Search Results - "Bi, Yuhai"

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation by Miao, Guangyan, Zhao, Hongyu, Li, Yan, Ji, Mingming, Chen, Yong, Shi, Yi, Bi, Yuhai, Wang, Peihui, Zhang, Hong

“…Autophagy acts as a cellular surveillance mechanism to combat invading pathogens. Viruses have evolved various strategies to block autophagy and even subvert…”
Get full text

A Novel Bat Coronavirus Closely Related to SARS-CoV-2 Contains Natural Insertions at the S1/S2 Cleavage Site of the Spike Protein by Zhou, Hong, Chen, Xing, Hu, Tao, Li, Juan, Song, Hao, Liu, Yanran, Wang, Peihan, Liu, Di, Yang, Jing, Holmes, Edward C., Hughes, Alice C., Bi, Yuhai, Shi, Weifeng

“…The unprecedented pandemic of pneumonia caused by a novel coronavirus, SARS-CoV-2, in China and beyond has had major public health impacts on a global scale…”
Get full text

Standardized assays for determining the catalytic activity and kinetics of peroxidase-like nanozymes by Jiang, Bing, Duan, Demin, Gao, Lizeng, Zhou, Mengjie, Fan, Kelong, Tang, Yan, Xi, Juqun, Bi, Yuhai, Tong, Zhou, Gao, George Fu, Xie, Ni, Tang, Aifa, Nie, Guohui, Liang, Minmin, Yan, Xiyun

“…Nanozymes are nanomaterials exhibiting intrinsic enzyme-like characteristics that have increasingly attracted attention, owing to their high catalytic…”
Get full text

Identification of novel bat coronaviruses sheds light on the evolutionary origins of SARS-CoV-2 and related viruses by Zhou, Hong, Ji, Jingkai, Chen, Xing, Bi, Yuhai, Li, Juan, Wang, Qihui, Hu, Tao, Song, Hao, Zhao, Runchu, Chen, Yanhua, Cui, Mingxue, Zhang, Yanyan, Hughes, Alice C., Holmes, Edward C., Shi, Weifeng

“…Despite the discovery of animal coronaviruses related to SARS-CoV-2, the evolutionary origins of this virus are elusive. We describe a meta-transcriptomic…”
Get full text

A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2 by Wu, Yan, Wang, Feiran, Shen, Chenguang, Peng, Weiyu, Li, Delin, Zhao, Cheng, Li, Zhaohui, Li, Shihua, Bi, Yuhai, Yang, Yang, Gong, Yuhuan, Xiao, Haixia, Fan, Zheng, Tan, Shuguang, Wu, Guizhen, Tan, Wenjie, Lu, Xuancheng, Fan, Changfa, Wang, Qihui, Liu, Yingxia, Zhang, Chen, Qi, Jianxun, Gao, George Fu, Gao, Feng, Liu, Lei

“…Neutralizing antibodies could potentially be used as antivirals against the coronavirus disease 2019 (COVID-19) pandemic. Here, we report isolation of four…”
Get full text

Inference of person-to-person transmission of COVID-19 reveals hidden super-spreading events during the early outbreak phase by Wang, Liang, Didelot, Xavier, Yang, Jing, Wong, Gary, Shi, Yi, Liu, Wenjun, Gao, George F., Bi, Yuhai

“…Coronavirus disease 2019 (COVID-19) was first identified in late 2019 in Wuhan, Hubei Province, China and spread globally in months, sparking worldwide…”
Get full text

MERS, SARS, and Ebola: The Role of Super-Spreaders in Infectious Disease by Wong, Gary, Liu, Wenjun, Liu, Yingxia, Zhou, Boping, Bi, Yuhai, Gao, George F.

