Search Results - "Biamonte, Marco A"

Heat Shock Protein 90: Inhibitors in Clinical Trials by Biamonte, Marco A, Van de Water, Ryan, Arndt, Joseph W, Scannevin, Robert H, Perret, Daniel, Lee, Wen-Cherng

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S9.6-based hybrid capture immunoassay for pathogen detection by Bothra, Ankur, Perry, Megan L., Wei, Elena, Moayeri, Mahtab, Ma, Qian, Biamonte, Marco A., Siirin, Marina, Leppla, Stephen H.

“…The detection of pathogens is critical for clinical diagnosis and public health surveillance. Detection is usually done with nucleic acid-based tests (NATs)…”
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Onchocerciasis: Target product profiles of in vitro diagnostics to support onchocerciasis elimination mapping and mass drug administration stopping decisions by Biamonte, Marco A, Cantey, Paul T, Coulibaly, Yaya I, Gass, Katherine M, Hamill, Louise C, Hanna, Christopher, Lammie, Patrick J, Kamgno, Joseph, Nutman, Thomas B, Oguttu, David W, Sankara, Dieudonné P, Stolk, Wilma A, Unnasch, Thomas R

“…In June 2021, the World Health Organization (WHO), recognizing the need for new diagnostics to support the control and elimination of onchocerciasis, published…”
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A novel rapid test for detecting antibody responses to Loa loa infections by Pedram, Bijan, Pasquetto, Valérie, Drame, Papa M, Ji, Yongchang, Gonzalez-Moa, Maria J, Baldwin, Richard K, Nutman, Thomas B, Biamonte, Marco A

“…Ivermectin-based mass drug administration (MDA) programs have achieved remarkable success towards the elimination of onchocerciasis and lymphatic filariasis…”
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EC144 Is a Potent Inhibitor of the Heat Shock Protein 90 by Shi, Jiandong, Van de Water, Ryan, Hong, Kevin, Lamer, Ryan B, Weichert, Kenneth W, Sandoval, Cristina M, Kasibhatla, Srinivas R, Boehm, Marcus F, Chao, Jianhua, Lundgren, Karen, Timple, Noelito, Lough, Rachel, Ibanez, Gerardo, Boykin, Christina, Burrows, Francis J, Kehry, Marilyn R, Yun, Theodore J, Harning, Erin K, Ambrose, Christine, Thompson, Jeffrey, Bixler, Sarah A, Dunah, Anthone, Snodgrass-Belt, Pamela, Arndt, Joseph, Enyedy, Istvan J, Li, Ping, Hong, Victor S, McKenzie, Andres, Biamonte, Marco A

“…Alkyne 40, 5-(2-amino-4-chloro-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-methylpent-4-yn-2-ol (EC144), is a second…”
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Recent advances in malaria drug discovery by Biamonte, Marco A., Wanner, Jutta, Le Roch, Karine G.

“…This digest covers some of the most relevant progress in malaria drug discovery published between 2010 and 2012. There is an urgent need to develop new…”
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Evaluation of a novel biplex rapid diagnostic test for antibody responses to Loa loa and Onchocerca volvulus infections by Campillo, Jérémy T, Biamonte, Marco A, Hemilembolo, Marlhand C, Missamou, François, Boussinesq, Michel, Pion, Sébastien D S, Chesnais, Cédric B

“…Endemic to Central Africa, loiasis, caused by the vector-borne worm Loa loa, affects approximately 10 million individuals. Clinical manifestations include…”
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Diagnostics and the neglected tropical diseases roadmap: setting the agenda for 2030 by Souza, Ashley A, Ducker, Camilla, Argaw, Daniel, King, Jonathan D, Solomon, Anthony W, Biamonte, Marco A, Coler, Rhea N, Cruz, Israel, Lejon, Veerle, Levecke, Bruno, Marchini, Fabricio K, Marks, Michael, Millet, Pascal, Njenga, Sammy M, Noordin, Rahmah, Paulussen, René, Sreekumar, Esvawaran, Lammie, Patrick J

