Search Results - "Bian, Kang"
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1
Nickel‐Catalyzed Carbofluoroalkylation of 1,3‐Enynes to Access Structurally Diverse Fluoroalkylated Allenes
Published in Angewandte Chemie International Edition (01-04-2019)“…A nickel‐catalyzed 1,4‐carbofluoroalkylation of 1,3‐enynes to access structurally diverse fluoroalkylated allenes has been established. This method has…”
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2
Investigating the softening of weak interlayers during landslides using nanoindentation experiments and simulations
Published in Engineering geology (01-11-2020)“…Based on nanoindentation experiments and numerical simulations, an approach is developed to investigate the softening of weak interlayers, which might trigger…”
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3
Diversity‐Oriented Synthesis of Aliphatic Fluorides via Reductive C(sp3)−C(sp3) Cross‐Coupling Fluoroalkylation
Published in Angewandte Chemie International Edition (25-06-2021)“…Monofluorinated alkyl compounds are of great importance in pharmaceuticals, agrochemicals and materials. Herein, we describe a direct nickel‐catalyzed…”
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4
A General and Efficient Solution to Monofluoroalkylation: Divergent Synthesis of Aliphatic Monofluorides with Modular Synthetic Scaffolds
Published in Angewandte Chemie International Edition (05-09-2022)“…Monofluoroalkanes are important in many pharmaceuticals, agrochemicals and functional materials. However, the lack of easily available and transformable…”
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5
Enantioselective Synthesis of Secondary β‑Trifluoromethyl Alcohols via Catalytic Asymmetric Reductive Trifluoroalkylation and Diastereoselective Reduction
Published in Journal of the American Chemical Society (13-04-2022)“…Fluorinated motifs are frequently encountered in drugs and agrochemicals. Incorporating fluorine-containing motifs in drug candidates for lead optimization in…”
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6
Photocatalytic hydrofluoroalkylation of alkenes with carboxylic acids
Published in Nature chemistry (01-12-2023)“…Incorporation of fluoroalkyl motifs in pharmaceuticals can enhance the therapeutic profiles of the parent molecules. The hydrofluoroalkylation of alkenes has…”
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7
Photochemical diazidation of alkenes enabled by ligand-to-metal charge transfer and radical ligand transfer
Published in Nature communications (23-12-2022)“…Vicinal diamines are privileged synthetic motifs in chemistry due to their prevalence and powerful applications in bioactive molecules, pharmaceuticals, and…”
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8
Mechanical Behavior and Damage Constitutive Model of Rock Subjected to Water-Weakening Effect and Uniaxial Loading
Published in Rock mechanics and rock engineering (2019)“…Water-weakening effect is one of the most important causes triggering large deformation and failure of soft-rock engineering; however, few studies have paid…”
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9
Photocatalytic, modular difunctionalization of alkenes enabled by ligand-to-metal charge transfer and radical ligand transfer
Published in Chemical science (Cambridge) (20-12-2023)“…Ligand-to-metal charge transfer (LMCT) is a mechanistic strategy that provides a powerful tool to access diverse open-shell species using earth abundant…”
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10
Asymmetric construction of allylicstereogenic carbon center featuring atrifluoromethyl group via enantioselective reductive fluoroalkylation
Published in Nature communications (17-11-2022)“…Emerging as a powerful tool for lead optimization in pharmaceutical research and development, to develop the facile, general protocols that allows the…”
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11
Reliability analysis of slope with cross-correlated spatially variable soil properties using AFOSM
Published in Environmental earth sciences (01-10-2021)“…Efficient approaches for slope reliability computation with spatially variable soil properties are of great interest. In this paper, an advanced first-order…”
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12
Green tea and liver cancer risk: A meta-analysis of prospective cohort studies in Asian populations
Published in Nutrition (Burbank, Los Angeles County, Calif.) (2016)“…Abstract Objectives The aim of this meta-analysis was to investigate whether an association existed between green tea consumption and the risk for liver cancer…”
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13
Radical ligand transfer: a general strategy for radical functionalization
Published in Beilstein journal of organic chemistry (15-08-2023)“…The place of alkyl radicals in organic chemistry has changed markedly over the last several decades, evolving from challenging-to-generate “uncontrollable”…”
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14
Ligand‐Promoted, Enantioconvergent Synthesis of Aliphatic Alkanes Bearing Trifluoromethylated Stereocenters via Hydrotrifluoroalkylation of Unactivated Alkenes
Published in Chinese journal of chemistry (01-07-2022)“…Comprehensive Summary While drug chirality remains one of the most important themes in medicinal chemistry and fluorine‐containing drugs have comprised large…”
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15
Copper-catalyzed formylation of alkenyl C–H bonds using BrCHCl2 as a stoichiometric formylating reagent
Published in Chemical science (Cambridge) (21-03-2018)“…The first example of copper-catalyzed direct formylation of alkenyl C–H bonds for the facile synthesis of α,β-unsaturated aldehydes has been developed. This…”
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16
Highly stereoselective nickel-catalyzed difluoroalkylation of aryl ketones to tetrasubstituted monofluoroalkenes and quaternary alkyl difluorides
Published in Chemical science (Cambridge) (28-10-2019)“…A nickel-catalyzed difluoroalkylation of α-C-H bonds of aryl ketones to furnish highly stereo-defined tetrasubstituted monofluoroalkenes or quaternary alkyl…”
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17
Three-dimensional limit equilibrium method based on a TIN sliding surface
Published in Engineering geology (28-11-2019)“…•TIN sliding surfaces are generated and simplified by the modules in VTK.•A model of the 3D LEM based on the TIN is presented with the Hovland method.•A more…”
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18
Copper-Catalyzed Enantioselective Arylation via Radical-Mediated C–C Bond Cleavage: Synthesis of Chiral ω,ω-Diaryl Alkyl Nitriles
Published in Organic letters (01-10-2021)“…The first example of copper-catalyzed ring-opening, enantioselective arylation of cyclic ketoxime esters to access ω,ω-diaryl alkyl nitriles has been developed…”
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19
Palladium(II)-Catalyzed C(sp2)–H Carbonylation of Sterically Hindered Amines with Carbon Monoxide
Published in Organic letters (19-10-2018)“…A palladium-catalyzed, amine-directed C(sp2)–H carbonylation of α,α-disubstituted benzylamine under 1 atm of CO for the facile synthesis of sterically…”
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20
Cause investigation and verification of lining cracking of bifurcation tunnel at Huizhou Pumped Storage Power Station
Published in Tunnelling and underground space technology (01-04-2016)“…[Display omitted] •Cause investigation and verification of lining cracking of tunnel is studied.•Field survey and exclusive method are used to investigate…”
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