Search Results - "Biade, S."

Identification of genes associated with platinum drug sensitivity and resistance in human ovarian cancer cells by Roberts, D, Schick, J, Conway, S, Biade, S, Laub, P B, Stevenson, J P, Hamilton, T C, O'Dwyer, P J, Johnson, S W

“…Platinum-based chemotherapeutic regimens are ultimately unsuccessful due to intrinsic or acquired drug resistance. Understanding the molecular basis for…”
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Gene expression profiling of human ovarian tumours by BIADE, S, MARINUCCI, M, SCHICK, J, ROBERTS, D, WORKMAN, G, SAGE, E. H, O'DWYER, P. J, LIVOLSI, V. A, JOHNSON, S. W

“…There is currently a lack of reliable diagnostic and prognostic markers for ovarian cancer. We established gene expression profiles for 120 human ovarian…”
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Chemical agents that promote chromatin compaction radiosensitize tumour cells by Biade, S., Stobbe, C. C., Boyd, J. T., Chapman, J. D.

“…Purpose : Previous studies indicated that cells whose chromatin is naturally compacted at the time of radiation are hypersensitive to radiation-induced…”
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Condensed Chromatin and Cell Inactivation by Single-Hit Kinetics by Chapman, J. D., Stobbe, C. C., Gales, T., Das, I. J., Zellmer, D. L., Biade, S., Matsumoto, Y.

“…Mammalian cells are extremely sensitive to γ rays at mitosis, the time at which their chromatin is maximally condensed. The radiation-induced killing of…”
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The Intrinsic Radiosensitivity of Some Human Tumor Cells Throughout Their Cell Cycles by Biade, S., Stobbe, C. C., Chapman, J. D.

“…The intrinsic radiosensitivity of tumor cells is most frequently reported for asynchronous populations, although cell cycle variation in radiosensitivity is…”
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Transcriptional repression of the anti-apoptotic survivin gene by wild type p53 by Hoffman, William H, Biade, Siham, Zilfou, Jack T, Chen, Jiandong, Murphy, Maureen

“…Survivin is a member of the inhibitor of apoptosis family. This apoptosis inhibitor also has an evolutionarily conserved role as a mitotic spindle checkpoint…”
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Involvement of Flap Endonuclease 1 in Base Excision DNA Repair by Kim, Kyung, Biade, Siham, Matsumoto, Yoshihiro

“…Base excision repair can proceed in either one of two alternative pathways: a DNA polymerase β-dependent pathway and a proliferating cell nuclear antigen…”
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Lovastatin potentiates the photocytotoxic effect of photofrin II delivered to HT29 human colonic adenocarcinoma cells by low density lipoprotein by Biade, S, Mazière, J C, Mora, L, Santus, R, Mazière, C, Auclair, M, Morlière, P, Dubertret, L

“…A 24 h preculture of HT29-18 human colonic adenocarcinoma cells with the sterol synthesis inhibitor lovastatin at concentrations of 0.1-0.5 microM markedly…”
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Photosensitization by Photofrin II delivered to WI26VA4 SV40-transformed human fibroblasts by low density lipoproteins: inhibition of lipid synthesis and fatty acid uptake by Biade, S, Mazière, J C, Mora, L, Santus, R, Morlière, P, Mazière, C, Salmon, S, Gatt, S, Dubertret, L

“…Irradiation with 365 nm light of Wi26VA4 SV40-transformed human fibroblasts cultured for 24 h in the presence of low density lipoproteins loaded with the…”
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Impairment of Proliferating Cell Nuclear Antigen-dependent Apurinic/Apyrimidinic Site Repair on Linear DNA by Biade, Siham, Sobol, Robert W., Wilson, Samuel H., Matsumoto, Yoshihiro

“…Repair of apurinic/apyrimidinic (AP) sites by mammalian cell extracts was compared using circular and linear DNA substrates. Extracts prepared from DNA…”
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Processing and characterization of the low density lipoprotein receptor in the human colonic carcinoma cell subclone HT29-18: a potential pathway for delivering therapeutic drugs and genes by Mazière, J C, Mazière, C, Emami, S, Noel, B, Poumay, Y, Ronveaux, M F, Chastre, E, Porte, H, Barbu, V, Biade, S

“…Low density lipoprotein (LDL) processing has been investigated in the subcloned human colonic carcinoma cell line HT29-18. LDL binding at 4 degrees C was a…”
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Teratogenic effect of the cholesterol synthesis inhibitor AY 9944 on rat embryos in vitro by Repetto, M, Maziere, J C, Citadelle, D, Dupuis, R, Meier, M, Biade, S, Quiec, D, Roux, C

“…AY 9944 [trans-1,4-bis(2-chlorobenzylaminomethyl) cyclohexane dihydrochloride] is an amphiphilic cationic molecule. This chemical is an established inhibitor…”
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Polarographic needle electrode measurements of oxygen in rat prostate carcinomas: accuracy and reproducibility by Yeh, K A, Biade, S, Lanciano, R M, Brown, D Q, Fenning, M C, Babb, J S, Hanks, G E, Chapman, D C

“…The oxygenation status of tumors may be important for predicting tumor response to therapy. Previous studies with the anaplastic (R3327-AT) and…”
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Potentiation of the photocytotoxic effect of photofrin II: synergistic action of verapamil and lovastatin by Mazière, J C, Mora, L, Biade, S, Mazière, C, Santus, R

“…Photofrin II (P2) is at the present time the most used drug in the photochemotherapy of tumors. As previous studies from our group have demonstrated that P2 is…”
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Antitumor photochemotherapy: biochemical bases, therapeutic uses and perspectives by Mazière, J C, Morlière, P, Biade, S, Santus, R

“…The photodynamic therapy of tumors (PDT) is a recent and promising technique for the treatment of tumors which can be reached by the light (directly or by…”
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