sandra L, MCLEAN, Scott A, FULLEN, Douglas R, LAO, Christopher D, HAYMAN, James A, BRADFORD, Carol R, REES, Riley S

“…Merkel cell carcinoma (MCC) is a relatively rare, potentially aggressive cutaneous malignancy. We examined the clinical and histologic features of primary MCC…”
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Distinct Gene Expression Profiles of Viral- and Nonviral-Associated Merkel Cell Carcinoma Revealed by Transcriptome Analysis by Harms, Paul W., Patel, Rajiv M., Verhaegen, Monique E., Giordano, Thomas J., Nash, Kevin T., Johnson, Craig N., Daignault, Stephanie, Thomas, Dafydd G., Gudjonsson, Johann E., Elder, James T., Dlugosz, Andrzej A., Johnson, Timothy M., Fullen, Douglas R., Bichakjian, Christopher K.

“…Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumor with high mortality rates. Merkel cell polyomavirus (MCPyV), identified in the…”
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Management of Early-Stage Melanoma by Quintanilla-Dieck, Maria J., MD, Bichakjian, Christopher K., MD

“…Melanoma is a potentially aggressive skin cancer with a steadily rising incidence. Most melanomas are diagnosed at an early stage and associated with an…”
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Update on Keratinocyte Carcinomas by Nehal, Kishwer S, Bichakjian, Christopher K

“…Squamous-cell and basal-cell carcinomas of the skin are increasing in frequency. Basal-cell carcinomas are responsive to inhibition of the hedgehog pathway;…”
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Dermatofibrosarcoma Protuberans: How Wide Should We Resect? by Farma, Jeffrey M., Ammori, John B., Zager, Jonathan S., Marzban, Suroosh S., Bui, Marilyn M., Bichakjian, Christopher K., Johnson, Timothy M., Lowe, Lori, Sabel, Michael S., Wong, Sandra L., Douglas Letson, G., Messina, Jane L., Cimmino, Vincent M., Sondak, Vernon K.

“…Background Dermatofibrosarcoma protuberans (DFSP) is a rare dermal tumor with local recurrence rates ranging from 0 to 50%. Controversy exists regarding margin…”
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Dermatoscopic vascular patterns in cutaneous Merkel cell carcinoma by Harting, Mandy S., MD, Ludgate, Mathew W., MBChB, FRACP, Fullen, Douglas R., MD, Johnson, Timothy M., MD, Bichakjian, Christopher K., MD

“…Background Merkel cell carcinoma (MCC) is one of the most aggressive primary cutaneous malignancies. The clinical diagnosis of MCC is often delayed. Although…”
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Small cell carcinoma in the parotid harboring Merkel cell polyomavirus by Fisher, Clayton A., DDS, Harms, Paul W., MD, PhD, McHugh, Jonathan B., MD, Edwards, Paul C., DDS, MSc, Siddiqui, Javed, MS, Palanisamy, Nallasivam, PhD, Bichakjian, Christopher K., MD, Benavides, Erika, DDS, PhD, Danciu, Theodora E., DMD, DMSc

“…Objective This study aimed to document three new cases of primary small cell carcinoma (SmCC) of the parotid and examine immunohistochemical and quantitative…”
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Clinicopathologic Features of Primary Merkel Cell Carcinoma: A Detailed Descriptive Analysis of a Large Contemporary Cohort by Schwartz, Jennifer L., Bichakjian, Christopher K., Lowe, Lori, Griffith, Kent A., Frohm, Marcus L., Fullen, Douglas R., Hayman, James A., Lao, Christopher D., Shah, Khooshbu S., McLean, Scott A., Bradford, Carol R., Johnson, Timothy M., Wong, Sandra L.

“…Background Little uniformity exists in the clinical and histologic variables reported with primary Merkel cell carcinoma (MCC). Objective To provide a rigorous…”
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Merkel Cell Carcinoma Therapeutic Update by Cassler, Nicole M., Merrill, Dean, Bichakjian, Christopher K., Brownell, Isaac

“…Opinion statement Merkel cell carcinoma (MCC) is a rare and aggressive neuroendocrine tumor of the skin. Early-stage disease can be cured with surgical…”
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Reply to: “Comment on ‘Guidelines of care for the management of basal cell carcinoma’” by Bichakjian, Christopher K., Alam, Murad

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Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice by Verhaegen, Monique E, Mangelberger, Doris, Harms, Paul W, Eberl, Markus, Wilbert, Dawn M, Meireles, Julia, Bichakjian, Christopher K, Saunders, Thomas L, Wong, Sunny Y, Dlugosz, Andrzej A

“…Merkel cell carcinoma (MCC) tumor cells express several markers detected in normal Merkel cells, a nonproliferative population of neuroendocrine cells that…”
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Virus-positive Merkel Cell Carcinoma Is an Independent Prognostic Group with Distinct Predictive Biomarkers by Harms, Kelly L, Zhao, Lili, Johnson, Bryan, Wang, Xiaoming, Carskadon, Shannon, Palanisamy, Nallasivam, Rhodes, Daniel R, Mannan, Rahul, Vo, Josh N, Choi, Jae Eun, Chan, May P, Fullen, Douglas R, Patel, Rajiv M, Siddiqui, Javed, Ma, Vincent T, Hrycaj, Steven, McLean, Scott A, Hughes, Tasha M, Bichakjian, Christopher K, Tomlins, Scott A, Harms, Paul W

“…Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma that can be divided into two classes: virus-positive (VP) MCC, associated with…”
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