Search Results - "Bibl, M."

Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study by Lewczuk, P, Kamrowski-Kruck, H, Peters, O, Heuser, I, Jessen, F, Popp, J, Bürger, K, Hampel, H, Frölich, L, Wolf, S, Prinz, B, Jahn, H, Luckhaus, Ch, Perneczky, R, Hüll, M, Schröder, J, Kessler, H, Pantel, J, Gertz, H-J, Klafki, H-W, Kölsch, H, Reulbach, U, Esselmann, H, Maler, J M, Bibl, M, Kornhuber, J, Wiltfang, J

“…In this report, we present the results of a multicenter study to test analytic and diagnostic performance of soluble forms of amyloid precursor proteins α and…”
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Amyloid β peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing by Lewczuk, P., Kornhuber, J., Vanmechelen, E., Peters, O., Heuser, I., Maier, W., Jessen, F., Bürger, K., Hampel, H., Frölich, L., Henn, F., Falkai, P., Rüther, E., Jahn, H., Luckhaus, Ch, Perneczky, R., Schmidtke, K., Schröder, J., Kessler, H., Pantel, J., Gertz, H.-J., Vanderstichele, H., de Meyer, G., Shapiro, F., Wolf, S., Bibl, M., Wiltfang, J.

“…We measured concentrations of Aβ peptides 1–42 and 1–40, and their ratio in plasma of patients carefully categorized clinically and neurochemically as having…”
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Validation of amyloid-β peptides in CSF diagnosis of neurodegenerative dementias by BIBL, M, MOLLENHAUER, B, WILTFANG, J, LEWCZUK, P, ESSELMANN, H, WOLF, S, TRENKWALDER, C, OTTO, M, STIENS, G, RÜTHER, E, KORNHUBER, J

“…Biomarkers for differential diagnosis of the three most frequent degenerative forms of dementia, Alzheimer's disease (AD), dementia with Lewy bodies (DLB) and…”
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Highly conserved and disease‐specific patterns of carboxyterminally truncated Aβ peptides 1–37/38/39 in addition to 1–40/42 in Alzheimer's disease and in patients with chronic neuroinflammation by Wiltfang, J., Esselmann, H., Bibl, M., Smirnov, A., Otto, M., Paul, S., Schmidt, B., Klafki, H.‐W., Maler, M., Dyrks, T., Bienert, M., Beyermann, M., Rüther, E., Kornhuber, J.

“…Human lumbar CSF patterns of Aβ peptides were analysed by urea‐based β‐amyloid sodium dodecyl sulphate polyacrylamide gel electrophoresis with western…”
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Reduced CSF carboxyterminally truncated Aβ peptides in frontotemporal lobe degenerations by Bibl, M., Mollenhauer, B., Wolf, S., Esselmann, H., Lewczuk, P., Kornhuber, J., Wiltfang, J.

“…Cerebrospinal fluid (CSF) carboxyterminally truncated amyloid-beta (A beta ) peptides, A beta 1-42 and tau protein were evaluated in 30 patients with…”
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Tauopathies and synucleinopathies: do cerebrospinal fluid beta-amyloid peptides reflect disease-specific pathogenesis? by Mollenhauer, B, Bibl, M, Esselmann, H, Steinacker, P, Trenkwalder, C, Wiltfang, J, Otto, M

“…To evaluate variations in amyloid beta (Abeta) peptide pattern in cerebrospinal fluid (CSF) in neurodegenerative disorders. A recently established quantitative…”
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CSF diagnosis of Alzheimer's disease and dementia with Lewy bodies by Bibl, M, Mollenhauer, B, Esselmann, H, Lewczuk, P, Trenkwalder, C, Brechlin, P, Rüther, E, Kornhuber, J, Otto, M, Wiltfang, J

“…Differential diagnosis of Alzheimer's disease (AD) and dementia with Lewy bodies (DLB) is often crucial. CSF Tau protein and Amyloid-beta (A beta) peptides…”
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Aminoterminally truncated and oxidized amyloid-beta peptide species in Alzheimer’s disease by Bibl, M, Esselmann, H, Mollenhauer, B, Wiltfang, J

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Follow-up investigations in cerebrospinal fluid of patients with dementia with Lewy bodies and Alzheimer's disease by Mollenhauer, B, Bibl, M, Trenkwalder, C, Stiens, G, Cepek, L, Steinacker, P, Ciesielczyk, B, Neubert, K, Wiltfang, J, Kretzschmar, H A, Poser, S, Otto, M

