Search Results - "Biber, K."

Microglia phenotype diversity by Olah, M, Biber, K, Vinet, J, Boddeke, H W G M

“…Microglia, the tissue macrophages of the brain, have under healthy conditions a resting phenotype that is characterized by a ramified morphology. With their…”
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In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed by Vainchtein, I. D., Vinet, J., Brouwer, N., Brendecke, S., Biagini, G., Biber, K., Boddeke, H. W. G. M., Eggen, B. J. L.

“…Multiple sclerosis (MS) is an autoimmune demyelinating disorder of the central nervous system (CNS) characterized by loss of myelin accompanied by infiltration…”
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Neuronal chemokines: versatile messengers in central nervous system cell interaction by de Haas, A H, van Weering, H R J, de Jong, E K, Boddeke, H W G M, Biber, K P H

“…Whereas chemokines are well known for their ability to induce cell migration, only recently it became evident that chemokines also control a variety of other…”
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Purinergic modulation of glutamate transmission: An expanding role in stress-linked neuropathology by Mayhew, J., Graham, B.A., Biber, K., Nilsson, M., Walker, F.R.

“…•Purinergic signalling from neurons and glia are utilised to modulate glutamate transmission.•Astrocytes and microglia monitor glutamate levels as indicators…”
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Neuron-microglia signaling: Chemokines as versatile messengers by Biber, K, Vinet, J, Boddeke, H.W.G.M

“…Abstract Our understanding of microglia biology has significantly changed in the last couple of years. Instead of being predominantly detrimental cells showing…”
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Inhibition of CXCR3‐mediated chemotaxis by the human chemokine receptor‐like protein CCX‐CKR by Vinet, J, Zwam, M, Dijkstra, IM, Brouwer, N, Weering, HRJ, Watts, A, Meijer, M, Fokkens, MR, Kannan, V, Verzijl, D, Vischer, HF, Smit, MJ, Leurs, R, Biber, K, Boddeke, HWGM

“…Background and Purpose Induction of cellular migration is the primary effect of chemokine receptor activation. However, several chemokine receptor‐like…”
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Functional expression of CXCR3 in cultured mouse and human astrocytes and microglia by Biber, K, Dijkstra, I, Trebst, C, De Groot, C.J.A, Ransohoff, R.M, Boddeke, H.W.G.M

“…It has been established recently that inflammation of the CNS is accompanied by an expression of chemokines within the CNS. Several lines of evidence suggest…”
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Challenge with innate and protein antigens induces CCR7 expression by microglia in vitro and in vivo by Dijkstra, I. M., de Haas, A. H., Brouwer, N., Boddeke, H. W. G. M., Biber, K.

“…Since activated microglia are able to phagocytose damaged cells and subsequently express major histocompatibility complex class II (MHC‐II) and co‐stimulatory…”
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The role of CXC chemokine ligand (CXCL)12-CXC chemokine receptor (CXCR)4 signalling in the migration of neural stem cells towards a brain tumour by Van Der Meulen, A. A. E., Biber, K., Lukovac, S., Balasubramaniyan, V., Den Dunnen, W. F. A., Boddeke, H. W. G. M., Mooij, J. J. A.

“…Aims: It has been shown that neural stem cells (NSCs) migrate towards areas of brain injury or brain tumours and that NSCs have the capacity to track…”
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Expression of interleukin-1 beta in rat dorsal root ganglia by Copray, J.C.V.M., Mantingh, I., Brouwer, N., Biber, K., Küst, B.M., Liem, R.S.B., Huitinga, I., Tilders, F.J.H., Van Dam, A.-M., Boddeke, H.W.G.M.

“…The expression of interleukin-1β was examined in dorsal root ganglion (DRG) neurons from adult rats using non-radioactive in situ hybridization and…”
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Induction of glial L-CCR mRNA expression in spinal cord and brain in experimental autoimmune encephalomyelitis by Brouwer, N., Zuurman, M.W., Wei, T., Ransohoff, R.M., Boddeke, H.W.G.M., Biber, K.

“…Chemokines and chemokine receptors are important regulators of leukocyte trafficking and immune response. It is well established that chemokines and their…”
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Expansion of HPCs from cord blood in a novel 3D matrix by Ehring, B., Biber, K., Upton, T.M., Plosky, D., Pykett, M., Rosenzweig, M.

“…An optimal system for the expansion of pluripotent HPCs would ideally eliminate the use of cytokines and animal-derived serum. We have shown previously that a…”
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Interleukin-6 Enhances Expression of Adenosine A1 Receptor mRNA and Signaling in Cultured Rat Cortical Astrocytes and Brain Slices by Biber, Knut, Lubrich, Beate, Fiebich, Bernd L, Boddeke, Hendrikus W.G.M, van Calker, Dietrich

“…The inhibitory neuromodulator adenosine is released in the brain in high concentrations under conditions of exaggerated neuronal activity such as ischemia and…”
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Age-related myelin degradation burdens the clearance function of microglia during aging by Safaiyan, Shima, Kannaiyan, Nirmal, Snaidero, Nicolas, Brioschi, Simone, Biber, Knut, Yona, Simon, Edinger, Aimee L, Jung, Steffen, Rossner, Moritz J, Simons, Mikael

“…Safaiyan et al . demonstrate that myelin fragments progressively pinch off from aged myelin sheaths and are taken up and cleared by microglia. Age-associated…”
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Distinct amyloid-β and tau-associated microglia profiles in Alzheimer’s disease by Gerrits, Emma, Brouwer, Nieske, Kooistra, Susanne M., Woodbury, Maya E., Vermeiren, Yannick, Lambourne, Mirjam, Mulder, Jan, Kummer, Markus, Möller, Thomas, Biber, Knut, Dunnen, Wilfred F. A. den, De Deyn, Peter P., Eggen, Bart J. L., Boddeke, Erik W. G. M.

“…Alzheimer’s disease (AD) is the most prevalent form of dementia and is characterized by abnormal extracellular aggregates of amyloid-β and intraneuronal…”
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Carbamazepine-Induced Upregulation of Adenosine A1-Receptors in Astrocyte Cultures Affects Coupling to the Phosphoinositol Signaling Pathway by Biber, Knut, Fiebich, Bernd L, Gebicke-Härter, Peter, van Calker, Dietrich

“…The anticonvulsant and antibipolar drug carbamazepine (CBZ) is known to act as a specific antagonist at adenosine A1-receptors. After a 3-week application of…”
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IN CRIME'S ARCHIVE: The Cultural Afterlife of Criminal Evidence by Biber, Katherine

“…This article explores the cultural afterlife of criminal evidence. During the criminal trial, strict rules govern the collection, admission and interpretation…”
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Neuronal ‘On’ and ‘Off’ signals control microglia by Biber, Knut, Neumann, Harald, Inoue, Kazuhide, Boddeke, Hendrikus W.G.M

“…Recent findings indicate that neurons are not merely passive targets of microglia but rather control microglial activity. The variety of different signals that…”
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Neuronal Chemokines: Versatile Messengers In Central Nervous System Cell Interaction by de Haas, A. H., van Weering, H. R. J., de Jong, E. K., Boddeke, H. W. G. M., Biber, K. P. H.

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Effects of In Utero Alcohol Exposure on B-Cell Development in the Murine Fetal Liver by Biber, Kristen L., Moscatello, Kim M., Dempsey, Deborah C., Chervenak, Robert, Wolcott, R. Michael

“…Fetal alcohol syndrome is one of the leading causes of birth defects in this country. Children exposed to alcohol in utero suffer from growth and mental…”
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