Search Results - "Biasi, Sara"

Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia by De Biasi, Sara, Meschiari, Marianna, Gibellini, Lara, Bellinazzi, Caterina, Borella, Rebecca, Fidanza, Lucia, Gozzi, Licia, Iannone, Anna, Lo Tartaro, Domenico, Mattioli, Marco, Paolini, Annamaria, Menozzi, Marianna, Milić, Jovana, Franceschi, Giacomo, Fantini, Riccardo, Tonelli, Roberto, Sita, Marco, Sarti, Mario, Trenti, Tommaso, Brugioni, Lucio, Cicchetti, Luca, Facchinetti, Fabio, Pietrangelo, Antonello, Clini, Enrico, Girardis, Massimo, Guaraldi, Giovanni, Mussini, Cristina, Cossarizza, Andrea

“…The immune system of patients infected by SARS-CoV-2 is severely impaired. Detailed investigation of T cells and cytokine production in patients affected by…”
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Identification and characterization of a SARS-CoV-2 specific CD8+ T cell response with immunodominant features by Gangaev, Anastasia, Ketelaars, Steven L. C., Isaeva, Olga I., Patiwael, Sanne, Dopler, Anna, Hoefakker, Kelly, De Biasi, Sara, Gibellini, Lara, Mussini, Cristina, Guaraldi, Giovanni, Girardis, Massimo, Ormeno, Cami M. P. Talavera, Hekking, Paul J. M., Lardy, Neubury M., Toebes, Mireille, Balderas, Robert, Schumacher, Ton N., Ovaa, Huib, Cossarizza, Andrea, Kvistborg, Pia

“…The COVID-19 pandemic caused by SARS-CoV-2 is a continuous challenge worldwide, and there is an urgent need to map the landscape of immunogenic and…”
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Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy by De Biasi, Sara, Gibellini, Lara, Lo Tartaro, Domenico, Puccio, Simone, Rabacchi, Claudio, Mazza, Emilia M. C., Brummelman, Jolanda, Williams, Brandon, Kaihara, Kelly, Forcato, Mattia, Bicciato, Silvio, Pinti, Marcello, Depenni, Roberta, Sabbatini, Roberto, Longo, Caterina, Dominici, Massimo, Pellacani, Giovanni, Lugli, Enrico, Cossarizza, Andrea

“…Immune checkpoint inhibitors are used for treating patients with metastatic melanoma. Since the response to treatment is variable, biomarkers are urgently…”
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Monocyte Distribution Width (MDW) as novel inflammatory marker with prognostic significance in COVID-19 patients by Riva, Giovanni, Castellano, Sara, Nasillo, Vincenzo, Ottomano, Anna Maria, Bergonzini, Giuliano, Paolini, Ambra, Lusenti, Beatrice, Milić, Jovana, De Biasi, Sara, Gibellini, Lara, Cossarizza, Andrea, Busani, Stefano, Girardis, Massimo, Guaraldi, Giovanni, Mussini, Cristina, Manfredini, Rossella, Luppi, Mario, Tagliafico, Enrico, Trenti, Tommaso

“…Monocyte Distribution Width (MDW), a new cytometric parameter correlating with cytomorphologic changes occurring upon massive monocyte activation, has recently…”
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Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection by De Biasi, Sara, Tartaro, Domenico Lo, Gibellini, Lara, Paolini, Annamaria, Quong, Andrew, Petes, Carlene, Awong, Geneve, Douglas, Samuel, Lin, Dongxia, Nieto, Jordan, Galassi, Francesco Maria, Borella, Rebecca, Fidanza, Lucia, Mattioli, Marco, Leone, Chiara, Neri, Isabella, Meschiari, Marianna, Cicchetti, Luca, Iannone, Anna, Trenti, Tommaso, Sarti, Mario, Girardis, Massimo, Guaraldi, Giovanni, Mussini, Cristina, Facchinetti, Fabio, Cossarizza, Andrea

“…SARS-CoV-2 infection can affect all human beings, including pregnant women. Thus, understanding the immunological changes induced by the virus during pregnancy…”
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Interfering with ROS Metabolism in Cancer Cells: The Potential Role of Quercetin by Gibellini, Lara, Pinti, Marcello, Nasi, Milena, De Biasi, Sara, Roat, Erika, Bertoncelli, Linda, Cossarizza, Andrea

