Search Results - "Bibilashvili, R. Sh"
-
1
Peptide Inhibitors of the Interaction of the SARS-CoV-2 Receptor-Binding Domain with the ACE2 Cell Receptor
Published in Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry (2021)“…Computer simulation has been used to identify peptides that mimic the natural target of the SARS-CoV-2 coronavirus spike (S) protein, the…”
Get full text
Journal Article -
2
Fibrinolytics: from the thrombolysis to the processes of blood vessels growth and remodeling, neurogenesis, carcinogenesis and fibrosis
Published in Terapevtic̆eskii arhiv (15-09-2019)“…One of the most outstanding scientific achievements in the thrombolysis is the development and administration of fibrinolysin - the first Soviet drug that…”
Get full text
Journal Article -
3
Proteolytically Inactive Recombinant Forms of Urokinase Suppress Migration of Endothelial Cells
Published in Bulletin of experimental biology and medicine (01-04-2014)“…Proteolytically inactive recombinant forms of urokinase (uPAHQ and amino-terminal fragment) inhibit spontaneous migration of endothelial cells; amino-terminal…”
Get full text
Journal Article -
4
TITERS OF ANTIBODIES TO Β1-ADRENOCEPTOR AND M2 CHOLINERGIC RECEPTORS IN PATIENTS WITH VENTRICULAR ARRHYTHMIAS WITHOUT AN ORGANIC CARDIOVASCULAR DISEASE AND THEIR POSSIBLE CLINICAL SIGNIFICANCE
Published in Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii (01-12-2015)“…Aim. To identify the most promising epitopes that simulate various sites β1-adrenergic and M2-cholinergic receptors, and to evaluate their possible…”
Get full text
Journal Article -
5
Novel conformational peptide antigen, which simulates an immunodominant epitope of the 2nd extracellular loop of β1-adrenoceptor. Computer simulation, synthesis, spatial structure
Published in Bioorganicheskaia khimiia (01-11-2013)“…By means of computer simulation has been built polypeptide antigen conformational structure that imitates the immunodominant epitope of the 2nd extracellular…”
Get more information
Journal Article -
6
Sequencing and analysis of aMycoplasma gallisepticum A5969 chromosome region containing the S10 andrrn23-5 operons
Published in Molecular biology (New York) (01-05-2000)“…A 20,115-nt region of theMycoplasma gallisepticum A5959 genome was sequenced (GenBank accession no. AF036708). The region contains therrn23-5 and S10 operons,…”
Get full text
Journal Article -
7
Expression of a deleted variant of human plasminogen in Escherichia coli
Published in Applied biochemistry and microbiology (01-12-2010)“…A recombinant plasmid carrying a modified gene of human plasminogen (mini-plasminogen), lacking four kringle domains and an amino terminal fragment, and…”
Get full text
Journal Article -
8
Adaptation to physical exercise increases expression of Ca-ATPase gene in myocardial sarcoplasmic reticulum
Published in Bulletin of experimental biology and medicine (01-07-1999)“…Gene expression of the key enzyme of the myocardial sarcoplasmic reticulum Ca^sup 2+^-pump, SERCA-2a isoform was assayed in rats during adaptation to physical…”
Get full text
Journal Article -
9
ТИТРЫ АНТИТЕЛ К β1-АДРЕНОРЕЦЕПТОРАМ И М2-ХОЛИНОРЕЦЕПТОРАМ У БОЛЬНЫХ С ЖЕЛУДОЧКОВЫМИ НАРУШЕНИЯМИ РИТМА СЕРДЦА БЕЗ ПРИЗНАКОВ ОРГАНИЧЕСКОГО ЗАБОЛЕВАНИЯ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ И ИХ ВОЗМОЖНОЕ КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ
Published in Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii (01-12-2015)“…Aim. To identify the most promising epitopes that simulate various sites β1-adrenergic and M2-cholinergic receptors, and to evaluate their possible…”
Get full text
Journal Article -
10
Novel conformational peptide antigen which simulates an immunodominant epitope of the 2nd extracellular loop of β1-adrenoreceptor: Computer simulation, synthesis, spatial structure
Published in Russian journal of bioorganic chemistry (01-11-2013)“…By the means of computer simulation, the polypeptide antigen conformational structure that initiates the immunodominant epitope of the 2nd extracellular loop…”
Get full text
Journal Article -
11
Comparative transcriptome analysis of human aorta atherosclerotic lesions and peripheral blood leukocytes from essential hypertension patients
Published in Kardiologiia (2009)“…One of the major cardiovascular risk factor which predisposes to and accelerates atherosclerosis is arterial hypertension (AH). To determine the molecular…”
Get more information
Journal Article -
12
Interaction between RNA molecules of a two-componet trans-analog of antigenomic HDV-ribozyme
Published in Molekuliarnaia biologiia (01-01-2006)“…Association of RNA molecules forming a two-component B:LS trans-analog of antigenomic HDV ribozyme was studied. From previously synthesized trans-ribozymes the…”
Get more information
Journal Article -
13
Local fibrinolysis of hypertensive intracerebral hematomas
Published in Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko (01-07-2008)“…Authors presented the results of experimental and clinical studies of effects of recombinant prourokinase on brain tissue, its toxicity and safety in…”
Get more information
Journal Article -
14
Properties of antigenomic HDV ribozyme consisting of two RNA chains
Published in Molekuliarnaia biologiia (01-11-2004)“…B : LS ribozyme, a trans-variant of naturally occurring HDV ribozyme, has been constructed. The ribozyme consists of a substrate-containing LS chain and an…”
Get more information
Journal Article -
15
Phospholipase A2, group IIa, as an earlier unknown immunohistological marker of cardiac myxoma
Published in Arkhiv patologii (01-03-2008)“…Phospholipase A2, group IIA, gene expression has been analyzed in primary heart tumors. High expression has been demonstrated through several ways:…”
Get more information
Journal Article -
16
Gene expression analysis in myocytes of right atrial appendages in patients with atrial fibrillation using cDNA microarray technique
Published in Kardiologiia (2008)“…Gene expression level of 2900 genes was studied by cDNA microarray in patients with atrial fibril-lation (AF) or sinus rhythm. Gene transcripts were analysed…”
Get more information
Journal Article -
17
A physical map of Mycoplasma gallisepticum strain A5969 genome and determination of its positions on certain genes
Published in Molekuliarnaia biologiia (01-05-1996)Get more information
Journal Article -
18
A kinetic model of the cleavage of permutational variants of the antigenomic HDV-ribozyme
Published in Molekuliarnaia biologiia (01-09-2001)“…The kinetic characteristics have been studied for noncircularly permuted variants of the human hepatitis delta virus (HDV) antigenomic ribozyme to find out the…”
Get more information
Journal Article -
19
-
20
PRKAR1A gene mutations in two patients with myxoma syndrome (Carney complex)
Published in Kardiologiia (2003)“…Carney complex is an autosomic dominant disorder initially described as the association of cardiac myxomas, spotty skin pigmentation and endocrine overactivity…”
Get more information
Journal Article