“…Measuring proteins in cerebrospinal fluid (CSF) has gained wide acceptance for the differential diagnosis of dementia. Some groups have already extended these…”
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New perspectives in the laboratory diagnosis of dementia by Bibl, M, Wiltfang, J

“…Over the past 10 years, the status of laboratory analysis in dementia has increasingly changed from its use for exclusion diagnoses for secondary causes of…”
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Selective reduction of amyloid beta 42 discriminates Alzheimer's disease from Huntington's disease: indication for distinct pathological events in amyloid beta peptide aggregation by Mollenhauer, B, Bibl, M, Esselmann, H, Steinacker, P, Trenkwalder, C, Brechlin, P, Wiltfang, J, Otto, M

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Selective reduction of amyloid β42 discriminates Alzheimer’s disease from Huntington’s disease: indication for distinct pathological events in amyloid β peptide aggregation by Mollenhauer, B, Bibl, M, Esselmann, H, Steinacker, P, Trenkwalder, C, Brechlin, P, Wiltfang, J, Otto, M

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Stability of amyloid-β peptides in plasma and serum by Bibl, Mirko, Welge, Volker, Esselmann, Hermann, Wiltfang, Jens

“…Plasma amyloid‐β peptide (Aβ) levels have been suggested as a biomarker candidate for detecting incipient AD. Aβ peptides are known to be sensitive to distinct…”
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CSF amyloid-β-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia by Bibl, Mirko, Mollenhauer, Brit, Esselmann, Hermann, Lewczuk, Piotr, Klafki, Hans-Wolfgang, Sparbier, Katrin, Smirnov, Alexandr, Cepek, Lukas, Trenkwalder, Claudia, Rüther, Eckart, Kornhuber, Johannes, Otto, Markus, Wiltfang, Jens

“…As the differential diagnosis of dementias based on established clinical criteria is often difficult, biomarkers for applicable diagnostic testing are…”
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Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid beta peptides by Lewczuk, Piotr, Beck, Georg, Esselmann, Hermann, Bruckmoser, Ralf, Zimmermann, Rüdiger, Fiszer, Magdalena, Bibl, Mirko, Maler, Juan Manuel, Kornhuber, Johannes, Wiltfang, Jens

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Cerebrospinal fluid amyloid β peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: Indication of carrier-mediated epitope masking of amyloid β peptides by Bibl, Mirko, Esselmann, Hermann, Otto, Markus, Lewczuk, Piotr, Cepek, Lukas, Rüther, Eckart, Kornhuber, Johannes, Wiltfang, Jens

“…A quantitative urea‐based amyloid β (Aβ)‐sodium dodecyl sulfate‐polyacrylamide gel electrophoresis with Western immunoblot (Aβ‐SDS‐PAGE/immunoblot) reveals…”
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Characterization of cerebrospinal fluid aminoterminally truncated and oxidized amyloid-β peptides by Bibl, Mirko, Gallus, Marion, Welge, Volker, Lehmann, Sabine, Sparbier, Katrin, Esselmann, Hermann, Wiltfang, Jens

“…Purpose Carboxyterminally elongated and aminoterminally truncated Aβ peptides as well as their pyroglutamate and oxidized derivates are major constituents of…”
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Amyloid β peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease by Lewczuk, Piotr, Esselmann, Hermann, Groemer, Teja Wolfgang, Bibl, Mirko, Maler, Juan Manuel, Steinacker, Petra, Otto, Markus, Kornhuber, Johannes, Wiltfang, Jens

“…The advent of new therapeutic avenues for Alzheimer's disease (AD) calls for an improved early and differential diagnosis. With surface enhanced laser…”
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Total tau protein, phosphorylated tau (181p) protein, beta-amyloid(1-42), and beta-amyloid(1-40) in cerebrospinal fluid of patients with dementia with Lewy bodies by Mollenhauer, Brit, Bibl, Mirko, Wiltfang, Jens, Steinacker, Petra, Ciesielczyk, Barbara, Neubert, Karin, Trenkwalder, Claudia, Otto, Markus

“…The intra vitam diagnosis of different dementias is still based on clinical grounds. So far, no technical investigations have been available to support these…”
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Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer's disease: original data and review of the literature by Lewczuk, Piotr, Esselmann, Hermann, Bibl, Mirko, Beck, Georg, Maler, Juan Manuel, Otto, Markus, Kornhuber, Johannes, Wiltfang, Jens

“…Cerebrospinal fluid (CSF) concentrations of total Tau and Tau phosphorylated at threonine (position 181 [pTau181]) were studied with ELISA in a group of…”
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