Search Results - "Bianconi, Vanessa"
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The regulation and importance of monocyte chemoattractant protein-1
Published in Current opinion in hematology (01-01-2018)“…PURPOSE OF REVIEWMonocyte chemoattractant protein (MCP)-1, a chemokine regulating monocyte chemotaxis and T-lymphocyte differentiation by binding to the CC…”
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The role of phosphatidylserine recognition receptors in multiple biological functions
Published in Cellular & molecular biology letters (26-03-2020)“…Apoptotic cells are rapidly engulfed and degraded by phagocytes through efferocytosis. Efferocytosis is a highly regulated process. It is triggered upon the…”
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Endothelial and cardiac progenitor cells for cardiovascular repair: A controversial paradigm in cell therapy
Published in Pharmacology & therapeutics (Oxford) (01-01-2018)“…Stem cells have the potential to differentiate into cardiovascular cell lineages and to stimulate tissue regeneration in a paracrine/autocrine manner; thus,…”
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Effects of statins on the biological features of mesenchymal stem cells and therapeutic implications
Published in Heart failure reviews (01-09-2021)“…Statins are well-known lipid-lowering drugs. The pleiotropic effects of statins have brought about some beneficial effects on improving the therapeutic…”
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The Role of Efferocytosis in Autoimmune Diseases
Published in Frontiers in immunology (20-07-2018)“…Apoptosis happens continuously for millions of cells along with the active removal of apoptotic debris in order to maintain tissue homeostasis. In this…”
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PCSK9 at the crossroad of cholesterol metabolism and immune function during infections
Published in Journal of cellular physiology (01-09-2017)“…Sepsis, a complex and dynamic syndrome resulting from microbial invasion and immune system dysregulation, is associated with an increased mortality, reaching…”
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The role of TFEB in tumor cell autophagy: Diagnostic and therapeutic opportunities
Published in Life sciences (1973) (01-03-2020)“…Autophagy is a conserved “self-eating” recycling process which removes aggregated or misfolded proteins, or defective organelles, to maintain cellular…”
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Lipoprotein(a) and inflammation: A dangerous duet leading to endothelial loss of integrity
Published in Pharmacological research (01-05-2017)“…[Display omitted] Lp(a), inflammation and endothelial injury. Lipoprotein(a) [Lp(a)] is an enigmatic lipoprotein whose ancestral useful properties have been…”
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Beyond cholesterol metabolism: The pleiotropic effects of proprotein convertase subtilisin/kexin type 9 (PCSK9). Genetics, mutations, expression, and perspective for long‐term inhibition
Published in BioFactors (Oxford) (01-05-2020)“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) has a crucial role in lipid metabolism, particularly due to its function in low‐density lipoprotein…”
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Resolution of Inflammation in Neurodegenerative Diseases: The Role of Resolvins
Published in Mediators of inflammation (2020)“…Acute inflammation has been described as a reactive dynamic process, promoted by the secretion of proinflammatory mediators, including lipid molecules like…”
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Treatment with proton pump inhibitors is associated with secondary bacterial infections and sepsis in patients with COVID-19: a retrospective analysis of their joint impact on in-hospital prognosis
Published in Annals of medicine (Helsinki) (01-12-2024)“…Secondary bacterial infections (SBIs) contribute to worse in-hospital outcomes in patients with Coronavirus disease 2019 (COVID-19). Treatment with proton pump…”
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Effect of Statins on Prevalence and Mortality of Influenza Virus Infection: A Systematic Review and Meta-Analysis
Published in Archives of medical science (07-11-2022)“…Introduction The aim of this meta-analysis was to assess the effect of ongoing statin treatment on susceptibility to influenza virus infection and on…”
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Regulation of cardiac stem cells by microRNAs: State-of-the-art
Published in Biomedicine & pharmacotherapy (01-12-2019)“…Stem cells have a therapeutic potential in various medical conditions. In cases without sufficient response to conventional drug treatments, stem cells…”
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Statins Attenuate Fibrotic Manifestations of Cardiac Tissue Damage
Published in Current molecular pharmacology (01-01-2021)“…Cardiac fibrosis is a maladaptive condition secondary to cardiomyopathy caused by a wide spectrum of stimuli, including myocardial infarction (MI), pressure…”
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Effect of Statin Therapy on Arterial Wall Inflammation Based on 18F-FDG PET/CT: A Systematic Review and Meta-Analysis of Interventional Studies
Published in Journal of clinical medicine (18-01-2019)“…To evaluate by meta-analysis of interventional studies the effect of statin therapy on arterial wall inflammation. Arterial exposure to low-density lipoprotein…”
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A tryptophan metabolite prevents depletion of circulating endothelial progenitor cells in systemic low-grade inflammation
Published in Frontiers in immunology (04-04-2023)“…Chronic systemic inflammation reduces the bioavailability of circulating endothelial progenitor cells (EPCs). Indoleamine 2,3-dioxygenase 1 (IDO1), a key…”
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Exploring the Link between Plasma Levels of PCSK9, Immune Dysregulation and Atherosclerosis in Patients with Primary Sjögren’s Syndrome
Published in Biomolecules (Basel, Switzerland) (01-09-2023)“…Proprotein convertase subtilisin/kexin type 9 (PCSK9) regulates lipid metabolism contributing to cardiovascular (CV) risk in the general population. The…”
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Time-related changes in sex distribution of COVID-19 incidence proportion in Italy
Published in Heliyon (01-10-2020)“…Variable sex-disaggregated data on Coronavirus disease 2019 (COVID-19) incidence proportion (IP) have been reported in different datasets and studies. Factors…”
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The Association between HDL-C and Subclinical Atherosclerosis Depends on CETP Plasma Concentration: Insights from the IMPROVE Study
Published in Biomedicines (11-03-2021)“…The impact of cholesteryl ester transfer protein (CETP) on atherosclerosis is highly debated. This study aimed to investigate the associations between plasma…”
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Why patients with familial hypercholesterolemia are at high cardiovascular risk? Beyond LDL-C levels
Published in Trends in cardiovascular medicine (01-05-2021)“…Familial hypercholesterolemia (FH) is a common genetic cause of elevated low-density lipoprotein cholesterol (LDL-C) due to defective clearance of circulating…”
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