“…Super-spreading occurs when a single patient infects a disproportionate number of contacts. The 2015 MERS-CoV, 2003 SARS-CoV, and to a lesser extent 2014–15…”
Get full text

Origin and diversity of novel avian influenza A H7N9 viruses causing human infection: phylogenetic, structural, and coalescent analyses by Liu, Di, PhD, Shi, Weifeng, PhD, Shi, Yi, PhD, Wang, Dayan, PhD, Xiao, Haixia, Li, Wei, MSc, Bi, Yuhai, PhD, Wu, Ying, PhD, Li, Xianbin, BSc, Yan, Jinghua, Prof, Liu, Wenjun, Prof, Zhao, Guoping, Prof, Yang, Weizhong, Prof, Wang, Yu, Prof, Ma, Juncai, Prof, Shu, Yuelong, Prof, Lei, Fumin, Prof, Gao, George F, Prof

“…Summary Background On March 30, 2013, a novel avian influenza A H7N9 virus that infects human beings was identified. This virus had been detected in six…”
Get full text

Epidemiology, Evolution, and Recent Outbreaks of Avian Influenza Virus in China by Su, Shuo, Bi, Yuhai, Wong, Gary, Gray, Gregory C, Gao, George F, Li, Shoujun

“…Novel reassortants of H7N9, H10N8, and H5N6 avian influenza viruses (AIVs) are currently circulating in China's poultry flocks, occasionally infecting humans…”
Get full text

The molecular basis for SARS-CoV-2 binding to dog ACE2 by Zhang, Zengyuan, Zhang, Yanfang, Liu, Kefang, Li, Yan, Lu, Qiong, Wang, Qingling, Zhang, Yuqin, Wang, Liang, Liao, Hanyi, Zheng, Anqi, Ma, Sufang, Fan, Zheng, Li, Huifang, Huang, Weijin, Bi, Yuhai, Zhao, Xin, Wang, Qihui, Gao, George F., Xiao, Haixia, Tong, Zhou, Qi, Jianxun, Sun, Yeping

“…SARS-CoV-2 can infect many domestic animals, including dogs. Herein, we show that dog angiotensin-converting enzyme 2 (dACE2) can bind to the SARS-CoV-2 spike…”
Get full text

Single-Cell Sequencing of Peripheral Mononuclear Cells Reveals Distinct Immune Response Landscapes of COVID-19 and Influenza Patients by Zhu, Linnan, Yang, Penghui, Zhao, Yingze, Zhuang, Zhenkun, Wang, Zhifeng, Song, Rui, Zhang, Jie, Liu, Chuanyu, Gao, Qianqian, Xu, Qumiao, Wei, Xiaoyu, Sun, Hai-Xi, Ye, Beiwei, Wu, Yanan, Zhang, Ning, Lei, Guanglin, Yu, Lingxiang, Yan, Jin, Diao, Guanghao, Meng, Fanping, Bai, Changqing, Mao, Panyong, Yu, Yeya, Wang, Mingyue, Yuan, Yue, Deng, Qiuting, Li, Ziyi, Huang, Yunting, Hu, Guohai, Liu, Yang, Wang, Xiaoqian, Xu, Ziqian, Liu, Peipei, Bi, Yuhai, Shi, Yi, Zhang, Shaogeng, Chen, Zhihai, Wang, Jian, Xu, Xun, Wu, Guizhen, Wang, Fu-Sheng, Gao, George F., Liu, Longqi, Liu, William J.

“…The coronavirus disease 2019 (COVID-19) pandemic poses a current world-wide public health threat. However, little is known about its hallmarks compared to…”
Get full text

Dual-Signal Readout Nanospheres for Rapid Point-of-Care Detection of Ebola Virus Glycoprotein by Hu, Jiao, Jiang, Yong-Zhong, Wu, Ling-Ling, Wu, Zhen, Bi, Yuhai, Wong, Gary, Qiu, Xiangguo, Chen, Jianjun, Pang, Dai-Wen, Zhang, Zhi-Ling

“…Rapid detection of highly contagious pathogens is the key to increasing the probability of survival and reducing infection rates. We developed a sensitive and…”
Get full text

Cryo-EM Structure of the African Swine Fever Virus by Liu, Sheng, Luo, Yuzi, Wang, Yajuan, Li, Shihua, Zhao, Zhennan, Bi, Yuhai, Sun, Junqing, Peng, Ruchao, Song, Hao, Zhu, Dongjie, Sun, Yuan, Li, Su, Zhang, Li, Wang, Wei, Sun, Yeping, Qi, Jianxun, Yan, Jinghua, Shi, Yi, Zhang, Xinzheng, Wang, Peiyi, Qiu, Hua-Ji, Gao, George F.

