Search Results - "Bi, Yiling"

Assessment of adeno-associated virus purity by capillary electrophoresis-based western by Acevedo, Julyana, Bi, Yiling, Gee, Jessica, Khatwani, Santoshkumar L.

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Assessment of adeno-associated virus purity by capillary electrophoresis-based western by Acevedo, Julyana, Bi, Yiling, Gee, Jessica, Khatwani, Santoshkumar L.

“…A rigorous analytical assessment of recombinant adeno-associated virus (rAAV)-based drug products is critical for their successful development as clinical…”
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Combinatorial virtual library screening analysis of antithrombin binding oligosaccharide motif generation by heparan sulfate 3-O-Sulfotransferase 1 by Sankaranarayanan, Nehru Viji, Bi, Yiling, Kuberan, Balagurunathan, Desai, Umesh R.

“…[Display omitted] Pharmaceutical heparin’s activity arises from a key high affinity and high selectivity antithrombin binding motif, which forms the basis for…”
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Induction of DNA damage and ATF3 by retigeric acid B, a novel topoisomerase II inhibitor, promotes apoptosis in prostate cancer cells by Liu, Yongqing, Gao, Fengbin, Jiang, Hanming, Niu, Leilei, Bi, Yiling, Young, Charles Y.F, Yuan, Huiqing, Lou, Hongxiang

“…Highlights • Retigeric acid B inhibits activity of topoisomerase IIα. • Retigeric acid B triggers cell death by inducing DNA damage and locking DNA damage…”
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Alignment-independent QSAR analysis of SecA inhibitors by Xu, Min, Bi, Yiling, Zhu, Mengyuan, Li, Minyong

“…SecA ATPase plays a crucial role in translocation of membrane and secreted polypeptides and proteins in bacteria and therefore a perfect target for novel…”
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Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease by Bi, Yiling, Might, Matthew, Vankayalapati, Hariprasad, Kuberan, Balagurunathan

“…[Display omitted] N-Glycanase deficiency, or NGLY1 deficiency, is an extremely rare human genetic disease. N-Glycanase, encoded by the gene NGLY1, is an…”
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Erratum: Assessment of adeno-associated virus purity by capillary electrophoresis-based western by Acevedo, Julyana, Bi, Yiling, Gee, Jessica, Khatwani, Santoshkumar L

“…[This corrects the article DOI: 10.1016/j.omtm.2024.101321.]…”
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Transcriptome and functional analysis in a Drosophila model of NGLY1 deficiency provides insight into therapeutic approaches by Owings, Katie G, Lowry, Joshua B, Bi, Yiling, Might, Matthew, Chow, Clement Y

“…Abstract Autosomal recessive loss-of-function mutations in N-glycanase 1 (NGLY1) cause NGLY1 deficiency, the only known human disease of deglycosylation…”
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Understanding Heparin/Hparan Sulfate Biosynthetic Pathway in the Generation of Antithrombin Binding Motif using Combinatorial Virtual Library Screening (CVLS) by Bi, Yiling, Sankaranarayanan, Nehru Viji, Kuberan, Balagurunathan, Desai, Umesh R.

“…Heparin/Heparan sulfate glycosaminoglycans (HS‐GAG), is an essential sulfated polysaccharide that regulates multiple biological and pathological processes…”
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Preparation of Nanosensors for Detecting the Activity of Glycosaminoglycan Cleaving Enzymes by Kalita, Mausam, Joice, April, Le, Khoi Dang, Bi, Yiling, Ramamoorthy, Gurusankar, Antelope, Orlando, Roy, Anindita, Balagurunathan, Kuberan

“…Glycosaminoglycans (GAGs) play crucial roles in several biological processes including cell division, angiogenesis, anticoagulation, neurogenesis, axon…”
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Repurposing of Proton Pump Inhibitors as First Identified Small Molecule Inhibitors of Endo-β-N-acetylglucosaminidase (ENGase) for the Treatment of Rare NGLY1 Genetic Disease by Bi, Yiling, Might, Matthew, Vankayalapati, Hariprasad, Kuberan, Balagurunathan

“…N -glycanase deficiency, or NGLY1 deficiency, is an extremely rare human genetic disease. N -glycanase, encoded by the gene NGLY1 , is an important enzyme…”
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Enhancement on oral absorption of paclitaxel by multifunctional pluronic micelles by Li, Yimu, Bi, Yiling, Xi, Yanwei, Li, Lingbing

“…The aim of the present study is to synthesize Pluronic F127-polyethylenimine-folate (PF127-PEI-FA) copolymer, construct a mixed micelle system with…”
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Applications of Computational Tools and Biochemical Approaches in Elucidating Biogenesis of Antithrombin III Binding Heparan Sulfate Structures, Defining Xyloside-Mediated Glycosaminoglycan Priming Activity, and Discovering Drugs to Treat Human N-Glycanase 1 (NGLY1) Deficiency by Bi, Yiling

“…This dissertation research focuses on exploiting computational modeling and biochemical experiments to understand glycosaminoglycan (GAG) biosynthesis,…”
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Ruthenium(II)- and copper(I)-catalyzed synthesis of click-xylosides and assessment of their glycosaminoglycan priming activity by Mencio, Caitlin P., Garud, Dinesh R., Doi, Yosuke, Bi, Yiling, Vankayalapati, Hariprasad, Koketsu, Mamoru, Kuberan, Balagurunathan

“…[Display omitted] Xylosides are small molecules that serve as primers of glycosaminoglycan biosynthesis. Xyloside mediated modulation of biological functions…”
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