Search Results - "Biburger, Markus"

My Name Is Legion, for We Are Many—The Complex Community of Antibody Receptors by Biburger, Markus

“…Antibodies act as the central mediators of immunological defense mechanisms, therapeutic agents within clinics, and the mediators of various immune-mediated…”
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There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes by Kerntke, Christina, Nimmerjahn, Falk, Biburger, Markus

“…Antibodies are essential mediators of immunological defense mechanisms, are clinically used as therapeutic agents, but are also functionally involved in…”
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There Is Strength in Numbers: Quantitation of Fc Gamma Receptors on Murine Tissue-Resident Macrophages by Vorsatz, Christof, Friedrich, Niklas, Nimmerjahn, Falk, Biburger, Markus

“…Many of the effector functions of antibodies rely on the binding of antibodies/immune complexes to cellular Fcγ receptors (FcγRs). Since the majority of innate…”
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Corrigendum: There Is (Scientific) Strength in Numbers: A Comprehensive Quantitation of Fc Gamma Receptor Numbers on Human and Murine Peripheral Blood Leukocytes by Kerntke, Christina, Nimmerjahn, Falk, Biburger, Markus

“…[This corrects the article DOI: 10.3389/fimmu.2020.00118.]…”
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IVIg‐mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1 by Schwab, Inessa, Biburger, Markus, Krönke, Gerhard, Schett, Georg, Nimmerjahn, Falk

“…Intravenous immunoglobulin G (IVIg) therapy is widely used to treat autoimmune and inflammatory diseases. Recent evidence suggests that in mice, splenic…”
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Mixed IgG Fc immune complexes exhibit blended binding profiles and refine FcR affinity estimates by Tan, Zhixin Cyrillus, Lux, Anja, Biburger, Markus, Varghese, Prabha, Lees, Stephen, Nimmerjahn, Falk, Meyer, Aaron S.

“…Immunoglobulin G (IgG) antibodies coordinate immune effector responses by interacting with effector cells via fragment crystallizable γ (Fcγ) receptors. The…”
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Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease by Uderhardt, Stefan, Ackermann, Jochen A, Fillep, Tobias, Hammond, Victoria J, Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R, Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Dietel, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W, Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L, Lee, James J, Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B, Krönke, Gerhard

“…Blood coagulation is essential for physiological hemostasis but simultaneously contributes to thrombotic disease. However, molecular and cellular events…”
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The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity by Gordan, Sina, Albert, Heike, Danzer, Heike, Lux, Anja, Biburger, Markus, Nimmerjahn, Falk

“…Cytotoxic immunoglobulin G antibodies are an essential component of therapeutic approaches aimed at depleting self-reactive or malignant cells. More recent…”
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Tissue niche occupancy determines the contribution of fetal- versus bone-marrow-derived macrophages to IgG effector functions by Wöhner, Miriam, Brechtelsbauer, Sarah, Friedrich, Niklas, Vorsatz, Christof, Bulang, Johanna, Liang, Chunguang, Schorr, Lena, Beschin, Alain, Guilliams, Martin, Ravetch, Jeffrey, Nimmerjahn, Falk, Biburger, Markus

“…Understanding the mechanisms underlying cytotoxic immunoglobulin G (IgG) activity is critical for improving therapeutic antibody activity and inhibiting…”
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Mechanisms of action of intravenous immunoglobulins by Baerenwaldt, Anne, Biburger, Markus, Nimmerjahn, Falk

“…Intravenous immunoglobulin (IVIg) has been used for nearly three decades as an efficient anti-inflammatory therapeutic regimen in a growing number of…”
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IMy Name Is Legion, for We Are Many/I—The Complex Community of Antibody Receptors by Biburger, Markus

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Pivotal Advance: Heme oxygenase 1 expression by human CD4+ T cells is not sufficient for their development of immunoregulatory capacity by Markus Biburger, Gabi Theiner, Mirjam Schädle, Gerold Schuler, Gisa Tiegs

“…HO‐1 induction in human T cells inhibits their proliferation, HO‐1 suppression in Tregs increases their proliferation, but neither treatment fundamentally…”
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Correction: Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease by Uderhardt, Stefan, Ackermann, Jochen A, Fillep, Tobias, Hammond, Victoria J, Willeit, Johann, Santer, Peter, Mayr, Manuel, Biburger, Markus, Miller, Meike, Zellner, Katie R, Stark, Konstantin, Zarbock, Alexander, Rossaint, Jan, Schubert, Irene, Mielenz, Dirk, Dietel, Barbara, Raaz-Schrauder, Dorette, Ay, Cihan, Gremmel, Thomas, Thaler, Johannes, Heim, Christian, Herrmann, Martin, Collins, Peter W, Schabbauer, Gernot, Mackman, Nigel, Voehringer, David, Nadler, Jerry L, Lee, James J, Massberg, Steffen, Rauh, Manfred, Kiechl, Stefan, Schett, Georg, O'Donnell, Valerie B, Krönke, Gerhard

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Activation-induced NKT cell hyporesponsiveness protects from α-galactosylceramide hepatitis and is independent of active transregulatory factors by Biburger, Markus, Tiegs, Gisa

“…NK T (NKT) cells, unique lymphocytes expressing features of NK and T lymphocytes, can specifically be activated with the glycolipid antigen…”
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bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression by Gordan, Sina, Biburger, Markus, Nimmerjahn, Falk

“…Summary The mononuclear phagocytic system consists of a great variety of cell subsets localized throughout the body in immunological and non‐immunological…”
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Three blocks are not enough—Blocking of the murine IgG receptor FcγRIV is crucial for proper characterization of cells by FACS analysis by Biburger, Markus, Trenkwald, Ines, Nimmerjahn, Falk

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IL‐10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A–induced liver injury in mice by Erhardt, Annette, Biburger, Markus, Papadopoulos, Thomas, Tiegs, Gisa

“…The liver appears to play an important role in immunological tolerance, for example, during allo‐transplantation. We investigated tolerance mechanisms in the…”
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How immunoglobulin G antibodies kill target cells: revisiting an old paradigm by Biburger, Markus, Lux, Anja, Nimmerjahn, Falk

“…The capacity of immunoglobulin G (IgG) antibodies to eliminate virtually any target cell has resulted in the widespread introduction of cytotoxic antibodies…”
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Low level of FcγRIII expression on murine natural killer cells by Biburger, Markus, Nimmerjahn, Falk

“…Highlights ► Fc-mediated binding of antibodies to murine FcγRIV causes flow cytometric artifacts. ► These artifacts can be avoided by blockade of FcγRIV. ►…”
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Construction and Characterization of Bispecific Costimulatory Molecules Containing a Minimized CD86 (B7-2) Domain and Single-Chain Antibody Fragments for Tumor Targeting by ROHRBACH, Florian, GERSTMAYER, Bernhard, BIBURGER, Markus, WELS, Winfried

“…Efficient T-cell activation requires two signals. The first signal, which confers specificity, is provided by interaction of the T-cell receptor with peptides…”
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