Search Results - "Bianchi, R G"

Polymer delivery of the active isomer of misoprostol: a solution to the intestinal side effect problem by Perkins, W E, Bianchi, R G, Tremont, S J, Collins, P W, Casler, J J, Fenton, R L, Wagner, G M, McGrath, M P, Stolzenbach, J C, Kowalski, D L

“…SC-53450 is a new polybutadiene-based polymer system with an acid labile diisopropyl silyl ether linker to which the active isomer of misoprostol (SC-30249) is…”
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Polymeric delivery of the active isomer of misoprostol reduces systemic availability and uterotonic activity by Gullikson, G W, Loeffler, R F, Mehrotra, D V, Casler, J J, Bianchi, R G, Schmidt, R E, Khoshaba, N, Perkins, W E

“…SC-30249 is the active isomer of misoprostol responsible for its mucosal protective effects against nonsteroidal anti-inflammatory drugs (NSAIDS). Linkage of…”
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Synthesis and structure-activity relationships of acyclic .omega. chain conjugated diene analogs of enisoprost by Collins, P. W, Shone, R. L, Perkins, W. E, Gasiecki, A. F, Kalish, V. J, Kramer, S. W, Bianchi, R. G

“…A series of acyclic omega chain conjugated diene analogues of enisoprost were synthesized and evaluated for gastric antisecretory and diarrheagenic activities…”
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Chemistry and structure-activity relationships of C-17 unsaturated 18-cycloalkyl and cycloalkenyl analogs of enisoprost. Identification of a promising new antiulcer prostaglandin by Collins, P. W, Gasiecki, A. F, Perkins, W. E, Gullikson, G. W, Bianchi, R. G, Kramer, S. W, Ng, J. S, Yonan, E. E, Swenton, L

“…A series of delta 17 unsaturated cycloalkyl and cycloalkenyl analogues of enisoprost was synthesized to investigate the effects of omega chain unsaturation on…”
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PRESBYOPIA MANAGEMENT WITH DIFFRACTIVE PHAKIC POSTERIOR CHAMBER IOL by Bianchi, G R

“…To evaluate safety and refractive efficiency after posterior chamber diffractive implantable phakic contact lens (IPCL) surgery. A prospective non-randomized…”
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Catalytic functionalization of polymers: a novel approach to site-specific delivery of misoprostol to the stomach by Tremont, Samuel J, Collins, Paul W, Perkins, William E, Fenton, Rick L, Forster, Denis, McGrath, Martin P, Wagner, Grace M, Gasiecki, Alan F, Bianchi, Robert G

“…The application of functionalized polymers to site-directed delivery of the antiulcer prostaglandin, misoprostol, is described. By use of homogeneous…”
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Characterization of prostaglandin E receptors in canine small intestine using [3H] prostaglandin E1 binding by Keith, R H, Tsai, B S, Collins, P W, Perkins, W E, Shone, R L, Gasiecki, A F, Bianchi, R G, Bauer, R F

“…Prostaglandin E (PGE) receptors in canine small intestinal mucosal and muscle membrane preparations were labeled with [3H] PGE1. Saturable, high affinity…”
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Comparative mucosal protective properties of misoprostol, cimetidine, and sucralfate by Bauer, R F, Bianchi, R G, Casler, J, Goldstin, B

“…Misoprostol, a PGE1 derivative that inhibits gastric acid secretion in rats, was compared with cimetidine and sucralfate in several rat experimental ulcer…”
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Synergistic actions of propantheline bromide with cimetidine and thiopropazate hydrochloride in the prevention of stress ulcer formation in rats by Dajani, E Z, Bianchi, R G, Calhoun, D W

“…The effects of propantheline bromide (PB), cimetidine (CM) and thiopropazate hydrochloride (TP) on the course of stress ulcer formation were investigated…”
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The pharmacology of SC-27166: a novel antidiarrheal agent by Dajani, E Z, Bianchi, R G, East, P F, Bloss, J L, Adelstein, G W, Yen, C H

“…SC-27166 is the result of continuing efforts to discover selective and orally active antidiarrheal agents. SC-27166, which is chemically unrelated to opiates…”
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Synthesis and gastrointestinal pharmacology of a 3E,5Z diene analog of misoprostol by Collins, Paul W, Kramer, Steven W, Gasiecki, Alan F, Weier, Richard M, Jones, Peter H, Gullikson, Gary W, Bianchi, Robert G, Bauer, Raymond F

“…A stereospecific synthesis and the gastric antisecretory and diarrheal activity of a 3E,5Z diene analogue of misoprostol are described. The key intermediate in…”
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Inhibition of intestinal secretion in the dog: a new approach for the management of diarrheal states by Gullikson, G W, Dajani, E Z, Bianchi, R G

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Synthesis and gastric antisecretory properties of .alpha.-chain diene derivatives of misoprostol by Collins, Paul W, Gasiecki, Alan F, Jones, Peter H, Bauer, Raymond F, Gullikson, Gary W, Woods, Emmett M, Bianchi, Robert G

“…The synthesis and gastric antisecretory activity in dogs of seven alpha chain diene derivatives of misoprostol are described. The key intermediates in the…”
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ANTIPEPTIC AND ANTIULCEROGENIC PROPERTIES OF A SYNTHETIC SULFATED POLYSACCHARIDE (SN-263) by BIANCHI, R G, COOK, D L

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Mechanism of the antipeptic action of amylopectin sulfate (SN-263), and antiulcer, mucin-like agent by Cammarata, P S, Bianchi, R G, Fago, F J

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The effect of certain tranquilizers on intrabiliary pressure of cholecystectomized dogs by BIANCHI, R G, CRAIG, R L

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The effect of hyaluronidase on experimental intestinal adhesions in the rat by CRAIG, R L, BIANCHI, R G

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Gastric antisecretory effects of propantheline bromide and metiamide in rhesus monkeys by Dajani, E Z, Callison, D A, Bianchi, R G

“…The effects of propantheline bromide (PB) and metiamide (M), two dissimilar classes of gastric secretory inhibitors, were studied in chronic gastric fistula…”
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Renal function studies in the dog hypophysectomized for ascites by Craig, Robert L, Wetzel, Nicholas, Bianchi, Robert G

“…1 Department of Surgery, Northwestern University Medical School; and Division of Biological Research, G. D. Searle & Company, Chicago, Illinois Dogs with…”
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Effects of oral administration of PGE2 on gastric secretion and experimental peptic ulcerations by Lee, Y H, Cheng, W D, Bianchi, R G, Mollison, K, Hansen, J

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