“…African swine fever virus (ASFV) is a large double-stranded DNA virus with an icosahedral multilayered structure. ASFV causes a lethal swine hemorrhagic…”
Get full text

Metagenomic analysis reveals the microbiome and resistome in migratory birds by Cao, Jian, Hu, Yongfei, Liu, Fei, Wang, Yanan, Bi, Yuhai, Lv, Na, Li, Jing, Zhu, Baoli, Gao, George F

“…Antibiotic-resistant pathogens pose high risks to human and animal health worldwide. In recent years, the role of gut microbiota as a reservoir of antibiotic…”
Get full text

More diversified antibiotic resistance genes in chickens and workers of the live poultry markets by Wang, Yanan, Lyu, Na, Liu, Fei, Liu, William J., Bi, Yuhai, Zhang, Zewu, Ma, Sufang, Cao, Jian, Song, Xiaofeng, Wang, Aiping, Zhang, Gaiping, Hu, Yongfei, Zhu, Baoli, Gao, George Fu

“…•More diversified ARGs were identified the LPMs than the farms.•The live poultry trade may speed up the spread of antibiotic resistance.•LPM workers are…”
Get full text

Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses by Liu, Wei, Li, Jing, Zheng, Weinan, Shang, Yingli, Zhao, Zhendong, Wang, Shanshan, Bi, Yuhai, Zhang, Shuang, Xu, Chongfeng, Duan, Ziyuan, Zhang, Lianfeng, Wang, Yue L, Jiang, Zhengfan, Liu, Wenjun, Sun, Lei

“…RIG-I is a key cytosolic pattern recognition receptor that interacts with MAVS to induce type I interferons (IFNs) against RNA virus infection. In this study,…”
Get full text

Comparative study on virus shedding patterns in nasopharyngeal and fecal specimens of COVID-19 patients by Zhang, Ning, Gong, Yuhuan, Meng, Fanping, Shi, Yi, Wang, Jun, Mao, Panyong, Chuai, Xia, Bi, Yuhai, Yang, Penghui, Wang, Fusheng

Get full text

Integrated gut virome and bacteriome dynamics in COVID-19 patients by Cao, Jiabao, Wang, Cheng, Zhang, Yuqing, Lei, Guanglin, Xu, Kun, Zhao, Na, Lu, Jingjing, Meng, Fanping, Yu, Linxiang, Yan, Jin, Bai, Changqing, Zhang, Shaogeng, Zhang, Ning, Gong, Yuhuan, Bi, Yuhai, Shi, Yi, Chen, Zhu, Dai, Lianpan, Wang, Jun, Yang, Penghui

“…SARS-CoV-2 is the cause of the current global pandemic of COVID-19; this virus infects multiple organs, such as the lungs and gastrointestinal tract. The…”
Get full text

Dominant subtype switch in avian influenza viruses during 2016–2019 in China by Bi, Yuhai, Li, Juan, Li, Shanqin, Fu, Guanghua, Jin, Tao, Zhang, Cheng, Yang, Yongchun, Ma, Zhenghai, Tian, Wenxia, Li, Jida, Xiao, Shuqi, Li, Liqiang, Yin, Renfu, Zhang, Yi, Wang, Lixin, Qin, Yantao, Yao, Zhongzi, Meng, Fanyu, Hu, Dongfang, Li, Delong, Wong, Gary, Liu, Fei, Lv, Na, Wang, Liang, Fu, Lifeng, Yang, Yang, Peng, Yun, Ma, Jinmin, Sharshov, Kirill, Shestopalov, Alexander, Gulyaeva, Marina, Gao, George F., Chen, Jianjun, Shi, Yi, Liu, William J., Chu, Dong, Huang, Yu, Liu, Yingxia, Liu, Lei, Liu, Wenjun, Chen, Quanjiao, Shi, Weifeng

“…We have surveyed avian influenza virus (AIV) genomes from live poultry markets within China since 2014. Here we present a total of 16,091 samples that were…”
Get full text

Highly Pathogenic Avian Influenza A(H5N8) Virus in Wild Migratory Birds, Qinghai Lake, China by Li, Mingxin, Liu, Haizhou, Bi, Yuhai, Sun, Jianqing, Wong, Gary, Liu, Di, Li, Laixing, Liu, Juxiang, Chen, Quanjiao, Wang, Hanzhong, He, Yubang, Shi, Weifeng, Gao, George F, Chen, Jianjun

“…In May 2016, a highly pathogenic avian influenza A(H5N8) virus strain caused deaths among 3 species of wild migratory birds in Qinghai Lake, China. Genetic…”
Get full text