“…A main feature of cancer cells, when compared to normal ones, is a persistent pro-oxidative state that leads to an intrinsic oxidative stress. Cancer cells…”
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Hypokalemia in Patients with COVID-19 by Alfano, Gaetano, Ferrari, Annachiara, Fontana, Francesco, Perrone, Rossella, Mori, Giacomo, Ascione, Elisabetta, Magistroni, Riccardo, Venturi, Giulia, Pederzoli, Simone, Margiotta, Gianluca, Romeo, Marilina, Piccinini, Francesca, Franceschi, Giacomo, Volpi, Sara, Faltoni, Matteo, Ciusa, Giacomo, Bacca, Erica, Tutone, Marco, Raimondi, Alessandro, Menozzi, Marianna, Franceschini, Erica, Cuomo, Gianluca, Orlando, Gabriella, Santoro, Antonella, Di Gaetano, Margherita, Puzzolante, Cinzia, Carli, Federica, Bedini, Andrea, Milic, Jovana, Meschiari, Marianna, Mussini, Cristina, Cappelli, Gianni, Guaraldi, Giovanni

“…Background Patients with COVID-19 experience multiple clinical conditions that may cause electrolyte imbalances. Hypokalemia is a concerning electrolyte…”
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Risk of SARS-CoV-2 reinfection by vaccination status, predominant variant and time from prior infection: a cohort study, Reggio Emilia province, Italy, February 2020 to February 2022 by Vicentini, Massimo, Venturelli, Francesco, Mancuso, Pamela, Bisaccia, Eufemia, Zerbini, Alessandro, Massari, Marco, Cossarizza, Andrea, De Biasi, Sara, Pezzotti, Patrizio, Bedeschi, Emanuela, Giorgi Rossi, Paolo

“…BackgroundUnderstanding the epidemiology of reinfections is crucial for SARS-CoV-2 control over a long period.AimTo evaluate the risk of SARS-CoV-2 reinfection…”
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Mitochondrial damage-associated molecular patterns stimulate reactive oxygen species production in human microglia by Nasi, Milena, De Gaetano, Anna, Bianchini, Elena, De Biasi, Sara, Gibellini, Lara, Neroni, Anita, Mattioli, Marco, Pinti, Marcello, Lo Tartaro, Domenico, Borella, Rebecca, Mattioli, Anna Vittoria, Chester, Johanna, Melegari, Alessandra, Simone, Anna Maria, Ferraro, Diana, Vitetta, Francesca, Sola, Patrizia, Cossarizza, Andrea

“…Microglia are the resident innate immune cells of the central nervous system and exert functions of host defense and maintenance of normal tissue homeostasis,…”
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NLRP3 and IL-1β Gene Expression Is Elevated in Monocytes From HIV-Treated Patients With Neurocognitive Disorders by Mazaheri-Tehrani, Elham, Mohraz, Minoo, Nasi, Milena, Chester, Johanna, De Gaetano, Anna, Lo Tartaro, Domenico, SeyedAlinaghi, SeyedAhmad, Gholami, Mohammad, De Biasi, Sara, Gibellini, Lara, Mattioli, Anna Vittoria, Pinti, Marcello, Mussini, Cristina, Cossarizza, Andrea

“…BACKGROUND:Systemic immune activation and inflammation in chronic HIV infection are driving factors of non-AIDS related events, including neurocognitive…”
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Innovative Flow Cytometry Allows Accurate Identification of Rare Circulating Cells Involved in Endothelial Dysfunction by Boraldi, Federica, Bartolomeo, Angelica, De Biasi, Sara, Orlando, Stefania, Costa, Sonia, Cossarizza, Andrea, Quaglino, Daniela

“…Although rare, circulating endothelial and progenitor cells could be considered as markers of endothelial damage and repair potential, possibly predicting the…”
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Author Correction: Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection by De Biasi, Sara, Tartaro, Domenico Lo, Gibellini, Lara, Paolini, Annamaria, Quong, Andrew, Petes, Carlene, Awong, Geneve, Douglas, Samuel, Lin, Dongxia, Nieto, Jordan, Galassi, Francesco Maria, Borella, Rebecca, Fidanza, Lucia, Mattioli, Marco, Leone, Chiara, Neri, Isabella, Meschiari, Marianna, Cicchetti, Luca, Iannone, Anna, Trenti, Tommaso, Sarti, Mario, Girardis, Massimo, Guaraldi, Giovanni, Mussini, Cristina, Facchinetti, Fabio, Cossarizza, Andrea