“…Abstract Accurate and reliable diagnostic tools are an essential requirement for neglected tropical diseases (NTDs) programmes. However, the NTD community has…”
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Correction: Onchocerciasis: Target product profiles of in vitro diagnostics to support onchocerciasis elimination mapping and mass drug administration stopping decisions by Biamonte, Marco A, Cantey, Paul T, Coulibaly, Yaya I, Gass, Katherine M, Hamill, Louise C, Hanna, Christopher, Lammie, Patrick J, Kamgno, Joseph, Nutman, Thomas B, Oguttu, David W, Sankara, Dieudonné P, Stolk, Wilma A, Unnasch, Thomas R

“…[This corrects the article DOI: 10.1371/journal.pntd.0010682.]…”
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Realistically, how far are we from a universal malaria drug? by Biamonte, Marco A

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EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity by Yun, Theodore J, Harning, Erin K, Giza, Keith, Rabah, Dania, Li, Ping, Arndt, Joseph W, Luchetti, David, Biamonte, Marco A, Shi, Jiandong, Lundgren, Karen, Manning, Anthony, Kehry, Marilyn R

“…Heat shock protein 90 (Hsp90) is a molecular chaperone involved in folding and stabilizing multiple intracellular proteins that have roles in cell activation…”
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Proof-of-Concept Rapid Diagnostic Test for Onchocerciasis: Exploring Peptide Biomarkers and the Use of Gold Nanoshells as Reporter Nanoparticles by Gonzalez-Moa, Maria J., Van Dorst, Bieke, Lagatie, Ole, Verheyen, Ann, Stuyver, Lieven, Biamonte, Marco A.

“…Three O. volvulus immunogenic peptide sequences recently discovered by peptide microarray were adapted to a lateral flow assay (LFA). The LFA employs gold…”
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Rationally Designed High-Affinity 2-Amino-6-halopurine Heat Shock Protein 90 Inhibitors That Exhibit Potent Antitumor Activity by Kasibhatla, Srinivas R, Hong, Kevin, Biamonte, Marco A, Busch, David J, Karjian, Patricia L, Sensintaffar, John L, Kamal, Adeela, Lough, Rachel E, Brekken, John, Lundgren, Karen, Grecko, Roy, Timony, Gregg A, Ran, Yingqing, Mansfield, Robert, Fritz, Lawrence C, Ulm, Edgar, Burrows, Francis J, Boehm, Marcus F

“…Heat shock protein 90 (Hsp90) is a molecular chaperone protein implicated in stabilizing the conformation and maintaining the function of many cell-signaling…”
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Orally Active Purine-Based Inhibitors of the Heat Shock Protein 90 by Biamonte, Marco A, Shi, Jiandong, Hong, Kevin, Hurst, David C, Zhang, Lin, Fan, Junhua, Busch, David J, Karjian, Patricia L, Maldonado, Angelica A, Sensintaffar, John L, Yang, Yong-Ching, Kamal, Adeela, Lough, Rachel E, Lundgren, Karen, Burrows, Francis J, Timony, Gregg A, Boehm, Marcus F, Kasibhatla, Srinivas R

“…Orally active Hsp90 inhibitors are of interest as potential chemotherapeutic agents. Recently, fully synthetic 8-benzyladenines and 8-sulfanyladenines such as…”
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Corrections to Heat Shock Protein 90: Inhibitors in Clinical Trials by Biamonte, Marco A, Van de Water, Ryan, Arndt, Joseph W, Scannevin, Robert H, Perret, Daniel, Lee, Wen-Cherng

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Preparation of 8-(Arylsulfanyl)adenines with Diazonium Salts under Mild, Aerobic Conditions by Biamonte, Marco A, Shi, Jiandong, Hurst, David, Hong, Kevin, Boehm, Marcus F, Kasibhatla, Srinivas R

“…8-(Arylsulfanyl)adenines 11 were prepared in up to 75% yield by reacting the 8-thionoadenine 6 (acetic acid 3-(6-amino-8-thioxo-7,8-dihydropurin-9-yl)propyl…”
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