Search Results - "Bianchino, Erminia"
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Differential effect of 2-hydroxyoleic acid enantiomers on protein (sphingomyelin synthase) and lipid (membrane) targets
Published in Biochimica et biophysica acta (01-06-2014)“…The complex dual mechanism of action of 2-hydroxyoleic acid (2OHOA), a potent anti-tumor compound used in membrane lipid therapy (MLT), has yet to be fully…”
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Antioxidant activity of diphenylpropionamide derivatives: synthesis, biological evaluation and computational analysis
Published in Molecules (Basel, Switzerland) (28-03-2008)“…We report the synthesis, antioxidant and antiproliferative activity and a QSAR analysis of synthetic diphenylpropionamide derivatives. Synthesis of these…”
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Camptothecin-psammaplin A hybrids as topoisomerase I and HDAC dual-action inhibitors
Published in European journal of medicinal chemistry (01-01-2018)“…Recent studies have demonstrated enhanced anticancer effects of combination therapy consisting of camptothecin derivatives and HDAC inhibitors. To exploit this…”
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The effect of hydroxylated fatty acid-containing phospholipids in the remodeling of lipid membranes
Published in Biochimica et biophysica acta (01-06-2014)“…The synthetic fatty acid 2-hydroxyoleic acid (2OHOA) is an antitumor drug that regulates membrane lipid composition and structure. An important effect of this…”
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Abstract 2936: Molecular profiling of primary malignant pleuralmesothelioma histotypes cell lines reveals relationship between GDF15overexpression and cisplatin resistance both in in vitro and in vivo models
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Malignant pleural mesothelioma (MPM) development is mainly correlated with exposure to asbestos and appears to be a trend toward an increase in its incidence…”
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QSAR analysis on antimicrobial peptides
Published in Chemistry and physics of lipids (01-09-2007)Get full text
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Abstract 5556: Mice models of three human mesothelioma histotypes derived from primary patient tumors
Published in Cancer research (Chicago, Ill.) (01-10-2014)“…Mesothelioma, sometimes referred to as asbestos cancer, is known to be among the most aggressive and difficult to treat tumours. The disease attacks the…”
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