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Analysis of inflammasomes and antiviral sensing components reveals decreased expression of NLRX1 in HIV-positive patients assuming efficient antiretroviral therapy by Nasi, Milena, De Biasi, Sara, Bianchini, Elena, Digaetano, Margherita, Pinti, Marcello, Gibellini, Lara, Pecorini, Simone, Carnevale, Gianluca, Guaraldi, Giovanni, Borghi, Vanni, Mussini, Cristina, Cossarizza, Andrea

“…OBJECTIVE:Few studies have investigated the importance of different components of the inflammasome system and of innate mitochondrial sensing (IMS) pathways in…”
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Acid base disorders in patients with COVID-19 by Alfano, Gaetano, Fontana, Francesco, Mori, Giacomo, Giaroni, Francesco, Ferrari, Annachiara, Giovanella, Silvia, Ligabue, Giulia, Ascione, Elisabetta, Cazzato, Silvia, Ballestri, Marco, Di Gaetano, Margherita, Meschiari, Marianna, Menozzi, Marianna, Milic, Jovana, Andrea, Bedini, Franceschini, Erica, Cuomo, Gianluca, Magistroni, Riccardo, Mussini, Cristina, Cappelli, Gianni, Guaraldi, Giovanni

“…Purpose Acid–base derangement has been poorly described in patients with coronavirus disease 2019 (COVID-19). Considering the high prevalence of pneumonia and…”
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Editorial: Deciphering the T cell response in SARS-CoV-2 infection by Maggi, Laura, Mazzoni, Alessio, De Biasi, Sara

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DNA Topoisomerase I differentially modulates R-loops across the human genome by Manzo, Stefano G, Hartono, Stella R, Sanz, Lionel A, Marinello, Jessica, De Biasi, Sara, Cossarizza, Andrea, Capranico, Giovanni, Chedin, Frederic

“…Co-transcriptional R-loops are abundant non-B DNA structures in mammalian genomes. DNA Topoisomerase I (Top1) is often thought to regulate R-loop formation…”
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Immunological signature in human cases of monkeypox infection in 2022 outbreak: an observational study by Agrati, Chiara, Cossarizza, Andrea, Mazzotta, Valentina, Grassi, Germana, Casetti, Rita, De Biasi, Sara, Pinnetti, Carmela, Gili, Simona, Mondi, Annalisa, Cristofanelli, Flavia, Lo Tartaro, Domenico, Notari, Stefania, Maffongelli, Gaetano, Gagliardini, Roberta, Gibellini, Lara, Aguglia, Camilla, Lanini, Simone, D'Abramo, Alessandra, Matusali, Giulia, Fontana, Carla, Nicastri, Emanuele, Maggi, Fabrizio, Girardi, Enrico, Vaia, Francesco, Antinori, Andrea

“…An unprecedented global monkeypox outbreak started in May, 2022. No data are yet available about the dynamics of the immune response against monkeypox virus…”
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Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia by Gibellini, Lara, De Biasi, Sara, Paolini, Annamaria, Borella, Rebecca, Boraldi, Federica, Mattioli, Marco, Lo Tartaro, Domenico, Fidanza, Lucia, Caro‐Maldonado, Alfredo, Meschiari, Marianna, Iadisernia, Vittorio, Bacca, Erica, Riva, Giovanni, Cicchetti, Luca, Quaglino, Daniela, Guaraldi, Giovanni, Busani, Stefano, Girardis, Massimo, Mussini, Cristina, Cossarizza, Andrea

“…In patients infected by SARS‐CoV‐2 who experience an exaggerated inflammation leading to pneumonia, monocytes likely play a major role but have received poor…”
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Emerging role of Lon protease as a master regulator of mitochondrial functions by Pinti, Marcello, Gibellini, Lara, Nasi, Milena, De Biasi, Sara, Bortolotti, Carlo Augusto, Iannone, Anna, Cossarizza, Andrea

“…Lon protease is a nuclear-encoded, mitochondrial ATP-dependent protease highly conserved throughout the evolution, crucial for the maintenance of mitochondrial…”
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Finding predictive factors for immunotherapy in metastatic renal-cell carcinoma: What are we looking for? by Guida, Annalisa, Sabbatini, Roberto, Gibellini, Lara, De Biasi, Sara, Cossarizza, Andrea, Porta, Camillo

“…•Immune-based combinations have led to marked improvements in OS in mRCC.•One major challenges is to identify a predictive biomarker of response to…”
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